Association of serum testosterone with chronic obstructive pulmonary disease (COPD) in a nationally representative sample of White, Black, and Hispanic men

Mannino DM (2022) The changing definition and perception of COPD. Respir Care 67(6):750–755

Article  PubMed  Google Scholar 

Xu J, Murphy SL, Kochanek KD, Arias E (2022) Mortality in the United States. NCHS Data Br 456:1–8

Google Scholar 

Mousavi SA, Kouchari MR, Samdani-Fard SH, Gilvaee ZN, Arabi MJT (2012) Relationship between serum levels of testosterone and the severity of chronic obstructive pulmonary disease. Tanaffos 11(3):32–35

CAS  PubMed  PubMed Central  Google Scholar 

Karakou E, Glynos C, Samara KD, Msaouel P, Koutsilieris M, Vassilakopoulos T (2013) Profile of endocrinological derangements affecting PSA values in patients with COPD. In Vivo 27(5):641–649

CAS  PubMed  Google Scholar 

Scott TW (2023) Chronic obstructive pulmonary disease: risk factors and risk reduction. UpToDate. https://www.uptodate.com/contents/chronic-obstructive-pulmonary-disease-risk-factors-and-risk-reduction

Camiciottoli G, Bigazzi F, Magni C et al (2016) Prevalence of comorbidities according to predominant phenotype and severity of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 11:2229–2236

Article  PubMed  PubMed Central  Google Scholar 

Balasubramanian V, Naing S (2012) Hypogonadism in chronic obstructive pulmonary disease: incidence and effects. Curr Opin Pulm Med 18(2):112–117. https://doi.org/10.1097/MCP.0b013e32834feb37

Article  CAS  PubMed  Google Scholar 

Slim A, Hedhli A, Ouahchi Y et al (2020) Testosterone and chronic obstructive pulmonary disease. Rev Mal Respir 37(10):790–799. Testosteronemie et bronchopneumopathie chronique obstructive. https://doi.org/10.1016/j.rmr.2020.08.013

Article  CAS  PubMed  Google Scholar 

Rubinsztajn R, Przybylowski T, Maskey-Warzechowska M, Karwat K, Chazan R (2019) Serum testosterone depression as a factor influencing the general condition in chronic obstructive pulmonary disease patients. Adv Clin Exp Med 28(6):783–788. https://doi.org/10.17219/acem/94153

Article  PubMed  Google Scholar 

Khera M, Adaikan G, Buvat J et al (2016) Diagnosis and treatment of testosterone deficiency: recommendations from the Fourth International Consultation for Sexual Medicine (ICSM 2015). J Sex Med 13(12):1787–1804

Article  PubMed  Google Scholar 

Buvat J, Maggi M, Guay A, Torres LO (2013) Testosterone deficiency in men: systematic review and standard operating procedures for diagnosis and treatment. J Sex Med 10(1):245–284

Article  CAS  PubMed  Google Scholar 

Mulhall JP, Trost LW, Brannigan RE et al (2018) Evaluation and management of testosterone deficiency: AUA guideline 200(2):423–432. https://doi.org/10.1016/j.juro.2018.03.115

Article  Google Scholar 

Lopez DS, Canfield S, Wang R (2016) Testosterone replacement therapy and the heart: friend, foe or bystander? Transl Androl Urol 5(6):898–908

Article  PubMed  PubMed Central  Google Scholar 

Lopez DS, Advani S, Tsilidis KK, Wang R, Canfield S (2017) Endogenous and exogenous testosterone and prostate cancer: decreased-, increased-or null-risk? Trans Androl Urol 6(3):566–579

Article  Google Scholar 

Lopez D, Qiu X, Advani S et al (2018) Double trouble: Co-occurrence of testosterone deficiency and body fatness associated with all-cause mortality in US men. Clin Endocrinol 88(1):58–65

Article  CAS  Google Scholar 

Morgentaler A 3rd, Conners WP (2015) Testosterone therapy in men with prostate cancer: literature review, clinical experience, and recommendations. Asian J Androl 17(2):206–211

Article  CAS  PubMed  PubMed Central  Google Scholar 

Platz EA (2008) Low testosterone and risk of premature death in older men: analytical and preanalytical issues in measuring circulating testosterone. Clin Chem 54(7):1110–1112

Article  CAS  PubMed  Google Scholar 

Araujo AB, Esche GR, Kupelian V et al (2007) Prevalence of symptomatic androgen deficiency in men. J Clin Endocrinol Metab 92(11):4241–4247

Article  CAS  PubMed  Google Scholar 

Travison TG, Araujo AB, O’Donnell AB, Kupelian V, McKinlay JB (2007) A population-level decline in serum testosterone levels in American men. J Clin Endocrinol Metab 92(1):196–202

Article  CAS  PubMed  Google Scholar 

Malik RD, Lapin B, Wang CE, Lakeman JC, Helfand BT (2015) Are we testing appropriately for low testosterone?: Characterization of tested men and compliance with current guidelines. J Sex Med 12(1):66–75

Article  PubMed  Google Scholar 

Rohrmann S, Shiels MS, Lopez DS et al (2011) Body fatness and sex steroid hormone concentrations in US men: results from NHANES III. Cancer Causes Control 22(8):1141–1151

Article  PubMed  Google Scholar 

Lopez DS, Peskoe SB, Joshu CE et al (2013) Racial/ethnic differences in serum sex steroid hormone concentrations in US adolescent males. Cancer Causes Control 24(4):817–826. https://doi.org/10.1007/s10552-013-0154-8

Article  PubMed  Google Scholar 

Rohrmann S, Nelson WG, Rifai N et al (2007) Serum estrogen, but not testosterone, levels differ between black and white men in a nationally representative sample of Americans. J Clin Endocrinol Metab 92(7):2519–2525

Article  CAS  PubMed  Google Scholar 

Erickson SE, Iribarren C, Tolstykh IV, Blanc PD, Eisner MD (2007) Effect of race on asthma management and outcomes in a large, integrated managed care organization. Arch Intern Med 167(17):1846–1852

Article  PubMed  Google Scholar 

Lederer DJ, Benn EK, Barr RG et al (2008) Racial differences in waiting list outcomes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 177(4):450–454

Article  PubMed  Google Scholar 

Omachi TA, Iribarren C, Sarkar U et al (2008) Risk factors for death in adults with severe asthma. Ann Allergy Asthma Immunol 101(2):130–136

Article  PubMed  PubMed Central  Google Scholar 

Centers for Disease Control and Prevention (CDC) National Center for Health Statistics. National Health and Nutrition Examination Survey: Overview. https://www.cdc.gov/nchs/nhanes/index.htm. Accessed Jun 2022

National Center for Health Statistics (1994) Plan and operation of the third national health and nutrition examination survey, 1988–94. series 1: programs and collection procedures. Vital Health Stat 1:1-407

Schnell K, Weiss CO, Lee T et al (2012) The prevalence of clinically-relevant comorbid conditions in patients with physician-diagnosed COPD: a cross-sectional study using data from NHANES 1999-2008. BMC Pulm Med 12:26. https://doi.org/10.1186/1471-2466-12-26

Article  PubMed  PubMed Central  Google Scholar 

Miller MR, Hankinson J, Brusasco V et al (2005) Standardisation of spirometry. Eur Respir J 26(2):319–338

Article  CAS  PubMed  Google Scholar 

Centers for Disease Control and Prevention (CDC) (2011) National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey (NHANES): Respiratory Health Spirometry Procedures Manual. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Hyattsville, MD

Google Scholar 

Mohamed Hoesein FAA, Zanen P, Lammers JWJ (2001) Lower limit of normal or FEV1/FVC <0.70 in diagnosing COPD: An evidence-based review. Respir Med 105(6):907–915. https://doi.org/10.1016/j.rmed.2011.01.008

Article  Google Scholar 

Hukkanen J, Jacob P, Benowitz NL (2005) Metabolism and disposition kinetics of nicotine. Pharmacol Rev 57(1):79–115

Article  CAS  PubMed  Google Scholar 

Menke A, Guallar E, Rohrmann S et al (2010) Sex steroid hormone concentrations and risk of death in US men. Am J Epidemiol 171(5):583–592

Article  PubMed  PubMed Central  Google Scholar 

Wu TD, Ejike CO, Wise RA, McCormack MC, Brigham EP (2019) Investigation of the obesity paradox in chronic obstructive pulmonary disease, according to smoking status, in the United States. Am J Epidemiol 188(11):1977–1983. https://doi.org/10.1093/aje/kwz185

Article  PubMed  PubMed Central  Google Scholar 

Mazur A (2009) The age-testosterone relationship in black, white, and Mexican-American men, and reasons for ethnic differences. Aging Male 12(2-3):66–76. https://doi.org/10.1080/13685530903071802

Article  CAS  PubMed  Google Scholar 

Aiyer A, Surani S, Aguillar R, Sharma M, Ali M, Varon J (2020) Ethnic variance in prevalence of COPD among smokers in a real world setting. Open Respir Med J 14:93–98. https://doi.org/10.2174/1874306402014010093

Article  PubMed  PubMed Central  Google Scholar 

Hardie G, Liu R, Darden J, Gold WM (2010) Ethnic differences in methacholine responsiveness and word descriptors in African Americans, Hispanic-Mexican Americans, Asian-Pacific Islanders, and Whites with mild asthma. J Asthma 47(4):388–396. https://doi.org/10.3109/02770903.2010.481341

Article  CAS  PubMed  Google Scholar 

Boen CE, Hummer RA (2019) Longer-but Harder-Lives?: the Hispanic health paradox and the social determinants of racial, ethnic, and immigrant-Native health disparities from midlife through late life. J Health Soc Behav 60(4):434–452. https://doi.org/10.1177/0022146519884538

Article  PubMed  PubMed Central  Google Scholar 

Pelusi C, Pasquali R (2012) The significance of low testosterone levels in obese men. Curr Obes Rep 1(4):181–190. https://doi.org/10.1007/s13679-012-0029-4

Article  Google Scholar 

Baillargeon J, Urban RJ, Zhang W et al (2019) Testosterone replacement therapy and hospitalization rates in men with COPD. Chron Respir Dis 16:1479972318793004. https://doi.org/10.1177/14799

Comments (0)

No login
gif