Volume 208, January 2024, Pages 1-4Author links open overlay panel, , , , Abstract

Fibromatosis, or desmoid tumour, is characterized by excessive and infiltrative proliferation of connective tissue originating from aponeurotic muscle structures. Mammary fibromatosis is rare in humans and animals and its precise aetiology is unknown. A 10-year-old mixed-breed female dog developed a mass in the right cranial thoracic mammary gland (M1) and underwent lumpectomy. The mass was firm, with an irregular surface and distinct limits. Microscopically, it was a neoplastic proliferation of fusiform cells with low atypia, interspersed with abundant dense collagenous tissue, confirmed by histochemical staining with Gomori's trichrome and Masson's trichrome and immunopositivity for vimentin and smooth muscle actin, confirming mammary fibromatosis. Mammary fibromatosis in dogs needs further studies to elucidate its clinical, epidemiological and aetiopathogenic aspects.

Section snippetsFunding

This work was financially supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Fundaçāo de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG) (Rede Mineira de Pesquisa Translacional em Imunobiológicos e Biofármacos no Câncer [REMITRIBIC, RED-00031-21]) and Coordenaçāo de Aperfeiçoamento Pessoal de Nível Superior (CAPES), Brazil.

Statement of author contributions

M.P. dos Reys, K.Y. Nakagaki, G.D. Cassali: Writing – reviewing and editing. G.D. Cassali, L.A.B. Borges, F.R. Souza: Microscopic analysis of the mammary sample.

Declaration of competing interests

The authors declared no conflicts of interest in relation to the research, authorship or publication of this article.

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