Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72:7–33. https://doi.org/10.3322/caac.21708.
Hassler MR, Bray F, Catto JWF, Grollman AP, Hartmann A, Margulis V, et al. Molecular characterization of upper tract urothelial carcinoma in the era of next-generation sequencing: a systematic review of the current literature. Eur Urol. 2020;78 :209–20. https://doi.org/10.1016/j.eururo.2020.05.039.
Article CAS PubMed Google Scholar
Crivelli JJ, Xylinas E, Kluth LA, Rieken M, Rink M, Shariat SF. Effect of smoking on outcomes of urothelial carcinoma: a systematic review of the literature. Eur Urol. 2014;65:742–54. https://doi.org/10.1016/j.eururo.2013.06.010.
Article CAS PubMed Google Scholar
Van Osch FH, Jochems SH, van Schooten FJ, Bryan RT, Zeegers MP. Significant role of lifetime cigarette smoking in worsening bladder cancer and upper tract urothelial carcinoma prognosis: a meta-analysis. J Urol. 2016;195:872–9. https://doi.org/10.1016/j.juro.2015.10.139.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, et al. European Association of Urology Guidelines on upper urinary tract urothelial carcinoma: 2020 update. Eur Urol. 2021;79:62–79. https://doi.org/10.1016/j.eururo.2020.05.042.
Article CAS PubMed Google Scholar
Laplane L, Duluc D, Bikfalvi A, Larmonier N, Pradeu T. Beyond the tumour microenvironment [published correction appears in Int J Cancer. 2021 Mar 15;148(6):E5]. Int J Cancer. 2019;145:2611–8. https://doi.org/10.1002/ijc.32343.
Article CAS PubMed PubMed Central Google Scholar
Huang C, Bruggeman LA, Hydo LM, Miller RT. Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes. Exp Cell Res. 2012;318:1075–85. https://doi.org/10.1016/j.yexcr.2012.03.011.
Article CAS PubMed PubMed Central Google Scholar
Ahn S, Park H. XIAP is essential for shear stress-enhanced Tyr-576 phosphorylation of FAK. Biochem Biophys Res Commun. 2010;399:256–61. https://doi.org/10.1016/j.bbrc.2010.07.064.
Article CAS PubMed Google Scholar
McGranahan N, Swanton C. Clonal heterogeneity and tumor evolution: past, present, and the future. Cell. 2017;168:613–28. https://doi.org/10.1016/j.cell.2017.01.018.
Article CAS PubMed Google Scholar
McGranahan N, Swanton C. Biological and therapeutic impact of intratumor heterogeneity in cancer evolution. Cancer Cell. 2015;27:15–26. https://doi.org/10.1016/j.ccell.2014.12.001.
Article CAS PubMed Google Scholar
Blanpain C. Tracing the cellular origin of cancer. Nat Cell Biol. 2013;15:126–34. https://doi.org/10.1038/ncb2657.
Article CAS PubMed Google Scholar
Lourenco AR, Ban Y, Crowley MJ, Lee SB, Ramchandani D, Du W, et al. Differential contributions of pre- and post-EMT tumor cells in breast cancer metastasis. Cancer Res. 2020;80:163–9. https://doi.org/10.1158/0008-5472.CAN-19-1427.
Article CAS PubMed Google Scholar
Davis RT, Blake K, Ma D, Gabra MBI, Hernandez GA, Phung AT, et al. Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing. Nat Cell Biol. 2020;22:310–20. https://doi.org/10.1038/s41556-020-0477-0.
Article CAS PubMed Google Scholar
Müller M, Bird TG, Nault JC. The landscape of gene mutations in cirrhosis and hepatocellular carcinoma. J Hepatol. 2020;72:990–1002. https://doi.org/10.1016/j.jhep.2020.01.019.
Article CAS PubMed Google Scholar
Rebouissou S, Nault JC. Advances in molecular classification and precision oncology in hepatocellular carcinoma. J Hepatol. 2020;72:215–29. https://doi.org/10.1016/j.jhep.2019.08.017.
Article CAS PubMed Google Scholar
Baslan T, Hicks J. Unravelling biology and shifting paradigms in cancer with single-cell sequencing. Nat Rev Cancer. 2017;17:557–69. https://doi.org/10.1038/nrc.2017.58.
Article CAS PubMed Google Scholar
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science. 2014;344:1396–401. https://doi.org/10.1126/science.1254257.
Article CAS PubMed PubMed Central Google Scholar
Albini A, Sporn MB. The tumour microenvironment as a target for chemoprevention. Nat Rev Cancer. 2007;7:139–47. https://doi.org/10.1038/nrc2067.
Article CAS PubMed Google Scholar
Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med. 2013;19:1423–37. https://doi.org/10.1038/nm.3394.
Article CAS PubMed PubMed Central Google Scholar
Hosein AN, Huang H, Wang Z, Parmar K, Du W, Huang J, et al. Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution. JCI Insight. 2019;5:e129212. https://doi.org/10.1172/jci.insight.129212.
Wirtz D, Konstantopoulos K, Searson PC. The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat Rev Cancer. 2011;11:512–22. https://doi.org/10.1038/nrc3080.
Article CAS PubMed PubMed Central Google Scholar
Turajlic S, Swanton C. Metastasis as an evolutionary process. Science. 2016;352:169–75. https://doi.org/10.1126/science.aaf2784.
Article CAS PubMed Google Scholar
Ramaswamy S, Ross KN, Lander ES, Golub TR. A molecular signature of metastasis in primary solid tumors. Nat Genet. 2003;33:49–54. https://doi.org/10.1038/ng1060.
Article CAS PubMed Google Scholar
Chen YC, Sahoo S, Brien R, Jung S, Humphries B, Lee W, et al. Single-cell RNA-sequencing of migratory breast cancer cells: discovering genes associated with cancer metastasis. Analyst. 2019;144:7296–309. https://doi.org/10.1039/c9an01358j.
Article CAS PubMed PubMed Central Google Scholar
Kim KT, Lee HW, Lee HO, Song HJ, Jeong da E, Shin S, et al. Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma. Genome Biol. 2016;17:80. https://doi.org/10.1186/s13059-016-0945-9.
Article CAS PubMed PubMed Central Google Scholar
Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, et al. An integrative model of cellular states, plasticity, and genetics for glioblastoma. Cell. 2019;178:835–49.e21. https://doi.org/10.1016/j.cell.2019.06.024.
Article CAS PubMed PubMed Central Google Scholar
Liang Y, Tan Y, Guan B, Guo B, Xia M, Li J, et al. Single-cell atlases link macrophages and CD8+ T-cell subpopulations to disease progression and immunotherapy response in urothelial carcinoma. Theranostics. 2022;12:7745–59. https://doi.org/10.7150/thno.77281.
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