Research America. U.S. Investments in medical and health research and development. 2016–2020. https://www.researchamerica.org/wp-content/uploads/2022/09/ResearchAmerica-Investment-Report.Final_.January-2022-1.pdf. Accessed 1 Mar 2023.
Gagnon MA, Lexchin J. The cost of pushing pills: a new estimate of pharmaceutical promotion expenditures in the United States. PLoS Med. 2008;5(1): e1. https://doi.org/10.1371/journal.pmed.0050001.
Article PubMed PubMed Central Google Scholar
Finkel KJ, Takata ET, Maffeo-Mitchell CL, et al. Manufacturer financial conflicts of interest are associated with favourable outcomes in randomised controlled trials of liposomal bupivacaine. Br J Anaesth. 2022;129(4):e90–3. https://doi.org/10.1016/j.bja.2022.06.032.
Article CAS PubMed Google Scholar
Davari M, Khorasani E, Tigabu BM. Factors influencing prescribing decisions of physicians: a review. Ethiop J Health Sci. 2018;28(6):795–804. https://doi.org/10.4314/ejhs.v28i6.15.
Article PubMed PubMed Central Google Scholar
Fickweiler F, Fickweiler W, Urbach E. Interactions between physicians and the pharmaceutical industry generally and sales representatives specifically and their association with physicians’ attitudes and prescribing habits: a systematic review. BMJ Open. 2017;7(9):e016408. Published 2017 Sep 27. https://doi.org/10.1136/bmjopen-2017-016408.
Article PubMed PubMed Central Google Scholar
Katz D, Caplan AL, Merz JF. All gifts large and small: toward an understanding of the ethics of pharmaceutical industry gift-giving. Am J Bioeth. 2010;10(10):11–7. https://doi.org/10.1162/15265160360706552.
Price S, O’Donoghue A, Rizzo L, Sapru S, Aikin K. What influences healthcare providers’ prescribing decisions? Results from a national survey. Res Social Adm Pharm. 2021;17(10):1770–9. https://doi.org/10.1016/j.sapharm.2021.01.012.
Wazana A. Physicians and the pharmaceutical industry: is a gift ever just a gift? JAMA. 2000;283(3):373–80. https://doi.org/10.1001/jama.283.3.373.
Article CAS PubMed Google Scholar
Wood SF, Podrasky J, McMonagle MA, Raveendran J, Bysshe T, Hogenmiller A, et al. Influence of pharmaceutical marketing on Medicare prescriptions in the District of Columbia. PLoS ONE. 2017;12(10): e0186060. https://doi.org/10.1371/journal.pone.0186060.
Article CAS PubMed PubMed Central Google Scholar
Fabbri A, Lai A, Grundy Q, Bero LA. The influence of industry sponsorship on the research agenda: a scoping review. Am J Public Health. 2018;108(11):e9–16. https://doi.org/10.2105/AJPH.2018.304677.
Article PubMed PubMed Central Google Scholar
Institute of Medicine (US) Committee on Conflict of Interest in Medical Research, Education, and Practice; Lo B, Field MJ, editors. Conflict of interest in medical research, education, and practice. Washington (DC): National Academies Press (US); 2009. Available from: https://www.ncbi.nlm.nih.gov/books/NBK22940/. Accessed 23 Jan 2023.
Lee K, Bacchetti P, Sim I. Publication of clinical trials supporting successful new drug applications: a literature analysis. PLoS Med. 2008;5(9): e191. https://doi.org/10.1371/journal.pmed.0050191.
Article PubMed PubMed Central Google Scholar
Lundh A, Lexchin J, Mintzes B, Schroll JB, Bero L. Industry sponsorship and research outcome. Cochrane Database Syst Rev. 2017;2(2):MR000033. https://doi.org/10.1002/14651858.MR000033.pub3.
Baskir E, Athauda G, Zeiarati GN, Kashan SB, Camps-Romero E, Gillis M. Active learning to promote early and effective physician interaction with pharmaceutical industry marketing practices. Med Sci Educ. 2020;30(2):727–35. https://doi.org/10.1007/s40670-020-00943-y.
Article PubMed PubMed Central Google Scholar
Kao AC, Braddock C 3rd, Clay M, et al. Effect of educational interventions and medical school policies on medical students’ attitudes toward pharmaceutical marketing practices: a multi-institutional study. Acad Med. 2011;86(11):1454–62. https://doi.org/10.1097/ACM.0b013e3182303895.
Wilkes MS, Hoffman JR. An innovative approach to educating medical students about pharmaceutical promotion. Acad Med. 2001;76(12):1271–7. https://doi.org/10.1097/00001888-200112000-00026.
Article CAS PubMed Google Scholar
Yeh JS, Austad KE, Franklin JM, et al. Medical schools’ industry interaction policies not associated with trainees’ self-reported behavior as residents: results of a national survey. J Grad Med Educ. 2015;7(4):595–602. https://doi.org/10.4300/JGME-D-15-00029.1.
Article PubMed PubMed Central Google Scholar
Kirschner NM, Sulmasy LS, Kesselheim AS. Health policy basics: the physician payment sunshine act and the open payments program. Ann Intern Med. 2014;161(7):519–21. https://doi.org/10.7326/M14-1303.
Austad KE, Avorn J, Kesselheim AS. Medical students’ exposure to and attitudes about the pharmaceutical industry: a systematic review. PLoS Med. 2011;8(5): e1001037. https://doi.org/10.1371/journal.pmed.1001037.
Article PubMed PubMed Central Google Scholar
Hyman PL, Hochman ME, Shaw JG, Steinman MA. Attitudes of preclinical and clinical medical students toward interactions with the pharmaceutical industry. Acad Med. 2007;82(1):94–9. https://doi.org/10.1097/01.ACM.0000249907.88740.ef.
Sierles FS, Brodkey AC, Cleary LM, et al. Medical students’ exposure to and attitudes about drug company interactions: a national survey. JAMA. 2005;294(9):1034–42. https://doi.org/10.1001/jama.294.9.1034.
Article CAS PubMed Google Scholar
Civaner MM. A follow-up study on the effects of an educational intervention against pharmaceutical promotion. PLoS ONE. 2020;15(10): e0240713. https://doi.org/10.1371/journal.pone.0240713.
Article CAS PubMed PubMed Central Google Scholar
Bellin M, McCarthy S, Drevlow L, Pierach C. Medical students’ exposure to pharmaceutical industry marketing: a survey at one U.S. medical school. Acad Med. 2004;79(11):1041–5. https://doi.org/10.1097/00001888-200411000-00005.
Fein EH, Vermillion ML, Uijtdehaage SH. Pre-clinical medical students’ exposure to and attitudes toward pharmaceutical industry marketing. Med Educ Online. 2007;12(1):4465. https://doi.org/10.3402/meo.v12i.4465.
McDonnell JM, Dalton DM, Ahern DP, Welch-Phillips A, Butler JS. Methods to mitigate industry influence in industry sponsored research. Clin Spine Surg. 2021;34(4):143–5. https://doi.org/10.1097/BSD.0000000000001098.
Mecca JT, Gibson C, Giorgini V, Medeiros KE, Mumford MD, Connelly S. Researcher perspectives on conflicts of interest: a qualitative analysis of views from academia. Sci Eng Ethics. 2015;21(4):843–55. https://doi.org/10.1007/s11948-014-9580-6.
Krimsky S. The funding effect in science and its implications for the judiciary. 13 J. L. & Pol'y. 2005. Available at: https://brooklynworks.brooklaw.edu/jlp/vol13/iss1/4. Accessed 17 Apr 2023.
Sterne JAC, Savović J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366: l4898.
Higgins J, Altman D, Gotzsche P, et al. The Cochrane collaboration’s tool for assessing risk of bias in randomized trials. BMJ. 2011;343:1–9.
Price J, Price D, Williams G, Hoffenberg R. Changes in medical student attitudes as they progress through a medical course. J Med Ethics. 1998;24(2):110–7. https://doi.org/10.1136/jme.24.2.110.
Article CAS PubMed PubMed Central Google Scholar
Farah S, Bilszta JL. Teaching medical students how to interact with the pharmaceutical industry: a scoping review. GMS J Med Educ. 2022;39(5):Doc57. https://doi.org/10.3205/zma00157.
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