Dynamic intervention strategies await inclusion in clinical evidence synthesis

In the first half of this year, an article about the next generation of evidence-based medicine1 was published in Nature  Medicine, emphasising the growing significance of real-world data in future evidence-based practice and research, providing an opportunity for the evidence accumulation of dynamic intervention (DI) strategies (spanning sequential designs to real-time feedback protocols) in various diseases, as is patient-centric, adaptable and pivotal for modern patient care.

Most intervention meta-analyses address static interventions, diverging from dynamic clinical practices in multistage diseases such as the facial neuritis, primarily comparing positive interventions to controls or other therapies, overlooking real-world adaptive strategies used at different disease stages. For facial neuritis, the early stage may benefit more from gentle acupuncture and …

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