K Sunami reports research fundings from Ono, Celgene, AbbVie, Takeda, Sanofi, Bristol Myers Squibb, GSK, Chugai, Otsuka and Janssen, and honoraria from Ono, Bristol Myers Squibb, Takeda and Sanofi. S Ikeda reports lecture fees from Janssen. S Ota reports lecture fees from Novartis, Bristol Myers Squibb, Takeda, AstraZeneca, Janssen and AbbVie. N Iriyama reports speakers fees from Ono. T Jo reports research grants from Bristol Myers Squibb and Handai Biken, consulting fees from Novartis, and lecture fees from Eisai, Sanofi, Bristol Myers Squibb, AbbVie, Nippon Shinyaku and Meiji Seika Pharmacia. T Katayama is an employee of Ono. The medical writing support was provided by K Wakimoto (CMIC Co., Ltd), and was funded by Ono Pharmaceuticals Co. Ltd. This research was funded by Ono Pharmaceutical Co., Ltd. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.