It will take action, commitment, require significant investment, and it depends on a sustained and multifaceted approach that includes reducing the unnecessary use of antimicrobial drugs in human and animal health, and agriculture. 

This can be achieved through the implementation of effective infection prevention and control measures, such as hand hygiene, better access to clean water, development of diagnostics to aid antimicrobial stewardship, improved investment and uptake of vaccines, and careful controlled use of the effective antibiotics that we are currently relying on.