Aaron D (2023) The fall of FDA review. Yale J Health Policy Law Ethics 95
Bajaj A, Blum K, Bowirrat A, Gupta A, Baron D, Fugel D, Nicholson A, Fitch T, Downs BW, Bagchi D (2022) DNA directed pro-dopamine regulation coupling subluxation repair, H-Wave® and other neurobiologically based modalities to address complexities of chronic pain in a female diagnosed with reward deficiency syndrome (RDS): emergence of Induction of “Dopamine Homeostasis” in the face of the opioid crisis. J Pers Med 12(9):1416. https://doi.org/10.3390/jpm12091416
Article PubMed PubMed Central Google Scholar
Blum K, Lott L, Siwicki D, Fried L, Hauser M, Simpatico T, Baron D, Howeedy A, Badgaiyan RD (2018) Genetic addiction risk score (GARS™) as a predictor of substance use disorder: identifying predisposition not diagnosis. Curr Trends Med Diagn Methods. https://doi.org/10.29011/CTMDM-101.100001
Article PubMed PubMed Central Google Scholar
Blum K, Bowirrat A, Baron D, Lott L, Ponce J, Brewer R, Siwicki D, Boyett B, Gondre-Lewis M, Smith D (2020) Biotechnical development of genetic addiction risk score (GARS) and selective evidence for inclusion of polymorphic allelic risk in substance use disorder (SUD). J Syst Integr Neurosci. https://doi.org/10.15761/JSIN.1000221
Article PubMed PubMed Central Google Scholar
Blum K, Bowirrat A, Lewis MCG, Simpatico TA, Ceccanti M, Steinberg B, Modestino EJ, Thanos PK, Baron D, McLaughlin T (2021) Exploration of epigenetic state hyperdopaminergia (Surfeit) and genetic trait hypodopaminergia (Deficit) during adolescent brain development. Curr Psychopharmacol. https://doi.org/10.2174/2211556010666210215155509
Article PubMed PubMed Central Google Scholar
Blum K, Brodie MS, Pandey SC, Cadet JL, Gupta A, Elman I, Thanos PK, Gondre-Lewis MC, Baron D, Kazmi S (2022a) Researching mitigation of alcohol binge drinking in polydrug abuse: KCNK13 and RASGRF2 gene(s) risk polymorphisms coupled with genetic addiction risk severity (GARS) guiding precision pro-dopamine regulation. J Pers Med 12(6):1009. https://doi.org/10.3390/jpm12061009
Article PubMed PubMed Central Google Scholar
Blum K, Han D, Gupta A, Baron D, Braverman ER, Dennen CA, Kazmi S, Llanos-Gomez L, Badgaiyan RD, Elman I (2022b) Statistical validation of risk alleles in genetic addiction risk severity (GARS) test: early identification of risk for alcohol use disorder (AUD) in 74,566 case–control subjects. J Pers Med 12(9):1385. https://doi.org/10.3390/jpm12091385
Article PubMed PubMed Central Google Scholar
Böttcher L, Chou T, D'Orsogna MR (2023) Forecasting drug overdose mortality by age in the United States at the national and county levels. medRxiv. https://doi.org/10.1101/2023.09.25.23296097
Carr DA, Saigal R, Zhang F, Bransford RJ, Bellabarba C, Dagal A (2019) Enhanced perioperative care and decreased cost and length of stay after elective major spinal surgery. Neurosurg Focus 46(4):E5. https://doi.org/10.3171/2019.1.FOCUS18630
Carrau RL, Prevedello DM, de Lara D, Durmus K, Ozer E (2013) Combined transoral robotic surgery and endoscopic endonasal approach for the resection of extensive malignancies of the skull base. Head Neck 35(11):E351-358. https://doi.org/10.1002/hed.23238
Chen AL-C, Chen TJ, Waite RL, Reinking J, Tung HL, Rhoades P, Downs BW, Braverman E, Braverman D, Kerner M (2009) Hypothesizing that brain reward circuitry genes are genetic antecedents of pain sensitivity and critical diagnostic and pharmacogenomic treatment targets for chronic pain conditions. Med Hypotheses 72(1):14–22. https://doi.org/10.1016/j.mehy.2008.07.059
Chen W, Guo S, Wang S (2016) MicroRNA-16 alleviates inflammatory pain by targeting Ras-related protein 23 (RAB23) and inhibiting p38 MAPK activation. Med Sci Monit Int Med J Exp Clin Res 22:3894. https://doi.org/10.12659/msm.897580
Chidambaran V, Mavi J, Esslinger H, Pilipenko V, Martin L, Zhang K, Sadhasivam S (2015) Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents. Pharmacogenomics J 15(3):255–262. https://doi.org/10.1038/tpj.2014.59
Article CAS PubMed Google Scholar
Chou W-Y, Wang C-H, Liu P-H, Liu C-C, Tseng C-C, Jawan B (2006a) Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy. J Am Soc Anesthesiol 105(2):334–337. https://doi.org/10.1097/00000542-200608000-00016
Chou WY, Yang LC, Lu HF, Ko JY, Wang CH, Lin SH, Lee TH, Concejero A, Hsu CJ (2006b) Association of μ-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty. Acta Anaesthesiol Scand 50(7):787–792. https://doi.org/10.1111/j.1399-6576.2006.01058.x
Article CAS PubMed Google Scholar
Cook-Sather SD, Li J, Goebel TK, Sussman EM, Rehman MA, Hakonarson H (2014) TAOK3, a novel genome-wide association study locus associated with morphine requirement and postoperative pain in a retrospective pediatric day surgery population. PAIN® 155(9):1773–1783. https://doi.org/10.1016/j.pain.2014.05.032
Article CAS PubMed Google Scholar
Cottrill E, Pennington Z, Ahmed AK, Jiang B, Ehresman J, Zhu A, Perdomo-Pantoja A, Lubelski D, Sciubba DM, Witham T (2021) First report of pharmacogenomic profiling in an outpatient spine setting: preliminary results from a pilot study. World Neurosurg 145:e21–e31. https://doi.org/10.1016/j.wneu.2020.09.007
Coulbault L, Beaussier M, Verstuyft C, Weickmans H, Dubert L, Trégouet D, Descot C, Parc Y, Lienhart A, Jaillon P (2006) Environmental and genetic factors associated with morphine response in the postoperative period. Clin Pharmacol Ther 79(4):316–324. https://doi.org/10.1016/j.clpt.2006.01.007
Article CAS PubMed Google Scholar
Cram P, Landon BE, Matelski J, Ling V, Perruccio AV, Paterson JM, Rampersaud YR (2019) Utilization and outcomes for spine surgery in the United States and Canada. Spine (phila Pa 1976) 44(19):1371–1380. https://doi.org/10.1097/BRS.0000000000003083
Dai Z, Chu H, Ma J, Yan Y, Zhang X, Liang Y (2018) The regulatory mechanisms and therapeutic potential of microRNAs: from chronic pain to morphine tolerance. Front Mol Neurosci 11:80. https://doi.org/10.3389/fnmol.2018.00080
Article CAS PubMed PubMed Central Google Scholar
Dasgupta N, Beletsky L, Ciccarone D (2018) Opioid crisis: no easy fix to its social and economic determinants. Am J Public Health 108(2):182–186. https://doi.org/10.2105/AJPH.2017.304187
Article PubMed PubMed Central Google Scholar
Dennen CA, Blum K, Bowirrat A, Thanos PK, Elman I, Ceccanti M, Badgaiyan RD, McLaughlin T, Gupta A, Bajaj A (2022) Genetic addiction risk severity assessment identifies polymorphic reward genes as antecedents to reward deficiency syndrome (RDS) hypodopaminergia’s effect on addictive and non-addictive behaviors in a nuclear family. J Pers Med 12(11):1864. https://doi.org/10.3390/jpm12111864
Article PubMed PubMed Central Google Scholar
Downs BW, Blum K, Baron D, Bowirrat A, Lott L, Brewer R, Boyett B, Siwicki D, Roy AK, Podesta A (2019) Death by opioids: are there non-addictive scientific solutions? J Syst Integr Neurosci. https://doi.org/10.15761/JSIN.1000211
Article PubMed PubMed Central Google Scholar
Dufour R, Mardekian J, Pasquale MK, Schaaf D, Andrews GA, Patel NC (2014) Understanding predictors of opioid abuse: predictive model development and validation. Am J Pharm Benefits 6(5):208–216
El Ibrahimi S, Hendricks MA, Little K, Ritter GA, Flores D, Loy B, Wright D, Weiner SG (2023) The association between community social vulnerability and prescription opioid availability with individual opioid overdose. Drug Alcohol Depend 252:110991. https://doi.org/10.1016/j.drugalcdep.2023.110991
Ettienne EB, Chapman E, Maneno M, Ofoegbu A, Wilson B, Settles-Reaves B, Clarke M, Dunston G, Rosenblatt K (2017) Pharmacogenomics-guided policy in opioid use disorder (OUD) management: an ethnically-diverse case-based approach. Addict Behav Rep 6:8–14. https://doi.org/10.1016/j.abrep.2017.05.001
Article PubMed PubMed Central Google Scholar
Ettienne EB, Ofoegbu A, Maneno MK, Briggs J, Ezeude G, Williams S, Walker C, Chapman E (2019) Pharmacogenomics and opioid use disorder: clinical decision support in an African American cohort. J Natl Med Assoc 111(6):674–681. https://doi.org/10.1016/j.jnma.2019.09.006
Fried L, Modestino EJ, Siwicki D, Lott L, Thanos PK, Baron D, Badgaiyan RD, Ponce JV, Giordano J, Downs WB (2020) Hypodopaminergia and “Precision Behavioral Management” (PBM): it is a generational family affair. Curr Pharm Biotechnol 21(6):528–541. https://doi.org/10.2174/1389201021666191210112108
Article CAS PubMed Google Scholar
Friedman SR, Krawczyk N, Perlman DC, Mateu-Gelabert P, Ompad DC, Hamilton L, Nikolopoulos G, Guarino H, Cerdá M (2020) The opioid/overdose crisis as a dialectics of pain, despair, and one-sided struggle. Front Public Health 8:540423.
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