Eyster KM (2016) The estrogen receptors: an overview from different perspectives. Methods Mol Biol 1366:1–10

CAS  PubMed  Google Scholar 

Hamilton KJ, Hewitt SC, Arao Y, Korach KS (2017) Estrogen hormone biology. Curr Top Dev Biol 125:109–146

CAS  PubMed  PubMed Central  Google Scholar 

Lizcano F (2022) Roles of estrogens, estrogen-like compounds, and endocrine disruptors in adipocytes. Front Endocrinol (Lausanne) 13:921504

PubMed  Google Scholar 

Bracht JR, Vieira-Potter VJ, De Souza SR, Öz OK, Palmer BF, Clegg DJ (2020) The role of estrogens in the adipose tissue milieu. Ann N Y Acad Sci 1461:127–143

CAS  PubMed  Google Scholar 

Patel S, Homaei A, Raju AB, Meher BR (2018) Estrogen: the necessary evil for human health, and ways to tame it. Biomed Pharmacother 102:403–411

CAS  PubMed  Google Scholar 

Nelson HD (2008) Menopause. Lancet 371:760–770

PubMed  Google Scholar 

Santoro N, Roeca C, Peters BA, Neal-Perry G (2021) The menopause transition: signs, symptoms, and management options. J Clin Endocrinol Metab 106:1–15

PubMed  Google Scholar 

Geraci A, Calvani R, Ferri E, Marzetti E, Arosio B, Cesari M (2021) Sarcopenia and menopause: the role of estradiol. Front Endocrinol (Lausanne) 12:682012

PubMed  Google Scholar 

Ruan H, Hu J, Zhao J, Tao H, Chi J, Niu X et al (2020) Menopause and frailty: a scoping review. Menopause 27:1185–1195

PubMed  Google Scholar 

Sophocleous A, Idris AI (2014) Rodent models of osteoporosis. BoneKEy Rep 3:614–614

PubMed  PubMed Central  Google Scholar 

Sun B, Yin YZ, Xiao J (2019) An in vivo estrogen deficiency mouse model for screening exogenous estrogen treatments of cardiovascular dysfunction after menopause. J Vis Exp. https://doi.org/10.3791/59536-v

Article  PubMed  Google Scholar 

Tao X, Yan M, Wang L, Zhou Y, Wang Z, Xia T et al (2020) Effects of estrogen deprivation on memory and expression of related proteins in ovariectomized mice. Ann Transl Med 8:356

CAS  PubMed  PubMed Central  Google Scholar 

Zhao H, Li X, Zhang D, Chen H, Chao Y, Wu K et al (2018) Integrative bone metabolomics-lipidomics strategy for pathological mechanism of postmenopausal osteoporosis mouse model. Sci Rep 8:16456

PubMed  PubMed Central  Google Scholar 

Souza VR, Mendes E, Casaro M, Antiorio A, Oliveira FA, Ferreira CM (2019) Description of ovariectomy protocol in mice. Methods Mol Biol 1916:303–309

CAS  PubMed  Google Scholar 

Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradère JP, Le Gonidec S et al (2018) The exerkine apelin reverses age-associated sarcopenia. Nat Med 24:1360–1371

CAS  PubMed  Google Scholar 

Lee SW, Yang J, Kim SY, Jeong HK, Lee J, Kim WJ et al (2015) MicroRNA-26a induced by hypoxia targets HDAC6 in myogenic differentiation of embryonic stem cells. Nucleic Acids Res 43:2057–2073

CAS  PubMed  PubMed Central  Google Scholar 

Folch J, Lees M, Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226:497–509

CAS  PubMed  Google Scholar 

Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911–917

CAS  PubMed  Google Scholar 

Kim HS, Yoo HJ, Lee KM, Song HE, Kim SJ, Lee JO et al (2021) Stearic acid attenuates profibrotic signalling in idiopathic pulmonary fibrosis. Respirology 26:255–263

PubMed  Google Scholar 

Kim HK, Shin MS, Youn BS, Kang GM, Gil SY, Lee CH et al (2015) Regulation of energy balance by the hypothalamic lipoprotein lipase regulator Angptl3. Diabetes 64:1142–1153

CAS  PubMed  Google Scholar 

Koh EH, Yoon JE, Ko MS, Leem J, Yun JY, Hong CH et al (2021) Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis. Gut 70:1954–1964

CAS  PubMed  Google Scholar 

Lee SR, Heo JH, Jo SL, Kim G, Kim SJ, Yoo HJ et al (2021) Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration. Sci Rep 11:8781

CAS  PubMed  PubMed Central  Google Scholar 

Lee HY, Nam S, Kim MJ, Kim SJ, Back SH, Yoo HJ (2021) Butyrate prevents TGF-β1-induced alveolar myofibroblast differentiation and modulates energy metabolism. Metabolites 11:258

CAS  PubMed  PubMed Central  Google Scholar 

Ji M, Jo Y, Choi SJ, Kim SM, Kim KK, Oh B-C et al (2022) Plasma metabolomics and machine learning-driven novel diagnostic signature for non-alcoholic steatohepatitis. Biomedicines 10:1669

CAS  PubMed  PubMed Central  Google Scholar 

Oh J-H, Song S, Rhee H, Lee SH, Kim DY, Choe JC et al (2019) Normal reference plots for the bioelectrical impedance vector in healthy Korean adults. J Korean Med Sci 34:e198

PubMed  PubMed Central  Google Scholar 

Nga HT, Jang IY, Kim DA, Park SJ, Lee JY, Lee S et al (2021) Serum GDF15 level is independent of sarcopenia in older Asian adults. Gerontology 67:525–531

CAS  PubMed  Google Scholar 

Roberts HC, Denison HJ, Martin HJ, Patel HP, Syddall H, Cooper C et al (2011) A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age Ageing 40:423–429

PubMed  Google Scholar 

Jung HW, Park JH, Kim DA, Jang IY, Park SJ, Lee JY et al (2021) Association between serum FGF21 level and sarcopenia in older adults. Bone 145:115877

CAS  PubMed  Google Scholar 

Kim DH, Afilalo J, Shi SM, Popma JJ, Khabbaz KR, Laham RJ et al (2019) Evaluation of changes in functional status in the year after aortic valve replacement. JAMA Intern Med 179:383–391

PubMed  PubMed Central  Google Scholar 

Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J et al (2001) Frailty in older adults: evidence for a phenotype. J Gerontol Series A 56:M146–M157

CAS  Google Scholar 

Jang IY, Lee S, Kim JH, Lee E, Lee JY, Park SJ et al (2020) Lack of association between circulating apelin level and frailty-related functional parameters in older adults: a cross-sectional study. BMC Geriatr 20:420

CAS  PubMed  PubMed Central  Google Scholar 

Rockwood K, Mitnitski A (2007) Frailty in relation to the accumulation of deficits. J Gerontol Series A 62:722–727

Google Scholar 

Lee H, Lee E, Jang I-Y (2020) Frailty and comprehensive geriatric assessment. J Korean Med Sci. https://doi.org/10.3346/jkms.2020.35.e16

Article  PubMed  PubMed Central  Google Scholar 

Kim SJ, Song HE, Lee HY, Yoo HJ (2021) Mass spectrometry-based metabolomics in translational research. Adv Exp Med Biol 1310:509–531

CAS  PubMed  Google Scholar 

Schooneman MG, Vaz FM, Houten SM, Soeters MR (2013) Acylcarnitines: reflecting or inflicting insulin resistance? Diabetes 62:1–8

CAS  PubMed  Google Scholar 

Biolo G, Cederholm T, Muscaritoli M (2014) Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia. Clin Nutr 33:737–748

PubMed  Google Scholar 

Karakelides H, Nair KS (2005) Sarcopenia of aging and its metabolic impact. Curr Top Dev Biol 68:123–148

CAS  PubMed  Google Scholar 

Wilkinson DJ, Rodriguez-Blanco G, Dunn WB, Phillips BE, Williams JP, Greenhaff PL et al (2020) Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing. Aging (Albany NY) 12:12517–12533

CAS  PubMed  Google Scholar 

Uchitomi R, Hatazawa Y, Senoo N, Yoshioka K, Fujita M, Shimizu T et al (2019) Metabolomic analysis of skeletal muscle in aged mice. Sci Rep 9:10425

PubMed