Document Type : Original Article

Authors

1 Department of Applied Mathematics sciences, Yazd University, Yazd, Iran

2 Department of Mathematics, Imam Reza International Uiniversity, Mashhad, Iran

3 Department of Statistics, Faculty of Statistics Mathematics and Computer, Allameh Tabataba’i University, Tehran, Iran

4 Department of Statistics, Faculty of Mathematical Sciences, University of Kashan, Kashan, Iran

5 Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

6 School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

7 Department of biostatistics and epidemiology, Loma Linda University, School of Public Health, USA. (retired)

8 Department of Biostatistics and Epidemiology, Loma Linda University, School of Public Health

10.22074/ijfs.2023.1988282.1428

Abstract

Ovarian reserve is one of the most important factors influencing the success of assisted reproductive technologies (ART). Recently the role of the Anti-Mullerian hormone (AMH) in assisted reproductive technology as a marker for the prediction of ovarian response before ART has been studied widely. We aimed to examine the relationship between a large Iranian population.

In this cross-sectional study, we studied data obtained from 1000 infertile couples referred for in-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) to the Research and Clinical Center of Yazd Infertility Clinic. Serum AMH level, oocyte count, number of fertilized oocytes, endometrial thickness, and percentage of mature oocytes were measured. The relationship between AMH serum levels and quality and the number of oocytes and embryos in ART cycles was analyzed. In each table, the exact number of p-value has been written.

In the linear regression model, the log of the variables (Total dose of gonadotropin), Two Pronucleia, log (Estradiol), Total embryo, duration of stimulation, No. of embryo transferred, protocol, and cause of infertility are significant predictors of log (anti-Mullerian hormone).

There appears to be a relationship between serum AMH levels in the early follicular phase and ovarian reserve. Higher serum AMH levels were also associated with shorter ART cycles.

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