Thompson, D. J. et al. Genetic predisposition to mosaic Y chromosome loss in blood. Nature 575, 652–657 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Forsberg, L. A. et al. Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. Nat. Genet. 46, 624–628 (2014).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dumanski, J. P. et al. Mosaic loss of chromosome Y in blood is associated with Alzheimer disease. Am. J. Hum. Genet. 98, 1208–1219 (2016).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Duan, Q. et al. Mosaic loss of chromosome Y in peripheral blood cells is associated with age-related macular degeneration in men. Cell Biosci. 12, 73 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sano, S. et al. Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality. Science 377, 292–297 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haitjema, S. et al. Loss of Y chromosome in blood is associated with major cardiovascular events during follow-up in men after carotid endarterectomy. Circ. Cardiovasc. Genet. 10, e001544 (2017).

Article  CAS  PubMed  Google Scholar 

Sano, S., Thel, M. C. & Walsh, K. Mosaic loss of Y chromosome in white blood cells: its impact on men’s health. Physiology (Bethesda) 38, 161–166 (2023).

CAS  Google Scholar 

Dumanski, J. P. et al. Immune cells lacking Y chromosome show dysregulation of autosomal gene expression. Cell. Mol. Life Sci. 78, 4019–4033 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abdel-Hafiz, H. A. et al. Y chromosome loss in cancer drives growth by evasion of adaptive immunity. Nature 619, 624–631 (2023).

Article  CAS  PubMed  Google Scholar 

Mas-Peiro, S. et al. Mosaic loss of Y chromosome in monocytes is associated with lower survival after transcatheter aortic valve replacement. Eur. Heart J. 44, 1943–1952 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar