Inhibition of xanthine oxidase alleviated pancreatic necrosis via HIF-1α-regulated LDHA and NLRP3 signaling pathway in acute pancreatitis
Xanthine oxidase inhibitor
multi-omics
HIF-1α
necrotizing acute pancreatitis
lactate
therapeutic target
NLRP3
metabolic flux
© 2024 Published by Elsevier B.V. on behalf of Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences.
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