Prognostic role of serum albumin levels in patients with chronic heart failure

McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O et al (2021) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42(36):3599–3726. https://doi.org/10.1093/eurheartj/ehab368

Article  CAS  PubMed  Google Scholar 

Gale SE, Mardis A, Plazak ME, Kukin A, Reed BN (2021) Management of noncardiovascular comorbidities in patients with heart failure with reduced ejection fraction. Pharmacotherapy 41(6):537–545. https://doi.org/10.1002/phar.2528

Article  PubMed  Google Scholar 

Sciacqua A, Succurro E, Armentaro G, Miceli S, Pastori D, Rengo G, Sesti G (2023) Pharmacological treatment of type 2 diabetes in elderly patients with heart failure: randomized trials and beyond. Heart Fail Rev 28(3):667–681. https://doi.org/10.1007/s10741-021-10182-x

Article  CAS  PubMed  Google Scholar 

Liang L, Zhao X, Huang L, Tian P, Huang B, Feng J, Zhou P, Wang J, Zhang J, Zhang Y (2023) Prevalence and prognostic im-portance of malnutrition, as assessed by four different scoring systems, in elder patients with heart failure. Nutr Metab Cardiovasc Dis 33(5):978–986. https://doi.org/10.1016/j.numecd.2023.01.004

Article  CAS  PubMed  Google Scholar 

Pasini E, Aquilani R, Gheorghiade M, Dioguardi FS (2003) Malnutrition, muscle wasting and cachexia in chronic heart failure: the nutritional approach. Ital Heart J 4(4):232–235

PubMed  Google Scholar 

Araújo JP, Lourenço P, Rocha-Gonçalves F, Ferreira A, Bettencourt P (2011) Nutritional markers and prognosis in cardiac ca-chexia. Int J Cardiol 146(3):359–363. https://doi.org/10.1016/j.ijcard.2009.07.042

Article  PubMed  Google Scholar 

Allen LA, Felker GM, Pocock S, McMurray JJ, Pfeffer MA, Swedberg K, Wang D, Yusuf S, Michelson EL, Granger CB, CHARM Investigators (2009) Liver function abnormalities and outcome in patients with chronic heart failure: data from the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program. Eur J Heart Fail 11(2):170–177

Article  PubMed  PubMed Central  Google Scholar 

von Haehling S, Lainscak M, Springer J, Anker SD (2009) Cardiac cachexia: a systematic overview. Pharmacol Ther 121(3):227–252. https://doi.org/10.1016/j.pharmthera.2008.09.009

Article  CAS  Google Scholar 

Chojkier M (2005) Inhibition of albumin synthesis in chronic diseases: molecular mechanisms. J Clin Gastroenterol 39(4 Suppl 2):S143–S146. https://doi.org/10.1097/01.mcg.0000155514.17715.39

Article  CAS  PubMed  Google Scholar 

Adlbrecht C, Kommata S, Hülsmann M, Szekeres T, Bieglmayer C, Strunk G, Karanikas G, Berger R, Mörtl D, Kletter K et al (2008) Chronic heart failure leads to an expanded plasma volume and pseudoanaemia, but does not lead to a reduction in the body’s red cell volume. Eur Heart J 29(19):2343–2350. https://doi.org/10.1093/eurheartj/ehn359

Article  PubMed  Google Scholar 

Arques S, Ambrosi P (2011) Human serum albumin in the clinical syndrome of heart failure. J Card Fail 17(6):451–458. https://doi.org/10.1016/j.cardfail.2011.02.010

Article  CAS  PubMed  Google Scholar 

Roche M, Rondeau P, Singh NR, Tarnus E, Bourdon E (2008) The antioxidant properties of serum albumin. FEBS Lett 582(13):1783–1787. https://doi.org/10.1016/j.febslet.2008.04.057

Article  CAS  PubMed  Google Scholar 

Liu M, Chan CP, Yan BP, Zhang Q, Lam YY, Li RJ, Sanderson JE, Coats AJ, Sun JP, Yip GW et al (2012) Albumin levels predict survival in patients with heart failure and preserved ejection fraction. Eur J Heart Fail 14(1):39–44. https://doi.org/10.1093/eurjhf/hfr154

Article  CAS  PubMed  Google Scholar 

Metra M, Cotter G, El-Khorazaty J, Davison BA, Milo O, Carubelli V, Bourge RC, Cleland JG, Jondeau G, Krum H et al (2015) Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study. J Card Fail 21(3):179–188. https://doi.org/10.1016/j.cardfail.2014.12.012

Article  PubMed  Google Scholar 

Uthamalingam S, Kandala J, Selvaraj V, Martin W, Daley M, Patvardhan E, Capodilupo R, Moore S, Januzzi JL Jr (2015) Out-comes of patients with acute decompensated heart failure managed by cardiologists versus noncardiologists. Am J Cardi-ol 115(4):466–471. https://doi.org/10.1016/j.amjcard.2014.11.034

Article  Google Scholar 

Arques S, Roux E, Stolidi P, Gelisse R, Ambrosi P (2011) Usefulness of serum albumin and serum total cholesterol in the prediction of hospital death in older patients with severe, acute heart failure. Arch Cardiovasc Dis 104(10):502–508. https://doi.org/10.1016/j.acvd.2011.06.003

Article  PubMed  Google Scholar 

Yanagisawa S, Miki K, Yasuda N, Hirai T, Suzuki N, Tanaka T (2010) Clinical outcomes and prognostic factor for acute heart failure in nonagenarians: impact of hypoalbuminemia on mortality. Int J Cardiol 145(3):574–576. https://doi.org/10.1016/j.ijcard.2010.05.061

Article  PubMed  Google Scholar 

Horwich TB, Kalantar-Zadeh K, MacLellan RW, Fonarow GC (2008) Albumin levels predict survival in patients with systolic heart failure. Am Heart J 155(5):883–889. https://doi.org/10.1016/j.ahj.2007.11.043

Article  CAS  PubMed  Google Scholar 

Lau GT, Tan HC, Kritharides L (2002) Type of liver dysfunction in heart failure and its relation to the severity of tricuspid re-gurgitation. Am J Cardiol 90(12):1405–1409. https://doi.org/10.1016/s0002-9149(02)02886-2

Article  PubMed  Google Scholar 

Arques S, Roux E, Sbragia P, Gelisse R, Pieri B, Ambrosi P (2008) Usefulness of serum albumin concentration for in-hospital risk stratification in frail, elderly patients with acute heart failure. Int J Cardiol 125(2):265–267. https://doi.org/10.1016/j.ijcard.2007.07.094

Article  PubMed  Google Scholar 

Uthamalingam S, Kandala J, Daley M, Patvardhan E, Capodilupo R, Moore SA, Januzzi JL Jr (2010) Serum albumin and mortality in acutely decompensated heart failure. Am Heart J 160(6):1149–1155. https://doi.org/10.1016/j.ahj.2010.09.004

Article  CAS  PubMed  Google Scholar 

Kinugasa Y, Kato M, Sugihara S, Hirai M, Kotani K, Ishida K, Yanagihara K, Kato Y, Ogino K, Igawa O et al (2009) A simple risk score to predict in-hospital death of elderly patients with acute decompensated heart failure–hypoalbuminemia as an additional prognostic factor. Circ J 73(12):2276–2281. https://doi.org/10.1253/circj.cj-09-0498

Article  CAS  PubMed  Google Scholar 

Arques S, Pieri B, Biegle G, Roux E, Gelisse R, Jauffret B (2009) Comparative value of B-type natriuretic peptide and serum al-bumin concentration in the prediction of in-hospital mortality in elderly patients admitted for acute severe heart failure. Ann Cardiol Angeiol (Paris) 58(5):279–283. https://doi.org/10.1016/j.ancard.2009.09.003

Article  CAS  PubMed  Google Scholar 

Domínguez JP, Harriague CM, García-Rojas I, González G, Aparicio T, González-Reyes A (2010) Acute heart failure in patients over 70 years of age: Precipitating factors of decompensation. Rev Clin Esp 210(10):497–504. https://doi.org/10.1016/j.rce.2010.04.020

Article  PubMed  Google Scholar 

López Castro J, Almazán Ortega R, De Juan P, Romero M, González Juanatey JR (2010) Mortality prognosis factors in heart failure in a cohort of North-West Spain. EPICOUR study. Rev Clin Esp 210(9):438–447. https://doi.org/10.1016/j.rce.2010.02.009

Article  PubMed  Google Scholar 

Anker SD, Doehner W, Rauchhaus M, Sharma R, Francis D, Knosalla C, Davos CH, Cicoira M, Shamim W, Kemp M et al (2003) Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging. Circulation 107(15):1991–1997. https://doi.org/10.1161/01.CIR.0000065637.10517.A0

Article  PubMed  Google Scholar 

Jackson CE, Bezlyak V, Tsorlalis IK et al (2009) Multimarker laboratory testing in acute decompensated heart failure (ADHF) how much prognostic information do novel biomarkers BNP, troponin and CRP provide in addition to routine laboratory tests? Eur Heart J 30:711

Google Scholar 

Feng KY, Ambrosy AP, Zhou Z, Li D, Kong J, Zaroff JG, Mishell JM, Ku IA, Scotti A, Coisne A, Trial Investigators COAPT et al (2023) Association between serum albumin and outcomes in heart failure and secondary mitral regurgitation: the COAPT trial. Eur J Heart Fail 25(4):553–561. https://doi.org/10.1002/ejhf.2809

Article  CAS  PubMed  Google Scholar 

Gotsman I, Shauer A, Zwas DR, Tahiroglu I, Lotan C, Keren A (2019) Low serum albumin: A significant predictor of reduced survival in patients with chronic heart failure. Clin Cardiol 42(3):365–372. https://doi.org/10.1002/clc.23153

Article  PubMed  PubMed Central  Google Scholar 

El Iskandarani M, El Kurdi B, Murtaza G, Paul TK, Refaat MM (2021) Prognostic role of albumin level in heart failure: A systematic review and meta-analysis. Medicine (Baltimore) 100(10):e24785

Article  PubMed  Google Scholar 

Schupp T, Behnes M, Rusnak J, Ruka M, Dudda J, Forner J, Egner-Walter S, Barre M, Abumayyaleh M, Bertsch T et al (2023) Does albumin predict the risk of mortality in patients with cardiogenic shock? Int J Mol Sci 24(8):7375. https://doi.org/10.3390/ijms24087375

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chao P, Cui X, Wang S, Zhang L, Ma Q, Zhang X (2022) Serum albumin and the short-term mortality in individuals with congestive heart failure in intensive care unit: an analysis of MIMIC. Sci Rep 12(1):16251. https://doi.org/10.1038/s41598-022-20600-1

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vellas B, Villars H, Abellan G, Soto ME, Rolland Y, Guigoz Y, Morley JE, Chumlea W, Salva A, Rubenstein LZ et al (2006) Overview of the MNA - Its history and challenges. J Nutr Health Aging 10(6):456–463

CAS  PubMed  Google Scholar 

Comments (0)

No login
gif