The study was supported by JSPS KAKENHI (grant no. A19H040480) and University Grants from the Japanese Ministry of Education, Culture, Sports, Science and Technology. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.