Preimplantation genetic testing for aneuploidy: predictive embryonic factors

Handyside AH, Kontogianni EH, Hardy K, Winston RM. Pregnancies from biopsied human preimplantational embryos sexed by Y-specific DNA amplification. Nat. 1990;344:768–70.

Article  ADS  CAS  Google Scholar 

Sermon K. Novel technologies emerging for preimplantation genetic diagnosis and preimplantation genetic testing for aneuploidy. Expert Rev Mol Diagn. 2017;17(1):71–82.

Article  CAS  PubMed  Google Scholar 

Verlinsky Y, Cieslak J, Freidine M, Ivakhenko V, Wolf G, Kovalinskaya L, White M, Lifchez A, Kaplan B, Moise J, Valle J, Ginsberg A, Strom C, Kuliev A. Diagnosing and preventing inherited disease: pregnancies following pre-conception diagnosis of common aneuploidies by fluorescence in-situ hybridization. Hum Reprod. 1995;10:923–7.

Article  Google Scholar 

Munne S, Lee A, Rosenwaks Z, Grifo J, Cohen J. Diagnosis of major chromosome aneuploidies in human preimplantation embryos. Hum Reprod. 1993;8:2185–91.

Article  CAS  PubMed  Google Scholar 

McArthur SJ, Leigh D, Marshall JT, De Boer KA, Jansen RPS. Pregnancies and live births after trophectoderm biopsy and preimplantation genetic testing of human blastocysts. Fertil Steril. 2005;84:1628–36.

Article  PubMed  Google Scholar 

Scott RT, Upham KM, Forman EJ, Zhao T, Treff NR. Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial. Fertil Steril. 2013;100:624–30.

Article  PubMed  Google Scholar 

Minasi MG, Greco E. Current aspects of blastocyst culture, biopsy, and vitrification. CCE Curr Trends Clin Embryol. 2014;I:27–33.

Google Scholar 

Gardner DK, Schoolcraft WB. In vitro culture of human blastocysts. In: Jansen R, Mortimer D, editors. Towards Reproductive Certainty: Infertility and Genetics beyond 1999. Carnforth: Parthenon Press; 1999. p. 378–88.

Google Scholar 

Minasi MG, Colasante A, Riccio T, Ruberti A, Casciani V, Scarcelli F, Spinella F, Fiorentino F, Varrichio MT, Greco E. Correlation between aneuploidy, standard morphology evaluation and morphokinetic development in 1730 biopsied blastocysts: a consecutive case series study. Hum Reprod. 2016;31:2245–54.

Article  PubMed  Google Scholar 

Kaing A, Kroener LL, Tassin R, Li M, Liu L, Buyalos R, et al. Earlier day of blastocyst development is predictive of embryonic euploidy across all ages: essential data for physician decision-making and counselling patients. J Assist Reprod Genet. 2018;35:119–25.

Article  PubMed  Google Scholar 

Taylor TH, Patrick JL, Gitlin SA, Wilson JM, Crain JL, Griffin DK. Comparison of aneuploidy, pregnancy and live birth rates between day 5 and day 6 blastocysts. Reprod Biomed Online. 2014;29:305–10.

Article  PubMed  Google Scholar 

Hammond ER, Cree LM, Morbeck DE. Should extended blastocyst culture include Day 7? Hum Reprod. 2018;33:991–7.

Article  PubMed  Google Scholar 

Rodriguez-Purata J, Gingold J, Lee J, Whitehouse M, Slifkin R, Briton-Jones C, et al. Hatching status before embryo transfer is not correlated with implantation rate in chromosomally screened blastocysts. Hum Reprod. 2016;31:2458–70.

Article  PubMed  PubMed Central  Google Scholar 

Li N, Guan Y, Ren B, Zhang Y, Du Y, Kong H, Zhang Y, Lou H. Effect of blastocyst morphology and developmental rate on euploidy and live birth rates in preimplantation genetic testing for aneuploidy cycles with single-embryo transfer. Front Endocrinol. 2022;858042:13.

Google Scholar 

Tiegs AW, Sun L, Patounakis G, Scott RT Jr. Worth the wait? Day 7 blastocysts have lower euploidy rates but similar sustained implantation rates as day 5 and day 6 blastocysts. Hum Reprod. 2019;34:1632–9.

Article  CAS  PubMed  Google Scholar 

Greco E, Minasi MG, Fiorentino F. Healthy babies after intrauterine transfer of mosaic aneuploid blastocysts. N Engl J Med. 2015;373:2089–90.

Article  PubMed  Google Scholar 

Cram DS, Leigh D, Handyside A, Rechitsky L, Xu K, Harton G, et al. PGDIS Position Statement on the Transfer of Mosaic Embryos. Reprod Biomed Online. 2019;39(Suppl 1):e1–4.

PubMed  Google Scholar 

Grati FR, Gallazzi G, Branca L, Maggi F, Simoni G, Yaron Y. An evidence-based scoring system for prioritizing mosaic aneuploid embryos following preimplantation genetic screening. Reprod Biomed Online. 2018;36:442–9.

Article  PubMed  Google Scholar 

Ruiz-Alonso M, Blesa D, Díaz-Gimeno P, Gómez E, Fernández-Sánchez M, Carranza F, Carrera J, Vilella F, Pellicer A, Simón C. The endometrial receptivity array for diagnosis and personalised embryo transfer as a treatment for patients with repeated implantation failure. Fertil Steril. 2013;100:818–24.

Article  PubMed  Google Scholar 

Giunco H, Connerney M, Boylan C, Koelper N, Mersereau J, Berger DS. Embryo re-expansion does not affect clinical pregnancy rates in frozen embryo transfer cycles: a retrospective study. J Assist Reprod Genet. 2021;38:2933–9.

Article  PubMed  PubMed Central  Google Scholar 

Patrizio P, Shoham G, Shoham Z, Leong M, Barad DH, Gleicher N. Worldwide live births following the transfer of chromosomally “Abnormal” embryos after PGT/A: results of a worldwide web-based survey. J Assist Reprod Genet. 2019;36:1599–607.

Article  PubMed  PubMed Central  Google Scholar 

Cimadomo D, Capalbo A, Dovere L, Tacconi L, Soscia D, Giancani A, et al. Leave the past behind: women’s reproductive history shows no association with blastocysts’ euploidy and limited association with live birth rates after euploid embryo transfers. Hum Reprod. 2021;36:929–40.

Article  CAS  PubMed  Google Scholar 

Sacchi L, Albani E, Cesana A, Smeraldi A, Parini V, Fabiani M, et al. Preimplantation genetic testing for aneuploidy improves clinical, gestational, and neonatal outcomes in advanced maternal age patients without compromising cumulative live-birth rate. J Assist Reprod Genet. 2019;36(12):2493–504.

Article  PubMed  PubMed Central  Google Scholar 

Sanders KD, Silvestri G, Gordon T, Griffin DK. Analysis of IVF live birth outcomes with and without preimplantation genetic testing for aneuploidy (PGT-A): UK Human Fertilisation and Embryology Authority data collection 2016–2018. J Assist Reprod Genet. 2021;38(12):3277–85.

Article  PubMed  PubMed Central  Google Scholar 

La Marca A, Capuzzo M, Imbrogno MG, Donno V, Spedicato GA, Sacchi S, Minasi MG, Spinella F, Greco P, Fiorentino F, Greco E. The complex relationship between female age and embryo euploidy. Minerva Obstet Gynecol. 2020;73:103–10.

PubMed  Google Scholar 

Awadalla MS, Vestal NL, McGinnis LK, Ahmady A, Paulson RJ. Effect of age and morphology on sustained implantation rate after euploid blastocyst transfer. Reprod Biomed Online. 2021;43:395–403.

Article  PubMed  Google Scholar 

Irani M, O’Neill C, Palermo GD, Xu K, Zhang C, Qin X, et al. Blastocyst development rate influences implantation and live birth rates of similarly graded euploid blastocysts. Fertil Steril. 2018;110:95-102.e1.

Article  PubMed  Google Scholar 

Reig A, Franasiak J, Scott RT, Seli E. The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers. J Assist Reprod Genet. 2020;37:595–602.

Article  PubMed  PubMed Central  Google Scholar 

Cimadomo D, Capalbo A, Levi-Setti PE, Soscia D, Orlando G, Albani E, et al. Associations of blastocyst features, trophectoderm biopsy and other laboratory practice with post-warming behavior and implantation. Hum Reprod. 2018;33:1992–2001.

Article  PubMed  Google Scholar 

Alfarawati S, Fragouli E, Colls P, Stevens J, Gutierrez-Mateo C, Schoolcraft WB, Katz-Jaffe MG, Wells D. The relationship between blastocyst morphology, chromosomal abnormality and embryo gender. Fertil Steril. 2011;95:520–4.

Article  PubMed  Google Scholar 

Capalbo A, Rienzi L, Cimadomo D, Maggiulli R, Elliott T, Wright G, et al. Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centers involving 956 screened blastocysts. Hum Reprod. 2014;29:1173–81.

Article  PubMed  Google Scholar 

Cimadomo D, Soscia D, Vaiarelli A, Maggiulli R, Capalbo A, Ubaldi FM, Rienzi L. Looking past the appearance: a comprehensive description of the clinical contribution of poor-quality blastocysts to increase live birth rates during cycles with aneuploidy testing. Hum Reprod. 2019;34:1206–14.

Article  PubMed  Google Scholar 

Lane S, Reed L, Schoolcraft W, Katz-Jaffe M. Euploid day 7 blastocysts of infertility patients with only slow embryo development have reduced implantation potential. Reprod Med Online. 2022;44:858–65.

Article  Google Scholar 

McDaniel K, Awadalla M, McGinnis L, Ahmady A. Transfer the best and biopsy the rest? Blastocyst euploidy rates differ by morphology and day of biopsy. Arc Gyn Obstet. 2021;303:249–58.

Article  Google Scholar 

Vega M, Breborowicz A, Moshier EL, McGovern PG, Keltz MD. Blastulation rates decline in a linear fashion from euploid to aneuploid embryos with single versus multiple chromosomal errors. Fertil Steril. 2014;102:394–8.

Article  PubMed  Google Scholar 

Deng J, Qianying Z, Cinnioglu C, Kayali R, Lathi R, Behr B. The impact of culture conditions on blastocyst formation and aneuploidy rates: a comparison between single-step and sequential media in a large academic practice. J Assist Reprod Genet. 2020;37:161–9.

Article  PubMed  PubMed Central  Google Scholar 

Sfontouris I, Martins W, Nastri C, Viana I, Navarro P, Raine-Fenning N, van der Poel S, Rienzi L, Racowsky C. Blastocyst culture using single versus sequential media in clinical IVF: a systematic review and meta-analysis of randomized controlled tria’ls. J Assist Reprod Genet. 2016;33:1261–72.

Article  PubMed  PubMed Central  Google Scholar 

Maggiulli R, Giancani A, Cimadomo D, Ubaldi F, Rienzi L. Human blastocyst biopsy and vitrification. J Vis Exp. 2019;26(149).

Oliva M, Briton-Jones C, Gounko D, Lee J, Copperman A, Sekhon L. Factors associated with vitrification-warming survival in 6167 euploid blastocysts. J Assist Reprod Gen. 2021;38:2671–8.

Article  Google Scholar 

Shear MA, Vaughan DA, Modest AM, Seidler EA, Leung AQ, Hacker MR, Sakkas D, Penzias AS. Blasts from the past: is morphology useful in PGT-A tested and untested frozen embryo transfers? Reprod Biomed Online. 2020;41:981–9.

Article 

留言 (0)

沒有登入
gif