Falicov A, Fisher CG, Sparkes J, Boyd MC, Wing PC, Dvorak MF (2006) Impact of surgical intervention on quality of life in patients with spinal metastases. Spine (Phila Pa 1976) 31:2849–2856. https://doi.org/10.1097/01.brs.0000245838.37817.40
Greenlee RT, Murray T, Bolden S, Wingo PA (2000) Cancer statistics, 2000. CA Cancer J Clin 50:7–33. https://doi.org/10.3322/canjclin.50.1.7
Article CAS PubMed Google Scholar
Sutcliffe P, Connock M, Shyangdan D, Court R, Kandala NB, Clarke A (2013) A systematic review of evidence on malignant spinal metastases: natural history and technologies for identifying patients at high risk of vertebral fracture and spinal cord compression. Health Technol Assess 17:1–274. https://doi.org/10.3310/hta17420
Article PubMed PubMed Central Google Scholar
Van den Brande R, Cornips EM, Peeters M, Ost P, Billiet C, Van de Kelft E (2022) Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review. J Bone Oncol 35:100446. https://doi.org/10.1016/j.jbo.2022.100446
Article PubMed PubMed Central Google Scholar
Barzilai O, Laufer I, Yamada Y, Higginson DS, Schmitt AM, Lis E, Bilsky MH (2017) Integrating Evidence-Based Medicine for Treatment of Spinal Metastases Into a Decision Framework: Neurologic, Oncologic, Mechanicals Stability, and Systemic Disease. J Clin Oncol 35:2419–2427. https://doi.org/10.1200/JCO.2017.72.7362
Article CAS PubMed Google Scholar
Di Perna G, Cofano F, Mantovani C, Badellino S, Marengo N, Ajello M, Comite LM, Palmieri G, Tartara F, Zenga F, Ricardi U, Garbossa D (2020) Separation surgery for metastatic epidural spinal cord compression: A qualitative review. J Bone Oncol 25:100320. https://doi.org/10.1016/j.jbo.2020.100320
Article PubMed PubMed Central Google Scholar
Hussain I, Barzilai O, Reiner AS, DiStefano N, McLaughlin L, Ogilvie S, Bilsky M, Laufer I (2018) Patient-reported outcomes after surgical stabilization of spinal tumors: symptom-based validation of the Spinal Instability Neoplastic Score (SINS) and surgery. Spine J 18:261–267. https://doi.org/10.1016/j.spinee.2017.07.008
Colleoni M, Bonetti M, Coates AS, Castiglione-Gertsch M, Gelber RD, Price K, Rudenstam CM, Lindtner J, Collins J, Thurlimann B, Holmberg S, Veronesi A, Marini G, Goldhirsch A (2000) Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group. J Clin Oncol 18:584–590. https://doi.org/10.1200/JCO.2000.18.3.584
Article CAS PubMed Google Scholar
Kumar N, Madhu S, Bohra H, Pandita N, Wang SSY, Lopez KG, Tan JH, Vellayappan BA (2020) Is there an optimal timing between radiotherapy and surgery to reduce wound complications in metastatic spine disease? A systematic review. Eur Spine J 29:3080–3115. https://doi.org/10.1007/s00586-020-06478-5
Zur I, Tzuk-Shina T, Guriel M, Eran A, Kaidar-Person O (2020) Survival impact of the time gap between surgery and chemo-radiotherapy in Glioblastoma patients. Sci Rep 10:9595. https://doi.org/10.1038/s41598-020-66608-3
Article CAS PubMed PubMed Central Google Scholar
Kahl KH, Shiban E, Gutser S, Maurer CJ, Sommer B, Muller H, Konietzko I, Grossert U, Berlis A, Janzen T, Stuben G (2022) Focal cavity radiotherapy after neurosurgical resection of brain metastases: sparing neurotoxicity without compromising locoregional control. Strahlenther Onkol 198:1105–1111. https://doi.org/10.1007/s00066-022-02003-3
Article PubMed PubMed Central Google Scholar
Krauss P, Steininger K, Motov S, Sommer B, Bonk MN, Cortes A, Wolfert C, Stueben G, Shiban E, Kahl KH (2022) Resection of supratentorial brain metastases with intraoperative radiotherapy. Is it safe? Analysis and experiences of a single center cohort. Front Surg 9:1071804. https://doi.org/10.3389/fsurg.2022.1071804
Article PubMed PubMed Central Google Scholar
Mirnezami R, Chang GJ, Das P, Chandrakumaran K, Tekkis P, Darzi A, Mirnezami AH (2013) Intraoperative radiotherapy in colorectal cancer: systematic review and meta-analysis of techniques, long-term outcomes, and complications. Surg Oncol 22:22–35. https://doi.org/10.1016/j.suronc.2012.11.001
Sedlmayer F, Reitsamer R, Wenz F, Sperk E, Fussl C, Kaiser J, Ziegler I, Zehentmayr F, Deutschmann H, Kopp P, Fastner G (2017) Intraoperative radiotherapy (IORT) as boost in breast cancer. Radiat Oncol 12:23. https://doi.org/10.1186/s13014-016-0749-9
Article PubMed PubMed Central Google Scholar
Saito T, Kondo T, Hozumi T, Karasawa K, Seichi A, Nakamura K (2006) Results of posterior surgery with intraoperative radiotherapy for spinal metastases. Eur Spine J 15:216–222. https://doi.org/10.1007/s00586-005-0979-2
Wenz F, Schneider F, Neumaier C, Kraus-Tiefenbacher U, Reis T, Schmidt R, Obertacke U (2010) Kypho-IORT–a novel approach of intraoperative radiotherapy during kyphoplasty for vertebral metastases. Radiat Oncol 5:11. https://doi.org/10.1186/1748-717X-5-11
Article PubMed PubMed Central Google Scholar
Barzilai O, Fisher CG, Bilsky MH (2018) State of the Art Treatment of Spinal Metastatic Disease. Neurosurgery 82:757–769. https://doi.org/10.1093/neuros/nyx567
Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213
Article PubMed PubMed Central Google Scholar
Mak PH, Campbell RC, Irwin MG, American Society of A (2002) The ASA Physical Status Classification: inter-observer consistency. American Society of Anesthesiologists. Anaesth Intensive Care 30:633–640. https://doi.org/10.1177/0310057X0203000516
Schag CC, Heinrich RL, Ganz PA (1984) Karnofsky performance status revisited: reliability, validity, and guidelines. J Clin Oncol 2:187–193. https://doi.org/10.1200/JCO.1984.2.3.187
Article CAS PubMed Google Scholar
Bludau F, Welzel G, Reis T, Schneider F, Sperk E, Neumaier C, Ehmann M, Clausen S, Obertacke U, Wenz F, Giordano FA (2018) Phase I/II trial of combined kyphoplasty and intraoperative radiotherapy in spinal metastases. Spine J 18:776–781. https://doi.org/10.1016/j.spinee.2017.09.011
Wewel JT, O’Toole JE (2020) Epidemiology of spinal cord and column tumors. Neurooncol Pract 7:i5–i9. https://doi.org/10.1093/nop/npaa046
Article PubMed PubMed Central Google Scholar
Bludau F, Welzel G, Reis T, Abo-Madyan Y, Sperk E, Schneider F, Clausen S, Ruder AM, Obertacke U, Ghaly MM, Wenz F, Giordano FA (2019) Combined kyphoplasty and intraoperative radiotherapy (Kypho-IORT) versus external beam radiotherapy (EBRT) for painful vertebral metastases - a randomized phase III study. BMC Cancer 19:430. https://doi.org/10.1186/s12885-019-5666-5
Article PubMed PubMed Central Google Scholar
Huisman M, van der Velden JM, van Vulpen M, van den Bosch MA, Chow E, Oner FC, Yee A, Verkooijen HM, Verlaan JJ (2014) Spinal instability as defined by the spinal instability neoplastic score is associated with radiotherapy failure in metastatic spinal disease. Spine J 14:2835–2840. https://doi.org/10.1016/j.spinee.2014.03.043
van der Velden JM, Versteeg AL, Verkooijen HM, Fisher CG, Chow E, Oner FC, van Vulpen M, Weir L, Verlaan JJ (2017) Prospective Evaluation of the Relationship Between Mechanical Stability and Response to Palliative Radiotherapy for Symptomatic Spinal Metastases. Oncologist 22:972–978. https://doi.org/10.1634/theoncologist.2016-0356
Article PubMed PubMed Central Google Scholar
Shi DD, Hertan LM, Lam TC, Skamene S, Chi JH, Groff M, Cho CH, Ferrone ML, Harris M, Chen YH, Balboni TA (2018) Assessing the utility of the spinal instability neoplastic score (SINS) to predict fracture after conventional radiation therapy (RT) for spinal metastases. Pract Radiat Oncol 8:e285–e294. https://doi.org/10.1016/j.prro.2018.02.001
Versteeg AL, van der Velden JM, Verkooijen HM, van Vulpen M, Oner FC, Fisher CG, Verlaan JJ (2016) The Effect of Introducing the Spinal Instability Neoplastic Score in Routine Clinical Practice for Patients With Spinal Metastases. Oncologist 21:95–101. https://doi.org/10.1634/theoncologist.2015-0266
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