Abrieu A, Kahana JA, Wood KW, Cleveland DW (2000) CENP-E as an essential component of the mitotic checkpoint in vitro. Cell 102(6):817–826. https://doi.org/10.1016/s0092-8674(00)00070-2
Article CAS PubMed Google Scholar
Akera T, Goto Y, Sato M, Yamamoto M, Watanabe Y (2015) Mad1 promotes chromosome congression by anchoring a kinesin motor to the kinetochore. Nat Cell Biol 17(9):1124–1133. https://doi.org/10.1038/ncb3219
Article CAS PubMed Google Scholar
Bancroft J, Auckland P, Samora CP, McAinsh AD (2015) Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways. J Cell Sci 128(1):171–184. https://doi.org/10.1242/jcs.163659
Article CAS PubMed PubMed Central Google Scholar
Barisic M, Aguiar P, Geley S, Maiato H (2014) Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces. Nat Cell Biol 16(12):1249–1256. https://doi.org/10.1038/ncb3060
Article CAS PubMed Google Scholar
Barisic M, Rajendraprasad G, Steblyanko Y (2021) The metaphase spindle at steady state - mechanism and functions of microtubule poleward flux. Semin Cell Dev Biol 117:99–117. https://doi.org/10.1016/j.semcdb.2021.05.016
Article CAS PubMed Google Scholar
Baudat F, Imai Y, de Massy B (2013) Meiotic recombination in mammals: localization and regulation. Nat Rev Genet 14(11):794–806. https://doi.org/10.1038/nrg3573
Article CAS PubMed Google Scholar
Brown KD, Wood KW, Cleveland DW (1996) The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A. J Cell Sci 109(Pt 5):961–969. https://doi.org/10.1242/jcs.109.5.961
Article CAS PubMed Google Scholar
Chakraborty M, Tarasovetc EV, Zaytsev AV, Godzi M, Figueiredo AC, Ataullakhanov FI, Grishchuk EL (2019) Microtubule end conversion mediated by motors and diffusing proteins with no intrinsic microtubule end-binding activity. Nat Commun 10(1):1673. https://doi.org/10.1038/s41467-019-09411-7
Article ADS CAS PubMed PubMed Central Google Scholar
Chan GK, Schaar BT, Yen TJ (1998) Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. J Cell Biol 143(1):49–63. https://doi.org/10.1083/jcb.143.1.49
Article CAS PubMed PubMed Central Google Scholar
Chan GK, Jablonski SA, Sudakin V, Hittle JC, Yen TJ (1999) Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. J Cell Biol 146(5):941–954. https://doi.org/10.1083/jcb.146.5.941
Article CAS PubMed PubMed Central Google Scholar
Cooke CA, Schaar B, Yen TJ, Earnshaw WC (1997) Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase. Chromosoma 106(7):446–455. https://doi.org/10.1007/s004120050266
Article CAS PubMed Google Scholar
Craske B, Welburn JPI (2020) Leaving no-one behind: how CENP-E facilitates chromosome alignment. Essays Biochem 64(2):313–324. https://doi.org/10.1042/EBC20190073
Article CAS PubMed PubMed Central Google Scholar
Cross RA, McAinsh A (2014) Prime movers: the mechanochemistry of mitotic kinesins. Nat Rev Mol Cell Biol 15(4):257–271. https://doi.org/10.1038/nrm3768
Article CAS PubMed Google Scholar
Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS (2003) Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol 161(2):267–280. https://doi.org/10.1083/jcb.200208091
Article CAS PubMed PubMed Central Google Scholar
Duesbery NS, Choi T, Brown KD, Wood KW, Resau J, Fukasawa K, Cleveland DW, Vande Woude GF (1997) CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II. Proc Natl Acad Sci U S A 94(17):9165–9170. https://doi.org/10.1073/pnas.94.17.9165
Article ADS CAS PubMed PubMed Central Google Scholar
Ferlin A, Arredi B, Foresta C (2006) Genetic causes of male infertility. Reprod Toxicol 22(2):133–141. https://doi.org/10.1016/j.reprotox.2006.04.016
Article CAS PubMed Google Scholar
Foley EA, Kapoor TM (2013) Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore. Nat Rev Mol Cell Biol 14(1):25–37. https://doi.org/10.1038/nrm3494
Article CAS PubMed PubMed Central Google Scholar
Garretson A, Dumont BL, Handel MA (2023) Reproductive genomics of the mouse: implications for human fertility and infertility. Development 150(4):dev201313. https://doi.org/10.1242/dev.201313
Article CAS PubMed PubMed Central Google Scholar
Gudimchuk N, Vitre B, Kim Y, Kiyatkin A, Cleveland DW, Ataullakhanov FI, Grishchuk EL (2013) Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips. Nat Cell Biol 15(9):1079–1088. https://doi.org/10.1038/ncb2831
Article CAS PubMed PubMed Central Google Scholar
Gudimchuk N, Tarasovetc EV, Mustyatsa V, Drobyshev AL, Vitre B, Cleveland DW, Ataullakhanov FI, Grishchuk EL (2018) Probing mitotic CENP-E kinesin with the tethered cargo motion assay and laser tweezers. Biophys J 114(11):2640–2652. https://doi.org/10.1016/j.bpj.2018.04.017
Article CAS PubMed PubMed Central Google Scholar
Gui L, Homer H (2012) Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes. Development 139(11):1941–1946. https://doi.org/10.1242/dev.078352
Article CAS PubMed PubMed Central Google Scholar
Guo Y, Kim C, Ahmad S, Zhang J, Mao Y (2012) CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint. J Cell Biol 198(2):205–217. https://doi.org/10.1083/jcb.201202152
Article CAS PubMed PubMed Central Google Scholar
Handel MA, Schimenti JC (2010) Genetics of mammalian meiosis: regulation, dynamics and impact on fertility. Nat Rev Genet 11(2):124–136. https://doi.org/10.1038/nrg2723
Article CAS PubMed Google Scholar
Harton GL, Tempest HG (2012) Chromosomal disorders and male infertility. Asian J Androl 14(1):32–39. https://doi.org/10.1038/aja.2011.66
Huang Y, Lin L, Liu X, Ye S, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang Y et al (2019) BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res 29(7):562–578. https://doi.org/10.1038/s41422-019-0178-z
Article CAS PubMed PubMed Central Google Scholar
Iegiani G, Gai M, Di Cunto F, Pallavicini G (2021) CENPE inhibition leads to mitotic catastrophe and DNA damage in Medulloblastoma cells. Cancers (Basel) 13(5):1028 Published 2021 Mar 1. https://doi.org/10.3390/cancers13051028
Article CAS PubMed Google Scholar
Jiang H, He X, Wang S, Jia J, Wan Y, Wang Y, Zeng R, Yates J 3rd, Zhu X, Zheng Y (2014) A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting. Dev Cell 28(3):268–281. https://doi.org/10.1016/j.devcel.2013.12.013
Article CAS PubMed PubMed Central Google Scholar
Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS (2004) Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression. J Cell Sci 117(Pt 8):1577–1589. https://doi.org/10.1242/jcs.01006
Article CAS PubMed Google Scholar
Kapoor TM, Lampson MA, Hergert P, Cameron L, Cimini D, Salmon ED, McEwen BF, Khodjakov A (2006) Chromosomes can Congress to the metaphase plate before biorientation. Science 311(5759):388–391. https://doi.org/10.1126/science.1122142
Article ADS CAS PubMed PubMed Central Google Scholar
Kim Y, Heuser JE, Waterman CM, Cleveland DW (2008) CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether. J Cell Biol 181(3):411–419. https://doi.org/10.1083/jcb.200802189
Article CAS PubMed PubMed Central Google Scholar
Krausz C (2011) Male infertility: pathogenesis and clinical diagnosis. Best Pract Res Clin Endocrinol Metab 25(2):271–285. https://doi.org/10.1016/j.beem.2010.08.006
Comments (0)