Yoshiji H, Nagoshi S, Akahane T, et al. Evidence-based clinical practice guidelines for liver cirrhosis 2020. J Gastroenterol. 2021;56:593–619.

Article  PubMed  PubMed Central  Google Scholar 

Yoshiji H, Nagoshi S, Akahane T, et al. Evidence-based clinical practice guidelines for liver cirrhosis 2020. Hepatol Res. 2021;51:725–49.

Article  PubMed  Google Scholar 

Lai JC, Tandon P, Bernal W, et al. Malnutrition, frailty, and sarcopenia in patients with cirrhosis: 2021 practice guidance by the american association for the study of liver diseases. Hepatology. 2021;74:1611–44.

Article  PubMed  Google Scholar 

European Association for the Study of the Liver, Electronic address eee. EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis. J Hepatol. 2018;69:406–60.

Article  Google Scholar 

Tantai X, Liu Y, Yeo YH, et al. Effect of sarcopenia on survival in patients with cirrhosis: a meta-analysis. J Hepatol. 2022;76:588–99.

Article  PubMed  Google Scholar 

Alameri HF, Sanai FM, Al Dukhayil M, et al. Six minute walk test to assess functional capacity in chronic liver disease patients. World J Gastroenterol. 2007;13:3996–4001.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Carey EJ, Steidley DE, Aqel BA, et al. Six-minute walk distance predicts mortality in liver transplant candidates. Liver Transpl. 2010;16:1373–8.

Article  PubMed  Google Scholar 

Pimentel C, Amaral ACC, Gonzalez AM, et al. Six-minute walking test performance is associated with survival in cirrhotic patients. World J Hepatol. 2021;13:1791–801.

Article  PubMed  PubMed Central  Google Scholar 

Korean Association for the Study of the L. KASL clinical practice guidelines for liver cirrhosis: varices, hepatic encephalopathy, and related complications. Clin Mol Hepatol. 2020;26:83–127.

Article  Google Scholar 

Hanai T, Nishimura K, Miwa T, et al. Usefulness of nutritional therapy recommended in the Japanese Society of Gastroenterology/Japan Society of Hepatology evidence-based clinical practice guidelines for liver cirrhosis 2020. J Gastroenterol. 2021;56:928–37.

Article  PubMed  Google Scholar 

Tandon P, Ismond KP, Riess K, et al. Exercise in cirrhosis: translating evidence and experience to practice. J Hepatol. 2018;69:1164–77.

Article  PubMed  Google Scholar 

Zenith L, Meena N, Ramadi A, et al. Eight weeks of exercise training increases aerobic capacity and muscle mass and reduces fatigue in patients with cirrhosis. Clin Gastroenterol Hepatol. 2014;12(1920–6): e2.

Google Scholar 

Roman E, Garcia-Galceran C, Torrades T, et al. Effects of an exercise programme on functional capacity, body composition and risk of falls in patients with cirrhosis: a randomized clinical trial. PLoS One. 2016;11: e0151652.

Article  PubMed  PubMed Central  Google Scholar 

Aamann L, Dam G, Borre M, et al. Resistance training increases muscle strength and muscle size in patients with liver cirrhosis. Clin Gastroenterol Hepatol. 2020;18(1179–87): e6.

Google Scholar 

Roman E, Torrades MT, Nadal MJ, et al. Randomized pilot study: effects of an exercise programme and leucine supplementation in patients with cirrhosis. Dig Dis Sci. 2014;59:1966–75.

Article  PubMed  CAS  Google Scholar 

Williams FR, Vallance A, Faulkner T, et al. Home-based exercise in patients awaiting liver transplantation: a feasibility study. Liver Transpl. 2019;25:995–1006.

Article  PubMed  Google Scholar 

Chen HW, Ferrando A, White MG, et al. Home-based physical activity and diet intervention to improve physical function in advanced liver disease: a randomized pilot trial. Dig Dis Sci. 2020;65:3350–9.

Article  PubMed  CAS  Google Scholar 

Garcia-Pagan JC, Santos C, Barbera JA, et al. Physical exercise increases portal pressure in patients with cirrhosis and portal hypertension. Gastroenterology. 1996;111:1300–6.

Article  PubMed  CAS  Google Scholar 

Salo J, Guevara M, Fernandez-Esparrach G, et al. Impairment of renal function during moderate physical exercise in cirrhotic patients with ascites: relationship with the activity of neurohormonal systems. Hepatology. 1997;25:1338–42.

Article  PubMed  CAS  Google Scholar 

Lai JC, Dodge JL, Kappus MR, et al. A multicenter pilot randomized clinical trial of a home-based exercise program for patients with cirrhosis: the strength training intervention (STRIVE). Am J Gastroenterol. 2021;116:717–22.

Article  PubMed  PubMed Central  Google Scholar 

Macias-Rodriguez RU, Ilarraza-Lomeli H, Ruiz-Margain A, et al. Changes in hepatic venous pressure gradient induced by physical exercise in cirrhosis: results of a pilot randomized open clinical trial. Clin Transl Gastroenterol. 2016;7: e180.

Article  PubMed  PubMed Central  Google Scholar 

Kaibori M, Ishizaki M, Matsui K, et al. Perioperative exercise for chronic liver injury patients with hepatocellular carcinoma undergoing hepatectomy. Am J Surg. 2013;206:202–9.

Article  PubMed  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372: n71.

Article  PubMed  PubMed Central  Google Scholar 

Saaiq M, Ashraf B. Modifying, “Pico” Question into “Picos” model for more robust and reproducible presentation of the methodology employed in a scientific study. World J Plast Surg. 2017;6:390–2.

PubMed  PubMed Central  Google Scholar 

Effective Practice and Organisation of Care (EPOC). EPOC Resources for review authors. Oslo: Norwegian Knowledge Centre for the Health Services; 2015. http://www.epoccochraneorg/epoc-specific-resources-review-authors.

Wan X, Wang W, Liu J, et al. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 2014;14:135.

Article  PubMed  PubMed Central  Google Scholar 

Kawaguchi T, Charlton M, Kawaguchi A, et al. Effects of Mediterranean diet in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression analysis of randomized controlled trials. Semin Liver Dis. 2021;41:225–34.

Article  PubMed  Google Scholar 

Izuhara K, Nunomura S, Nanri Y, et al. Periostin: an emerging biomarker for allergic diseases. Allergy. 2019;74:2116–28.

Article  PubMed  Google Scholar 

Wallen MP, Keating SE, Hall A, et al. Exercise training is safe and feasible in patients awaiting liver transplantation: a pilot randomized controlled trial. Liver Transpl. 2019;25:1576–80.

Article  PubMed  Google Scholar 

Henrique DMN, Malaguti C, Limonge TM, et al. Six-minute walking test as a predictor of clinical decompensation in patients with cirrhosis. J Gastrointestin Liver Dis. 2021;30:103–9.

PubMed  Google Scholar 

Duarte-Rojo A, Brown RA, Bloomer PM, et al. A telemedicine alternative to the 6-minute walk test using personal activity trackers in liver transplant candidates. Transplant Direct. 2022;8: e1347.

Article  PubMed  PubMed Central  Google Scholar 

Grgic J, McLlvenna LC, Fyfe JJ, et al. Does aerobic training promote the same skeletal muscle hypertrophy as resistance training? A systematic review and meta-analysis. Sports Med. 2019;49:233–54.

Article  PubMed  Google Scholar 

Hurst C, Robinson SM, Witham MD, et al. Resistance exercise as a treatment for sarcopenia: prescription and delivery. Age Ageing. 2022. https://doi.org/10.1093/ageing/afac003.

Article  PubMed  PubMed Central  Google Scholar 

Praktiknjo M, Clees C, Pigliacelli A, et al. Sarcopenia is associated with development of acute-on-chronic liver failure in decompensated liver cirrhosis receiving transjugular intrahepatic portosystemic shunt. Clin Transl Gastroenterol. 2019;10: e00025.

Article  PubMed  PubMed Central  Google Scholar 

Topan MM, Sporea I, Danila M, et al. Impact of sarcopenia on survival and clinical outcomes in patients with liver cirrhosis. Front Nutr. 2021;8: 766451.

Article  PubMed  PubMed Central  Google Scholar 

Tandon P, Dunn MA, Duarte-Rojo A. Resistance training reduces risk of sarcopenia in patients with cirrhosis. Clin Gastroenterol Hepatol. 2020;18:1036–9.

Article  PubMed  Google Scholar 

Miwa T, Hanai T, Nishimura K, et al. Usefulness of the global leadership initiative on malnutrition criteria to predict sarcopenia and mortality in patients with chronic liver disease. Hepatol Res. 2022;52:928–36.

Article  PubMed  Google Scholar 

Sugiyama Y, Ishizu Y, Ando Y, et al. An improved method to assess skeletal muscle mass in patients with liver cirrhosis based on computed tomography images. Hepatol Res. 2022;52:937–46.

Article  PubMed  CAS  Google Scholar 

Mansouri PM, Ghadami MM, Najafi SSM, et al. The effect of self-management training on self-efficacy of cirrhotic patients referring to transplantation center of nemazee hospital: a randomized controlled clinical trial. Int J Community Based Nurs Midwifery. 2017;5:256–63.

PubMed  Google Scholar 

Kruger C, McNeely ML, Bailey RJ, et al. Home exercise training improves exercise capacity in cirrhosis patients: role of exercise adherence. Sci Rep. 2018;8:99.

Article  PubMed  PubMed Central  Google Scholar