Questionnaire survey on severe hypoglycemia in pediatric patients with diabetes-English version

Urakami T, Hotsubo T, Ogawa Y, Kikuchi T, Usuda R, Matsui K, Hirose M, Hirai Y, Abiru N, Fujiwara I, Mizuno H, Miyako K, Takahashi K, Shimada A. Report from the Committee of Pediatric Diabetes in the Japanese Diabetes Society: a questionnaire survey on severe hypoglycemia in pediatric patients with diabetes. J Japan Diab Soc. 2024;67:202–8.

Google Scholar 

Mochizuki M, Kikuchi T, Urakami T, Kikuchi N, Kawamura T, Yokomichi H, Hoshino T, Matsuura N, Sasaki N, Sugihara S, Amemiya S, on behalf of The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT). Improvement in glycemic control through changes in insulin regimens: findings from a Japanese cohort of children and adolescents with type 1 diabetes. Pediatr Diabetes. 2017;18:435–42.

Article  CAS  PubMed  Google Scholar 

Kikuchi T. Latest knowledge on childhood diabetes: current status of treatment of childhood and adolescent type 1 diabetes in Japan. Japan J Child Nurs Monthly. 2021;244:1234–9.

Google Scholar 

Cengiz E, Danne T, Ahmad T, Ayyavoo A, Beran D, Ehtisham S, Fairchild J, Jarosz-Chobot P, Ng SM, Paterson M, Codner E. ISPAD Clinical Practice Consensus Guidelines 2022: insulin treatment in children and adolescents with diabetes. Pediatr Diabetes. 2022;23:1277–96.

Article  PubMed  Google Scholar 

Tauschmann M, Forlenza G, Hood K, Cardona-Hernandez R, Giani E, Hendrieckx C, DeSalvo DJ, Laffel LM, Saboo B, Wheeler BJ, Latpev DN, Yarhere I, DiMeglio LA, ISPAD Clinical Practice Consensus Guidelines. Diabetes technologies: glucose monitoring. Pediatr Diabetes. 2022;2022(23):1390–405.

Article  Google Scholar 

Abraham MB, Karges B, Dovc K, Naranjo D, Arbelaez AM, Mbogo J, Javelikar G, Jones TW, Mahmud FH. ISPAD Clinical Practice Consensus Guidelines 2022: assessment and management of hypoglycemia in children and adolescents with diabetes. Pediatr Diabetes. 2022;23:1322–40.

Article  PubMed  PubMed Central  Google Scholar 

Urakami T. Severe hypoglycemia: is it still a threat for children and adolescents with type 1 diabetes? Front Endocrinol. 2020;11:609.

Article  Google Scholar 

Urakami T. The advanced diabetes technologies for reduction of the frequency of hypoglycemia and minimizing the occurrence of severe hypoglycemia in children and adolescents with type 1 diabetes. J Clin Med. 2023;12:781.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matyka KA, Crowne EC, Havel PJ, Macdonald IA, Matthews D, Dunger DB. Counterregulation during spontaneous nocturnal hypoglycemia in prepubertal children with type 1 diabetes. Diabetes Care. 1999;22:1144–50.

Article  CAS  PubMed  Google Scholar 

Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group. Prolonged nocturnal hypoglycemia is common during 12 months of continuous glucose monitoring in children and adults with type 1 diabetes. Diabetes Care. 2010;33:1004–8.

Article  PubMed Central  Google Scholar 

Urakami T, Yoshida K, Kuwabara R, Mine Y, Aoki M, Suzuki J, Morioka I. Significance of “time below range” as a glycemic marker derived from continuous glucose monitoring in Japanese children and adolescents with type 1 diabetes. Horm Res in Paediatr. 2020;93:251–7.

Article  CAS  Google Scholar 

Abe Y, Urakami T, Suzuki J, Morita S, Araki M, Mizota M, Sasaki G, Mori J, Tatematsu T, Mine Y, Yoshida K, Kikuchi T. Nighttime hypoglycemia in Japanese children with type 1 diabetes mellitus treated with multiple daily injection insulin therapy. Endocr J. 2023;70:677. https://doi.org/10.1507/endocrj.EJ22-0379.

Article  CAS  PubMed  Google Scholar 

Jones TW, Porter P, Sherwin RS, Davis EA, O’Leary P, Frazer F, Byrne G, Stick S, Tamborlane WV. Decreased epinephrine responses to hypoglycemia during sleep. N Engl J Med. 1998;338:1657–62.

Article  CAS  PubMed  Google Scholar 

Beregszaszi M, Tubiana-Rufi N, Benali K, Noel M, Bloch J, Czernichow P. Nocturnal hypoglycemia in children and adolescents with insulin-dependent diabetes mellitus: prevalence and risk factors. J Pediatr. 1997;131:27–33.

Article  CAS  PubMed  Google Scholar 

Porter PA, Keating B, Byrne G, Jones TW. Incidence and predictive criteria of nocturnal hypoglycemia in young children with insulin-dependent diabetes mellitus. J Pediatr. 1997;130:366–72.

Article  CAS  PubMed  Google Scholar 

Urakami T, Habu M, Suzuki J. DKA and severe hypoglycemia in management of type 1 diabetes during 2003–2013. Pediatr Int. 2014;56:940.

Article  PubMed  Google Scholar 

Chung ST, Haymond MW. Minimizing morbidity of hypoglycemia in diabetes: a review of mini-dose glucagon. J Diabetes Sci Technol. 2015;9:44–51.

Article  CAS  PubMed  Google Scholar 

Rickels MR, Ruedy KJ, Foster NC, Piché CA, Dulude H, Sherr JL, Tamborlane WV, Bethin KE, DiMeglio LA, Wadwa RP, Ahmann AJ, Haller MJ, Nathan BM, Marcovina SM, Rampakakis E, Meng L, Beck RW, T1D Exchange Intranasal Glucagon Investigators. Intranasal glucagon for treatment of insulin-induced hypoglycemia in adults with type 1 diabetes: a randomized crossover noninferiority study. Diabetes Care. 2016;39:264–70.

Article  CAS  PubMed  Google Scholar 

Sherr JL, Ruedy KJ, Foster NC, Foster NC, Piché CA, Dulude H, Rickels MR, Tamborlane WV, Bethin KE, DiMeglio LA, Fox LA, Wadwa RP, Schatz DA, Nathan BM, Marcovina SM, Rampakakis E, Meng L, Beck RW, T1D Exchange Intranasal Glucagon Investigators. Glucagon nasal powder: a promising alternative to intramuscular glucagon in youth with type 1 diabetes. Diabetes Care. 2016;39:555–62.

Article  PubMed  PubMed Central  Google Scholar 

Seaquist ER, Dulude H, Zhang XM, Rabasa-Lhoret R, Tsoukas GM, Conway JR, Weisnagel SJ, Gerety G, Woo VC, Zhang S, Carballo D, Pradhan S, Piché CA, Guzman CB. Prospective study evaluating the use of nasal glucagon for the treatment of moderate to severe hypoglycaemia in adults with type 1 diabetes in a real-world setting. Diabetes Obes Metab. 2018;20:1316–20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsuhisa M, Takita Y, Nasu R, Nagai Y, Ohwaki K, Nagashima H. Nasal glucagon as a viable alternative for treating insulin-induced hypoglycaemia in Japanese patients with type 1 or type 2 diabetes: a phase 3 randomized crossover study. Diabetes Obes Metab. 2020;22:1167–75.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Singh-Franco D, Moreau C, Levin AD, De La Rosa D, Johnson M. Efficacy and usability of intranasal glucagon for the management of hypoglycemia in patients with diabetes: a systematic review. Clin Ther. 2020;42:e177–208.

Article  CAS  PubMed  Google Scholar 

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