3D-printed prednisolone phosphate suppositories with tunable dose and rapid release for the treatment of inflammatory bowel disease
Keywords
Fused deposition modeling
Hot-melt extrusion
Rectal administration
Infill density
Personalized medicine
AbbreviationsPSP
prednisolone sodium phosphate
HPC
hydroxypropyl cellulose
IBD
inflammatory bowel disease
FDM
fused deposition modeling
TGA
thermogravimetric analysis
DSC
differential scanning calorimetry
PXRD
powder X-ray diffraction, SEM, scanning electron microscopy
UPLC
ultra-performance liquid chromatography
Data availability
Data will be made available on request.
© 2023 The Author(s). Published by Elsevier B.V.
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