Zhang XM, Mitchell DG, Dohke M, et al. Pancreatic cysts: depiction on single-shot fast spin-echo MR images. Radiology. 2002;223:547–53.

Article  PubMed  Google Scholar 

Lee KS, Sekhar A, Rofsky NM, et al. Prevalence of incidental pancreatic cysts in the adult population on MR imaging. Am J Gastroenterol. 2010;105:2079–84.

Article  PubMed  Google Scholar 

Basturk O, Hong SM, Wood LD, et al. A revised classification system and recommendations from the baltimore consensus meeting for neoplastic precursor lesions in the pancreas. Am J Surg Pathol. 2015;39:1730–41.

Article  PubMed  PubMed Central  Google Scholar 

Adsay N, Fukushima N, Furukawa T, et al. Intraductal neoplasms of the pancreas. 4th ed. Lyon: WHO classification of tumors of the digestive system; 2010.

Google Scholar 

Oyama H, Tada M, Takagi K, et al. Long-term risk of malignancy in branch-duct intraductal papillary mucinous neoplasms. Gastroenterology. 2020;158(226–37): e225.

Google Scholar 

Iwashita T, Nakai Y, Samarasena JB, et al. High single-pass diagnostic yield of a new 25-gauge core biopsy needle for EUS-guided FNA biopsy in solid pancreatic lesions. Gastrointest Endosc. 2013;77:909–15.

Article  PubMed  Google Scholar 

Iwashita T, Yasuda I, Doi S, et al. Use of samples from endoscopic ultrasound-guided 19-gauge fine-needle aspiration in diagnosis of autoimmune pancreatitis. Clin Gastroenterol Hepatol. 2012;10:316–22.

Article  PubMed  Google Scholar 

Tomoda T, Kato H, Fujii Y, et al. Randomized trial comparing the 25G and 22G Franseen needles in endoscopic ultrasound-guided tissue acquisition from solid pancreatic masses for adequate histological assessment. Dig Endosc. 2022;34:596–603.

Article  PubMed  Google Scholar 

Kanno A, Miwata T, Nagai H, et al. Endoscopic ultrasound-guided pancreatic sampling for the histopathological diagnosis of autoimmune pancreatitis. Dig Endosc. 2022;34:420–7.

Article  PubMed  Google Scholar 

Ashida R, Kitano M. Endoscopic ultrasound-guided tissue acquisition for pancreatic ductal adenocarcinoma in the era of precision medicine. Dig Endosc. 2022;34:1329–39.

Article  PubMed  Google Scholar 

Ikeda G, Hijioka S, Nagashio Y, et al. Fine-needle biopsy with 19G needle is effective in combination with endoscopic ultrasound-guided tissue acquisition for genomic profiling of unresectable pancreatic cancer. Dig Endosc. 2023;35:124–33.

Article  PubMed  Google Scholar 

Iwashita T, Uemura S, Mita N, et al. Utility of endoscopic ultrasound and endoscopic ultrasound-guided fine-needle aspiration for the diagnosis and management of pancreatic cystic lesions: differences between the guidelines. Dig Endosc. 2020;32:251–62.

Article  PubMed  Google Scholar 

Brugge WR, Lewandrowski K, Lee-Lewandrowski E, et al. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology. 2004;126:1330–6.

Article  PubMed  Google Scholar 

Thosani N, Thosani S, Qiao W, et al. Role of EUS-FNA-based cytology in the diagnosis of mucinous pancreatic cystic lesions: a systematic review and meta-analysis. Dig Dis Sci. 2010;55:2756–66.

Article  PubMed  PubMed Central  Google Scholar 

Olar MP, Bolboaca SD, Pojoga C, et al. Clinical utility of the contrast-enhanced endoscopic ultrasound guided fine needle aspiration in the diagnosis of pancreatic cyst. Diagnostics. 2022;12:2209.

Article  PubMed  PubMed Central  Google Scholar 

Leung KK, Ross WA, Evans D, et al. Pancreatic cystic neoplasm: the role of cyst morphology, cyst fluid analysis, and expectant management. Ann Surg Oncol. 2009;16:2818–24.

Article  PubMed  Google Scholar 

Bick BL, Enders FT, Levy MJ, et al. The string sign for diagnosis of mucinous pancreatic cysts. Endoscopy. 2015;47:626–31.

Article  PubMed  Google Scholar 

van der Waaij LA, van Dullemen HM, Porte RJ. Cyst fluid analysis in the differential diagnosis of pancreatic cystic lesions: a pooled analysis. Gastrointest Endosc. 2005;62:383–9.

Article  PubMed  Google Scholar 

Faias S, Cravo MM, Chaves P, et al. A comparative analysis of glucose and carcinoembryonic antigen in diagnosis of pancreatic mucinous cysts: a systematic review and meta-analysis. Gastrointest Endosc. 2021;S0016–5107(21):00048–51.

Google Scholar 

Ribaldone DG, Bruno M, Gaia S, et al. Differential diagnosis of pancreatic cysts: a prospective study on the role of intra-cystic glucose concentration. Dig Liver Dis. 2020;52:1026–32.

Article  CAS  PubMed  Google Scholar 

McCarty TR, Garg R, Rustagi T. Pancreatic cyst fluid glucose in differentiating mucinous from nonmucinous pancreatic cysts: a systematic review and meta-analysis. Gastrointest Endosc. 2021;94(698–712): e696.

Google Scholar 

Gorris M, Dijk F, Farina A, et al. Validation of combined carcinoembryonic antigen and glucose testing in pancreatic cyst fluid to differentiate mucinous from non-mucinous cysts. Surg Endosc. 2023;37:3739–46.

Article  PubMed  PubMed Central  Google Scholar 

Nikiforova MN, Khalid A, Fasanella KE, et al. Integration of KRAS testing in the diagnosis of pancreatic cystic lesions: a clinical experience of 618 pancreatic cysts. Mod Pathol. 2013;26:1478–87.

Article  CAS  PubMed  Google Scholar 

Singhi AD, Nikiforova MN, Fasanella KE, et al. Preoperative GNAS and KRAS testing in the diagnosis of pancreatic mucinous cysts. Clin Cancer Res. 2014;20:4381–9.

Article  CAS  PubMed  Google Scholar 

Singhi AD, McGrath K, Brand RE, et al. Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia. Gut. 2018;67:2131–41.

Article  CAS  PubMed  Google Scholar 

Jones M, Zheng Z, Wang J, et al. Impact of next-generation sequencing on the clinical diagnosis of pancreatic cysts. Gastrointest Endosc. 2016;83:140–8.

Article  PubMed  Google Scholar 

Paniccia A, Polanco PM, Boone BA, et al. Prospective, multi-institutional, real-time next-generation sequencing of pancreatic cyst fluid reveals diverse genomic alterations that improve the clinical management of pancreatic cysts. Gastroenterology. 2023;164(117–33): e117.

Article  Google Scholar 

Furukawa T, Hatori T, Fujita I, et al. Prognostic relevance of morphological types of intraductal papillary mucinous neoplasms of the pancreas. Gut. 2011;60:509–16.

Article  PubMed  Google Scholar 

Maker AV, Katabi N, Gonen M, et al. Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas. Ann Surg Oncol. 2011;18:199–206.

Article  PubMed  Google Scholar 

Henry JC, Bassi C, Giovinazzo F, et al. MicroRNA from pancreatic duct aspirate differentiates cystic lesions of the pancreas. Ann Surg Oncol. 2013;20:S661–6.

Article  PubMed  Google Scholar 

Utomo WK, Looijenga LH, Bruno MJ, et al. A microRNA panel in pancreatic cyst fluid for the risk stratification of pancreatic cysts in a prospective cohort. Mol Ther Nucleic Acids. 2016;5: e350.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shirakami Y, Iwashita T, Uemura S, et al. Micro-RNA analysis of pancreatic cyst fluid for diagnosing malignant transformation of intraductal papillary mucinous neoplasm by comparing intraductal papillary mucinous adenoma and carcinoma. J Clin Med. 2021;10:2249.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Morgell A, Reisz JA, Ateeb Z, et al. Metabolic characterization of plasma and cyst fluid from cystic precursors to pancreatic cancer patients reveal metabolic signatures of bacterial infection. medRxiv. 2020;20:2725–38.

Google Scholar 

Ke E, Patel BB, Liu T, et al. Proteomic analyses of pancreatic cyst fluids. Pancreas. 2009;38:e33-42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aparicio JR, Martinez J, Niveiro M, et al. Direct intracystic biopsy and pancreatic cystoscopy through a 19-gauge needle EUS (with videos). Gastrointest Endosc. 2010;72:1285–8.

Article  PubMed  Google Scholar 

Yang D, Trindade AJ, Yachimski P, et al. Histologic analysis of endoscopic ultrasound-guided through the needle microforceps biopsies accurately identifies mucinous pancreas cysts. Clin Gastroenterol Hepatol. 2019;17:1587–96.

Article  PubMed  Google Scholar 

Samarasena JB, Nakai Y, Shinoura S, et al. EUS-guided, through-the-needle forceps biopsy: a novel tissue acquisition technique. Gastrointest Endosc. 2015;81:225–6.

Article  PubMed  Google Scholar 

Tacelli M, Celsa C, Magro B, et al. Diagnostic performance of endoscopic ultrasound through-the-needle microforceps biopsy of pancreatic cystic lesions: systematic review with meta-analysis. Dig Endosc. 2020;32:1018–30.

Article  PubMed  Google Scholar 

Rift CV, Melchior LC, Kovacevic B, et al. Targeted next-generation sequencing of EUS-guided through-the-needle-biopsy sampling from pancreatic cystic lesions. Gastrointest Endosc. 2023;97(50–8): e54.

Google Scholar 

Nakai Y, Iwashita T, Park DH, et al. Diagnosis of pancreatic cysts: EUS-guided, through-the-needle confocal laser-induced endomicroscopy and cystoscopy trial: DETECT study. Gastrointest Endosc. 2015;81:1204–14.

Article  PubMed  Google Scholar 

Napoleon B, Palazzo M, Lemaistre AI, et al. Needle-based confocal laser endomicroscopy of pancreatic cystic lesions: a prospective multicenter validation study in patients with definite diagnosis. Endoscopy. 2019;51:825–35.

Article  PubMed  Google Scholar 

Konda VJ, Meining A, Jamil LH, et al. A pilot study of in vivo identification of pancreatic cystic neoplasms with needle-based confocal laser endomicroscopy under endosonographic guidance. Endoscopy. 2013;45:1006–13.

Article