Bovee J. Multiple osteochondromas. Orphanet J Rare Dis. 2008;3:3.

Article  PubMed  PubMed Central  Google Scholar 

Hameetman L, Bovée JVMG, Taminiau AHM, Kroon HM, Hogendoorn PCW. Multiple osteochondromas: clinicopathological and genetic spectrum and suggestions for clinical management. Hered Cancer Clin Pract. 2004;2:161–73.

Article  PubMed  PubMed Central  Google Scholar 

Wuyts W, Schmale G, Chansky H, Raskind W. Hereditary multiple osteochondromas. In: Adam MP, Everman DB, Mirzaa GM, et al., editors. GeneReviews Seattle (WA). Seattle: University of Washington; 2020. p. 1993–2023.

Google Scholar 

Alvarez A, Tredwell S, De Vera M, Hayden M. The genotype-phenotype correlation of hereditary multiple exostoses. Clin Genet. 2006;70:122–30.

Article  CAS  PubMed  Google Scholar 

Pedrini E, Jennes I, Tremosini M, et al. Genotype-phenotype correlation study in 529 patients with multiple hereditary exostoses: identification of “protective” and “risk” factors. J Bone Joint Surg Am. 2011;93:2294–302.

Article  PubMed  Google Scholar 

Porter DE, Lonie L, Fraser M, et al. Severity of disease and risk of malignant change in hereditary multiple exostoses. A genotype-phenotype study. J Bone Joint Surg Br. 2004;86B:1041–6.

Article  Google Scholar 

Ham SJ. Multiple hereditary exostoses: clinical problems and therapeutic options – genetic disorders. Orthop Trauma. 2013;27:118–25.

Article  Google Scholar 

Murphy M, Choi J, Kransdorf M, Flemming D, Gannon F. Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics. 2000;20:1407–34.

Article  Google Scholar 

Darilek S, Wicklund C, Novy D, et al. Hereditary multiple exostosis and pain. J Pediatr Orthop. 2005;25:369–76.

Article  PubMed  Google Scholar 

Goud AL, de Lange J, Scholtes VA, Bulstra SW, Ham SJ. Pain, physical and social functioning and quality of life in individuals with hereditary multiple exostoses in the Netherlands: a national cohort study. J Bone Joint Surg Am. 2012;94A:1013–20.

Article  Google Scholar 

Czajka C, DiCaprio M. What is the proportion of patients with multiple hereditary exostoses who undergo malignant degeneration? Clin Orthop Relat Res. 2015;473:2355–61.

Article  PubMed  PubMed Central  Google Scholar 

Jurik AG, Holmberg P, Mortensen M. Whole-body MRI in assessing malignant transformation in multiple hereditary exostoses and enchondromatosis: audit results and literature review. Skeletal Radiol. 2020;49:115–24.

Article  PubMed  Google Scholar 

Ahmed AR, Tan T-S, Unni KK, et al. Secondary chondrosarcoma in osteochondroma: report of 107 cases. Clin Orthop. 2003;411:193–206.

Article  Google Scholar 

Sonne-Holm E, Wong C, Sonne-Holm S. Multiple cartilaginous exostoses and development of chondrosarcomas – a systematic review. Dan Med J. 2014;61(9):A4895.

PubMed  Google Scholar 

Bernard SA, Murphy MD, Flemming DJ, Kransdorf MJ. Improved differentiation of benign osteochondromas from secondary chondrosarcomas with standardized measurement of cartilage cap at CT and MR imaging. Radiology. 2010;255:857–65.

Article  PubMed  Google Scholar 

Fei L, Ngoh C, Porter D. Chondrosarcoma transformation in hereditary multiple exostoses: a systematic review and clinical and cost-effectiveness of a proposed screening model. J Bone Oncol. 2018;13:114–22.

Article  PubMed  PubMed Central  Google Scholar 

Hendel HW, Daugaard S, Kjaer A. Utility of planar bone scintigraphy to distinguish benign osteochondromas from malignant chondrosarcomas. Clin Nucl Med. 2002;27:622–4.

Article  PubMed  Google Scholar 

Feldman F, Van Heertum R, Parisien SC, M. 18FDG-PET Applications for cartilage neoplasms. Skeletal Radiol. 2005;34:367–74.

Article  PubMed  Google Scholar 

Purandare NC, Puranik A, Shas S, et al. Nucl Med Commun. 2019;40:645–51.

Article  PubMed  Google Scholar 

Sambaziotis C, Lovy A, Moadel R, et al. Fluorine-18 fluorodeoxyglucose positron emission tomography for osteochondromas utilizing a triple-time point protocol. Open J Med Imaging. 2011;1:15–20.

Article  Google Scholar 

Van der Woude HJ, Van der Zwan AL, Flipsen M, Welsink C, Ham SJ. Concurrent intraosseous cartilaginous lesions in patients with multiple osteochondromas (MO) identified on total body MR imaging. Skeletal Radiol. 2023;52(7):1369–75.

Article  PubMed  Google Scholar 

Goud A, Wuyts W, Bessems J, Bramer J, Van der Woude HJ, Ham J. Intraosseous atypical chondroid tumor or chondrosarcoma grade 1 in patients with multiple osteochondromas. J Bone Joint Surg Am. 2015;97:24–31.

Article  PubMed  Google Scholar 

Jackson T, Shah A, Arkader A. Is routine spine MRI necessary in skeletally immature patients with MHE? Identifying patients at risk for spinal osteochondromas. J Pediatr Orthop. 2019;39:147–52.

Article  Google Scholar 

Roach J, Klatt J, Faulkner N. Involvement of the spine in patients with multiple hereditary exostoses. J Bone Joint Surg Am. 2009;91:1942–8.

Article  PubMed  Google Scholar 

Albrecht S, Crutchfield J. SeGall G On spinal osteochondromas. J Neurosurg. 1992;77:247–52.

Article  CAS  PubMed  Google Scholar 

Ashraf A, Larson N, Ferski G, Mielke C, Wetjen N. Guidera K Spinal stenosis frequent in children with multiple hereditary exostoses. J Child Orthop. 2013;7:183–94.

Article  PubMed  PubMed Central  Google Scholar 

Montgomery B, Cohen E, Frick S. Spinal screening MRI trends in patients with multiple hereditary exostoses: national survey. Cureus. 2019;11:e6452.

PubMed  PubMed Central  Google Scholar