Aqdas M, Sung MH (2023) NF-kappaB dynamics in the language of immune cells. Trends Immunol 44:32–43

Article  CAS  PubMed  Google Scholar 

Artunc F, Schleicher E, Weigert C, Fritsche A, Stefan N, Häring HU (2016) The impact of insulin resistance on the kidney and vasculature. Nat Rev Nephrol 12:721–737

Article  CAS  PubMed  Google Scholar 

Atak BM, Duman TT, Aktas G, Kocak MZ, Savli H (2018) Platelet distribution width is associated with type 2 diabetes mellitus and diabetic nephropathy and neuropathy. Natl J Health Sci 3(3):95–98

Article  Google Scholar 

Binukumar BK, Zheng YL, Shukla V, Amin ND, Grant P, Pant HC (2014) TFP5, a peptide derived from p35, a Cdk5 neuronal activator, rescues cortical neurons from glucose toxicity. J Alzheimers Dis 39:899–909

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 11:183–190

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen K, Yu B, Liao JA-O (2021) LncRNA SOX2OT alleviates mesangial cell proliferation and fibrosis in diabetic nephropathy via Akt/mTOR-mediated autophagy. Mol Med 27:71

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen J, Liu Q, He J, Li Y (2022) Immune responses in diabetic nephropathy: pathogenic mechanisms and therapeutic target. Front Immunol 13:958790

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choi JH, Banks AS, Estall JL, Kajimura S, Bostrom P, Laznik D, Ruas JL, Chalmers MJ, Kamenecka TM, Bluher M et al (2010) Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature 466:451–456

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cruz JC, Tsai LH (2004) A Jekyll and Hyde kinase: roles for Cdk5 in brain development and disease. Curr Opin Neurobiol 14:390–394

Article  CAS  PubMed  Google Scholar 

Dai ZW, Cai KD, Xu LC, Wang LL (2020) Perilipin2 inhibits diabetic nephropathy-induced podocyte apoptosis by activating the PPARγ signaling pathway. Mol Cell Probes 53:101584

Article  CAS  PubMed  Google Scholar 

Drapeau N, Lizotte F, Denhez B, Guay A, Kennedy CR, Geraldes P (2013) Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes. Am J Physiol-Endocrinol Metab 304(11):E1188–E1198

Article  CAS  PubMed  Google Scholar 

Ensergueix G, Pallet N, Joly D, Levi C, Chauvet S, Trivin C, Augusto JF, Boudet R, Aboudagga H, Touchard G et al (2020) Ifosfamide nephrotoxicity in adult patients. Clin Kidney J 13:660–665

Article  CAS  PubMed  Google Scholar 

Fox TE, Han X, Kelly S, Merrill AH 2nd, Martin RE, Anderson RE, Gardner TW, Kester M (2006) Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy. Diabetes 55:3573–3580

Article  PubMed  Google Scholar 

García-Carro C, Draibe J, Soler MJ (2023) Onconephrology: update in anticancer drug-related nephrotoxicity. Nephron 147:65–77

Article  PubMed  Google Scholar 

Guilliams M, Bruhns P, Saeys Y, Hammad H, Lambrecht BN (2014) The function of Fcγ receptors in dendritic cells and macrophages. Nat Rev Immunol 14(2):94–108

Article  CAS  PubMed  Google Scholar 

Hayashi D, Shirai Y (2022) The role of diacylglycerol kinase in the amelioration of diabetic nephropathy. Molecules 27(20):6784

Article  CAS  PubMed  PubMed Central  Google Scholar 

Humbert S, Dhavan R, Tsai L (2000) p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton. J Cell Sci 113(Pt 6):975–983

Article  CAS  PubMed  Google Scholar 

Ji YB, Zhuang PP, Ji Z, Wu YM, Gu Y, Gao XY, Pan SY, Hu YF (2017) TFP5 peptide, derived from CDK5-activating cofactor p35, provides neuroprotection in early-stage of adult ischemic stroke. Sci Rep 7(1):40013

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kelley D, Rinn J (2012) Transposable elements reveal a stem cell-specific class of long noncoding RNAs. Genome Biol 13:R107

Article  PubMed  PubMed Central  Google Scholar 

Kim D, Langmead B, Salzberg SL (2015) HISAT: a fast spliced aligner with low memory requirements. Nat Methods 12:357–360

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kishi S, Abe H, Akiyama H, Tominaga T, Murakami T, Mima A, Nagai K, Kishi F, Matsuura M, Matsubara T et al (2011) SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy. J Biol Chem 286:32162–32169

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kong L, Zhang Y, Ye ZQ, Liu XQ, Zhao SQ, Wei L, Gao G (2007) CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine. Nucleic Acids Res 35:W345-349

Article  PubMed  PubMed Central  Google Scholar 

Kumar S, Sinha K, Sharma R, Purohit R, Padwad Y (2019) Phloretin and phloridzin improve insulin sensitivity and enhance glucose uptake by subverting PPARgamma/Cdk5 interaction in differentiated adipocytes. Exp Cell Res 383:111480

Article  CAS  PubMed  Google Scholar 

Langfelder P, Horvath S (2008) WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics 9:559

Article  PubMed  PubMed Central  Google Scholar 

Lee JY, Yang JW, Han BG, Choi SO, Kim JS (2019) Adiponectin for the treatment of diabetic nephropathy. Korean J Intern Med 34:480–491

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li J, Ma W, Zeng P, Wang J, Geng B, Yang J, Cui Q (2015) LncTar: a tool for predicting the RNA targets of long noncoding RNAs. Brief Bioinform 16:806–812

Article  CAS  PubMed  Google Scholar 

Li X, Bai C, Wang H, Wan T, Li Y (2022) LncRNA MEG3 regulates autophagy and pyroptosis via FOXO1 in pancreatic beta-cells. Cell Signal 92:110247

Article  CAS  PubMed  Google Scholar 

Liu B, Deng C, Tan PA-O (2022) Ombuin ameliorates diabetic nephropathy in rats by anti-inflammation and antifibrosis involving Notch 1 and PPAR γ signaling pathways. Drug Dev Res 83:1270–1280

Article  CAS  PubMed  Google Scholar 

Lu J, Chen PP, Zhang JX, Li XQ, Wang GH, Yuan BY, Huang SJ, Liu XQ, Jiang TT, Wang MY et al (2021) GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKα activity. Theranostics 11:4728–4742

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lv J, Cui W, Liu H, He H, Xiu Y, Guo J, Liu H, Liu Q, Zeng T, Chen Y et al (2013) Identification and characterization of long non-coding RNAs related to mouse embryonic brain development from available transcriptomic data. PLoS ONE 8:e71152

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maric C, Sullivan S (2008) Estrogens and the diabetic kidney. Gend Med 5:S103–S113

Article  PubMed  PubMed Central  Google Scholar 

Morgan DO (1997) Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 13:261–291

Article  CAS  PubMed  Google Scholar 

Nasri M, Adibhesami G, Mahdavifard S, Babaeenezhad E, Ahmadvand H (2023) Exogenous glutamine ameliorates diabetic nephropathy in a rat model of type 2 diabetes mellitus through its antioxidant and anti-inflammatory activities. Arch Physiol Biochem 129:363–372

Article  CAS  PubMed  Google Scholar 

Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH (2000) NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron 28:697–711

Article  CAS  PubMed  Google Scholar 

Park SY, Gautier JF, Chon S (2021) Assessment of insulin secretion and insulin resistance in human. Diabetes Metab J 45:641–654

Article  PubMed  PubMed Central  Google Scholar 

Patel V, Carrion K, Hollands A, Hinton A, Gallegos T, Dyo J, Sasik R, Leire E, Hardiman G, Mohamed SA et al (2015) The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-kappaB signaling, and inflammatory gene expression in human aortic valve cells. FASEB J 29:1859–1868

Article  CAS