MODIFIED AORTIC VALVE REIMPLANTATION IN PATIENTS WITH ACUTE AORTIC DISSECTION TYPE A

ABSTRACT

Background The question of choosing surgical tactics in patients with acute aortic dissection type A unresolved to now. In patients with massive destruction of the aortic root the «gold standard» is the Bentall procedure. Aortic valve reimplantation is an attractive alternative, especially in patients with preserved aortic valve leaflets anatomy.

Objective To compare the results of the use of valve sparing procedure and composite root replacement in patients with acute aortic dissection type A.

Methods At the end, 62 patients were included in the study. Of those, 27 patients undervent aortic valve reimplantation and 35 had Bentall’s operation in the Kouchoukos modification.

Results Preoperative demographic and clinical characteristics were such between the groups. Similar indicators of preoperative malperfusion were observed in both groups. The time of artificial circulation (p=0.125) and aortic clamping time (p=0.001) were longer in the reimplantation group, while the time of circulatory arrest was longer in the Bentall group (p=0.290). The average aortic clamping time was about 30 minutes longer in the first group. Hospital mortality in the reimplantation group was 8.3% and 22.9% in the Bentall group. Mortality from all causes in the long-term period was 6 people in the reimplantation group 25%, 10 people in the Bentall group 28.6%. The degree of aortic regurgitation did not increase in any case until the moment of extreme contact with the patient.

Conclusions Aortic valve reimplantation can be performed with good immediate and long-term results in patients with preserved aortic valve leaflets with acute aortic dissection type A.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

This study did not receive any funding

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

The Ethics Committee of the State Budgetary Healthcare Institution "Research Institute -Regional Clinical Hospital No. 1 named after Professor S.V.Ochapovsky", Health Care Ministry of the Krasnodar Region, approved this study, and it was done regarding the requirements of medical insurance.

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

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I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

Data Availability

All data produced in the present work are contained in the manuscript

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