aDepartment of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland

bDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

cDepartment of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman, Jordan

Correspondence to Mohammed H. Abdulla, Department of Physiology, University College Cork, Western Gateway Building, Western Road, T12 XF62, Cork, Ireland. E-mail: [email protected]

Abbreviations: 2K1C, two-kidney one-clip; AUC, area under the curve; DOCA, deoxycorticosterone acetate; DRG, dorsal root ganglion; HR, heart rate; IL-1β, interleukin 1-β; KCl, potassium chloride; MAP, mean arterial pressure; NaCl, sodium chloride; NF-κB, nuclear factor kappa B; nNOS, nitric oxide synthase; NO, nitric oxide; RSNA, renal sympathetic nerve activity; SHR, spontaneously hypertensive rats; SP, substance P; TNF-α, tumour necrosis factor-α

Received 2 October, 2023

Revised 26 January, 2024

Accepted 31 January, 2024

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