This communication highlights the significance of the final pH of the solution and the potential instability of deep eutectic solvent (DES) within aqueous solutions, and introducing a challenging aspect regarding solute solubilization by DESs.

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

The authors would like to thank Vice Chancellor for Research of Tabriz University of Medical Sciences for the financial support (72772) of the project.

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