17-year follow-up of association between telomere length and all-cause mortality, cardiovascular mortality in individuals with metabolic syndrome: results from the NHANES database prospective cohort study

Pammer LM, Lamina C, Schultheiss UT, Kotsis F, Kollerits B, Stockmann H, Lipovsek J, Meiselbach H, Busch M, Eckardt KU, et al. Association of the metabolic syndrome with mortality and major adverse cardiac events: a large chronic Kidney Disease cohort. J INTERN MED. 2021;290(6):1219–32.

Article  CAS  PubMed  Google Scholar 

Kim TE, Kim H, Sung J, Kim DK, Lee MS, Han SW, Kim HJ, Kim SH, Ryu KH. The association between metabolic syndrome and Heart Failure in middle-aged male and female: Korean population-based study of 2 million individuals. Epidemiol Health. 2022;44:e2022078.

Article  PubMed  PubMed Central  Google Scholar 

Hirode G, Wong RJ. Trends in the prevalence of metabolic syndrome in the United States, 2011–2016. JAMA. 2020;323(24):2526–8.

Article  PubMed  PubMed Central  Google Scholar 

Mongraw-Chaffin M, Foster MC, Anderson C, Burke GL, Haq N, Kalyani RR, Ouyang P, Sibley CT, Tracy R, Woodward M, et al. Metabolically Healthy Obesity, transition to metabolic syndrome, and Cardiovascular Risk. J AM COLL CARDIOL. 2018;71(17):1857–65.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li D, Wang L, Zhou Z, Song L, Chen S, Yang Y, Hu Y, Wang Y, Wu S, Tian Y. Lifetime risk of Cardiovascular Disease and life expectancy with and without Cardiovascular Disease according to changes in metabolic syndrome status. Nutr Metab Cardiovasc Dis. 2022;32(2):373–81.

Article  CAS  PubMed  Google Scholar 

Schneider CV, Schneider KM, Teumer A, Rudolph KL, Hartmann D, Rader DJ, Strnad P. Association of Telomere length with risk of Disease and Mortality. JAMA INTERN MED. 2022;182(3):291–300.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khalangot MD, Krasnienkov DS, Chizhova VP, Korkushko OV, Shatilo VB, Kukharsky VM, Kravchenko VI, Kovtun VA, Guryanov VG, Vaiserman AM. Additional impact of glucose tolerance on telomere length in persons with and without metabolic syndrome in the Elderly Ukraine Population. Front Endocrinol (Lausanne). 2019;10:128.

Article  PubMed  Google Scholar 

Fasching CL. Telomere length measurement as a clinical biomarker of aging and Disease. Crit Rev Clin Lab Sci. 2018;55(7):443–65.

Article  CAS  PubMed  Google Scholar 

Huzen J, Wong LS, van Veldhuisen DJ, Samani NJ, Zwinderman AH, Codd V, Cawthon RM, Benus GF, van der Horst IC, Navis G, et al. Telomere length loss due to Smoking and metabolic traits. J INTERN MED. 2014;275(2):155–63.

Article  CAS  PubMed  Google Scholar 

Arbeev KG, Verhulst S, Steenstrup T, Kark JD, Bagley O, Kooperberg C, Reiner AP, Hwang SJ, Levy D, Fitzpatrick AL, et al. Association of leukocyte telomere length with mortality among adult participants in 3 longitudinal studies. JAMA Netw Open. 2020;3(2):e200023.

Article  PubMed  PubMed Central  Google Scholar 

Chen Z, Shen Y, He J, Shen Y, Zhu W, Wu X, Xiao M. Longer leukocyte telomere length increases cardiovascular mortality in type 2 Diabetes patients. J DIABETES. 2023;15(4):325–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Revesz D, Milaneschi Y, Verhoeven JE, Penninx BW. Telomere length as a marker of cellular aging is associated with prevalence and progression of metabolic syndrome. J Clin Endocrinol Metab. 2014;99(12):4607–15.

Article  CAS  PubMed  Google Scholar 

Revesz D, Verhoeven JE, Picard M, Lin J, Sidney S, Epel ES, Penninx B, Puterman E. Associations between Cellular aging markers and metabolic syndrome: findings from the CARDIA Study. J Clin Endocrinol Metab. 2018;103(1):148–57.

Article  PubMed  Google Scholar 

Loh NY, Rosoff D, Noordam R, Christodoulides C. Investigating the impact of metabolic syndrome traits on telomere length: a mendelian randomization study. Obes (Silver Spring). 2023;31(8):2189–98.

Article  CAS  Google Scholar 

Loh NY, Noordam R, Christodoulides C. Telomere length and metabolic syndrome traits: a mendelian randomisation study. Aging Cell. 2021;20(8):e13445.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang X, Guo Y, Yao N, Wang L, Sun M, Xu X, Yang H, Sun Y, Li B. Association between dietary inflammatory index and metabolic syndrome: analysis of the NHANES 2005–2016. Front Nutr. 2022;9:991907.

Article  PubMed  PubMed Central  Google Scholar 

Ogletree SS, Huang JH, Reif D, Yang L, Dunstan C, Osakwe N, Oh JI, Hipp JA. The relationship between greenspace exposure and telomere length in the National Health and Nutrition Examination Survey. SCI TOTAL ENVIRON. 2023;905:167452.

Article  CAS  PubMed  Google Scholar 

Needham BL, Rehkopf D, Adler N, Gregorich S, Lin J, Blackburn EH, Epel ES. Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999–2002. EPIDEMIOLOGY. 2015;26(4):528–35.

Article  PubMed  PubMed Central  Google Scholar 

Fan H, Wang Y, Ren Z, Liu X, Zhao J, Yuan Y, Fei X, Song X, Wang F, Liang B. Mediterranean diet lowers all-cause and cardiovascular mortality for patients with metabolic syndrome. DIABETOL METAB SYNDR. 2023;15(1):107.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shen T, Bimali M, Faramawi M, Orloff MS. Consumption of Vitamin K and vitamin a are Associated with reduced risk of developing Emphysema: NHANES 2007–2016. Front Nutr. 2020;7:47.

Article  PubMed  PubMed Central  Google Scholar 

Goyal R, Kumar A, Singhai M. Study of metabolic syndrome and its risk components in patients attending tertiary care center of uttarakhand. Indian J Clin Biochem. 2014;29(3):362–6.

Article  CAS  PubMed  Google Scholar 

Blackburn EH, Epel ES, Lin J. Human telomere biology: a contributory and interactive factor in aging, Disease risks, and protection. Science. 2015;350(6265):1193–8.

Article  CAS  PubMed  Google Scholar 

Gavia-Garcia G, Rosado-Perez J, Arista-Ugalde TL, Aguiniga-Sanchez I, Santiago-Osorio E, Mendoza-Nunez VM. Telomere length and oxidative stress and its relation with metabolic Syndrome Components in the aging. Biology (Basel) 2021, 10(4).

Willeit P, Willeit J, Kloss-Brandstatter A, Kronenberg F, Kiechl S. Fifteen-year follow-up of association between telomere length and incident cancer and cancer mortality. JAMA. 2011;306(1):42–4.

Article  CAS  PubMed  Google Scholar 

Adegunsoye A, Newton CA, Oldham JM, Ley B, Lee CT, Linderholm AL, Chung JH, Garcia N, Zhang D, Vij R, et al. Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts. NAT COMMUN. 2023;14(1):1489.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rattan P, Penrice DD, Ahn JC, Ferrer A, Patnaik M, Shah VH, Kamath PS, Mangaonkar AA, Simonetto DA. Inverse Association of Telomere length with Liver Disease and Mortality in the US Population. Hepatol Commun. 2022;6(2):399–410.

Article  CAS  PubMed  Google Scholar 

Chen L, Yin X, Zhao Y, Chen H, Tan T, Yao P, Tang Y. Biological ageing and the risks of all-cause and cause-specific mortality among people with Diabetes: a prospective cohort study. J Epidemiol Community Health. 2022;76(9):771–8.

Article  PubMed  Google Scholar 

Kodali HP, Borrell LN. Telomere length and mortality risk among adults in the United States: the role of age and race and ethnicity. ANN EPIDEMIOL. 2021;63:68–74.

Article  PubMed  Google Scholar 

Subedi P, Nembrini S, An Q, Zhu Y, Peng H, Yeh F, Cole SA, Rhoades DA, Lee ET, Zhao J. Telomere length and cancer mortality in American indians: the strong heart study. GEROSCIENCE. 2019;41(3):351–61.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martinez P, Blasco MA. Heart-breaking telomeres. CIRC RES. 2018;123(7):787–802.

Article  CAS  PubMed  Google Scholar 

Margaritis M, Sanna F, Lazaros G, Akoumianakis I, Patel S, Antonopoulos AS, Duke C, Herdman L, Psarros C, Oikonomou EK, et al. Predictive value of telomere length on outcome following acute Myocardial Infarction: evidence for contrasting effects of vascular vs. blood oxidative stress. EUR HEART J. 2017;38(41):3094–104.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ospanov O, Akilzhanova A, Buchwald JN, Fursov A, Bekmurzinova F, Rakhimova S, Yeleuov G, Kozhamkulov U, Abdina Z, Fursov R, et al. Stapleless vs stapled gastric bypass vs Hypocaloric Diet: a three-arm randomized controlled trial of body Mass Evolution with secondary outcomes for telomere length and metabolic syndrome changes. OBES SURG. 2021;31(7):3165–76.

Article  PubMed  Google Scholar 

Fernandez-Alvira JM, Fuster V, Dorado B, Soberon N, Flores I, Gallardo M, Pocock S, Blasco MA, Andres V. Short Telomere load, telomere length, and subclinical Atherosclerosis: the PESA Study. J AM COLL CARDIOL. 2016;67(21):2467–76.

Article  CAS  PubMed  Google Scholar 

Fathi E, Charoudeh HN, Sanaat Z, Farahzadi R. Telomere shortening as a hallmark of stem cell senescence. Stem Cell Investig. 2019;6:7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Revesz D, Milaneschi Y, Verhoeven JE, Lin J, Penninx BW. Longitudinal associations between metabolic Syndrome Components and Telomere Shortening. J Clin Endocrinol Metab. 2015;100(8):3050–9.

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