Louis DN, Perry A, Wesseling P et al (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro-Oncol 23:1231–1251
Article CAS PubMed PubMed Central Google Scholar
Ostrom QT, Cioffi G, Waite K, Kruchko C, Barnholtz-Sloan JS (2021) CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014–2018. Neuro-Oncol 23:iii1-105
Article PubMed PubMed Central Google Scholar
Tan AC, Ashley DM, López GY, Malinzak M, Friedman HS, Khasraw M (2020) Management of glioblastoma: State of the art and future directions. CA Cancer J Clin 70:299–312
Lapointe S, Perry A, Butowski NA (2018) Primary brain tumours in adults. The Lancet 392:432–446
Ansell SM, Lesokhin AM, Borrello I et al (2015) PD-1 blockade with nivolumab in relapsed or refractory Hodgkin’s lymphoma. N Engl J Med 372:311–319
Yi M, Zheng X, Niu M, Zhu S, Ge H, Wu K (2022) Combination strategies with PD-1/PD-L1 blockade: current advances and future directions. Mol Cancer 21:28
Article PubMed PubMed Central Google Scholar
Yang C, Austin F, Richard H et al (2019) Lynch syndrome–associated ultra-hypermutated pediatric glioblastoma mimicking a constitutional mismatch repair deficiency syndrome. Cold Spring Harb Mol Case Stud 5:a003863
Article PubMed PubMed Central Google Scholar
Yin Z, Yu M, Ma T et al (2021) Mechanisms underlying low-clinical responses to PD-1/PD-L1 blocking antibodies in immunotherapy of cancer: a key role of exosomal PD-L1. J Immunother Cancer 9:e001698
Article PubMed PubMed Central Google Scholar
Frederico SC, Hancock JC, Brettschneider EES, Ratnam NM, Gilbert MR, Terabe M (2021) Making a Cold Tumor Hot: The Role of Vaccines in the Treatment of Glioblastoma. Front Oncol [Internet]. [Cited 3 March 2022]; 11. https://www.frontiersin.org/article/10.3389/fonc.2021.672508
Rameshbabu S, Labadie BW, Argulian A, Patnaik A (2021) Targeting innate immunity in cancer therapy. Vaccines 9:138
Article CAS PubMed PubMed Central Google Scholar
Motwani M, Pesiridis S, Fitzgerald KA (2019) DNA sensing by the cGAS–STING pathway in health and disease. Nat Rev Genet 20:657–674
Article CAS PubMed Google Scholar
Li Y, Wilson HL, Kiss-Toth E (2017) Regulating STING in health and disease. J Inflamm Lond Engl [Internet]. [Cited 3 March 2022]; 14. https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5463399/
Sistigu A, Yamazaki T, Vacchelli E et al (2014) Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med 20:1301–1309
Article CAS PubMed Google Scholar
Ito T, Amakawa R, Inaba M, Ikehara S, Inaba K, Fukuhara S (1950) Differential regulation of human blood dendritic cell subsets by IFNs. J Immunol Baltim Md 2001(166):2961–2969
Zitvogel L, Galluzzi L, Kepp O, Smyth MJ, Kroemer G (2015) Type I interferons in anticancer immunity. Nat Rev Immunol 15:405–414
Article CAS PubMed Google Scholar
Huber JP, Farrar JD (2011) Regulation of effector and memory T-cell functions by type I interferon. Immunology 132:466
Article CAS PubMed PubMed Central Google Scholar
Antonelli G, Scagnolari C, Moschella F, Proietti E (2015) Twenty-five years of type I interferon-based treatment: A critical analysis of its therapeutic use. Cytokine Growth Factor Rev 26:121–131
Article CAS PubMed Google Scholar
Agarwala SS, O’Day SJ (2011) Current and future adjuvant immunotherapies for melanoma: blockade of cytotoxic T-lymphocyte antigen-4 as a novel approach. Cancer Treat Rev 37:133–142
Haller O, Kochs G (2011) Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity. J Interferon Cytokine Res Off J Int Soc Interferon Cytokine Res 31:79–87
Woo S-R, Fuertes MB, Corrales L et al (2014) STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. Immunity 41:830–842
Article CAS PubMed PubMed Central Google Scholar
Silginer M, Nagy S, Happold C, Schneider H, Weller M, Roth P (2017) Autocrine activation of the IFN signaling pathway may promote immune escape in glioblastoma. Neuro-Oncol 19:1338–1349
Article CAS PubMed PubMed Central Google Scholar
Ma H, Yang W, Zhang L et al (2019) Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma. Br J Cancer 120:317–330
Article CAS PubMed Google Scholar
Duarte CW, Willey CD, Zhi D et al (2012) Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner. PLoS ONE 7:e29653
Article CAS PubMed PubMed Central Google Scholar
Wang Y, Li C, Chi X et al (2022) Low MxA expression predicts better immunotherapeutic outcomes in glioblastoma patients receiving heat shock protein peptide complex 96 vaccination. Front Oncol 12:865779
Article CAS PubMed PubMed Central Google Scholar
Liberzon A, Birger C, Thorvaldsdóttir H, Ghandi M, Mesirov JP, Tamayo P (2015) The molecular signatures database (MSigDB) hallmark gene set collection. Cell Syst 1:417–425
Article CAS PubMed PubMed Central Google Scholar
Haller O, Stertz S, Kochs G (2007) The Mx GTPase family of interferon-induced antiviral proteins. Microbes Infect 9:1636–1643
Article CAS PubMed Google Scholar
Schneider WM, Chevillotte MD, Rice CM (2014) Interferon-stimulated genes: A complex web of host defenses. Annu Rev Immunol 32:513–545
Article CAS PubMed PubMed Central Google Scholar
Ho SSW, Zhang WYL, Tan NYJ et al (2016) The DNA structure-specific endonuclease MUS81 mediates DNA sensor STING-dependent host rejection of prostate cancer cells. Immunity 44:1177–1189
Article CAS PubMed Google Scholar
Li W, Lu L, Lu J et al (2020) cGAS-STING-mediated DNA sensing maintains CD8+ T cell stemness and promotes antitumor T cell therapy. Sci Transl Med 12:eaay9013
Article CAS PubMed Google Scholar
Turcan S, Rohle D, Goenka A et al (2012) IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483:479–483
Article CAS PubMed PubMed Central Google Scholar
Huang S, Li R, Huang X et al (2019) Association study between methylation in the promoter regions of cGAS, MAVS, and TRAF3 genes and the risk of cervical precancerous lesions and cervical cancer in a southern chinese population. Front Genet 10:1123
Article CAS PubMed PubMed Central Google Scholar
J L, I K, J L et al (2023) Harnessing type I interferon-mediated immunity to target malignant brain tumors. Front Immunol [Internet]. [Cited 31 December 2023]; 14. https://pubmed.ncbi.nlm.nih.gov/37304294/
Bagaev A, Kotlov N, Nomie K et al (2021) Conserved pan-cancer microenvironment subtypes predict response to immunotherapy. Cancer Cell 39:845-865.e7
Comments (0)