aDepartment of Pharmacology, Institute of Biomedical Sciences, University of São Paulo (USP), Brazil

bUniversity of Glasgow, Institute of Cardiovascular & Medical Sciences

cKing's College London British Heart Foundation Centre, School of Cardiovascular Medicine and Sciences, London,

dSchool of Veterinary Medicine, University of Surrey, Guildford, UK

eDepartment of Physiological Sciences, State University of Londrina, Londrina, Brazil

fTranslational Research in Gastrointestinal Disorders, University of Leuven, Belgium

gDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo (USP), Brazil

hDepartment of Medicine, Duke University, Durham, North Carolina, USA

iHeart Institute, Faculty of Medicine, University of São Paulo (USP), Brazil

jResearch Institute of the McGill University Health Centre, McGill University, Montreal, Canada

kVeterans Affairs Medical Center, Nashville, Tennessee, USA

lDepartment of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo (USP), Brazil

Correspondence to Lucia Rossetti Lopes, Institute of Biomedical Sciences, University of São Paulo (USP). Av. Prof. Lineu Prestes, 1524, Butantã, São Paulo 05508-000, Brazil. E-mail: [email protected].

Abbreviations: ANG II, angiotensin II; ATF1, cyclic AMP-dependent transcription factor ATF1; BAC, bacitracin; c-Src, tyrosine-protein kinase Src; Cstf, cleavage stimulation factor; Cys, cysteine; DCP-Bio1, cysteine sulfenic acid probe; DHE, dihydroethidium; DMEM, Dulbecco's Modified Eagle Medium; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; ER, endoplasmic reticulum; ERK, extracellular signal-regulated kinases; FBS, fetal bovine sérum; HB-EGF, heparin-binding EGF-like growth factor; HEK-293T, human embryonic kidney cells; IP3, Inositol trisphosphate; NADPH, reduced nicotinamide adenine dinucleotide phosphate; NOR, norepinephrine; Nox, NADPH oxidase; Nox1-/-, Nox1-deficient mice; Nox1, NADPH oxidase 1; Nox2, NADPH oxidase 2; Nox4, NADPH oxidase 4; PDGF, platelet-derived growth factor; PDI, protein disulfide isomerase A1; ROI, regions of interest; ROS, reactive oxygen species; RyR, ryanodine receptor; SERCA, sarco/endoplasmic reticulum calcium ATPase; SHR, spontaneously hypertensive rats; SOC, store-operated calcium channel; SOH, sulfenic acid; STIM1, stromal interaction molecule; VSMC, vascular smooth muscle cell

Received 10 August, 2022

Revised 4 January, 2024

Accepted 22 January, 2024

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (http://www.jhypertension.com).