Yang L, Fujimoto J (2015) Childhood cancer mortality in Japan, 1980–2013. BMC Cancer 15:446

Article  PubMed  PubMed Central  Google Scholar 

Nakata K, Ito Y, Magadi W, Bonaventure A, Stiller C, Katanoda K, Matsuda T, Miyashiro I, Pritchard-Jones K, Rachet B (2018) Childhood cancer incidence and survival in Japan and England: a population-based study (1993–2010). Cancer Sci 109:422–434

Article  CAS  PubMed  Google Scholar 

Reulen RC, Winter DL, Frobisher C, Lancashire ER, Stiller CA, Jenney ME, Skinner R, Stevens MC, Hawkins MM, British Childhood Cancer Survivor Study Steering Group (2010) Long-term cause-specific mortality among survivors of childhood cancer. JAMA 304:172–179

Article  CAS  PubMed  Google Scholar 

Fornaro A, Olivotto I, Rigacci L, Ciaccheri M, Tomberli B, Ferrantini C, Coppini R, Girolami F, Mazzarotto F, Chiostri M, Milli M, Marchionni N, Castelli G (2018) Comparison of long-term outcome in anthracycline-related versus idiopathic dilated cardiomyopathy: a single centre experience. Eur J Heart Fail 20:898–906

Article  CAS  PubMed  Google Scholar 

Cardinale D, Colombo A, Lamantia G, Colombo N, Civelli M, De Giacomi G, Rubino M, Veglia F, Fiorentini C, Cipolla CM (2010) Anthracycline-induced cardiomyopathy: clinical relevance and response to pharmacologic therapy. J Am Coll Cardiol 55:213–220

Article  CAS  PubMed  Google Scholar 

Cardinale D, Colombo A, Bacchiani G, Tedeschi I, Meroni CA, Veglia F, Civelli M, Lamantia G, Colombo N, Curigliano G, Fiorentini C, Cipolla CM (2015) Early detection of anthracycline cardiotoxicity and improvement with heart failure therapy. Circulation 131:1981–1988

Article  CAS  PubMed  Google Scholar 

Negishi K, Negishi T, Haluska BA, Hare JL, Plana JC, Marwick TH (2014) Use of speckle strain to assess left ventricular responses to cardiotoxic chemotherapy and cardioprotection. Eur Heart J Cardiovasc Imag 15:324–331

Article  Google Scholar 

van der Pal HJ, van Dalen EC, van Delden E, van Dijk IW, Kok WE, Geskus RB, Sieswerda E, Oldenburger F, Koning CC, van Leeuwen FE, Caron HN, Kremer LC (2012) High risk of symptomatic cardiac events in childhood cancer survivors. J Clin Oncol 30:1429–1437

Article  PubMed  Google Scholar 

Tuzovic M, Wu PT, Kianmahd S, Nguyen KL (2018) Natural history of myocardial deformation in children, adolescents, and young adults exposed to anthracyclines: Systematic review and meta-analysis. Echocardiography 35:922–934

Article  PubMed  PubMed Central  Google Scholar 

Cho JS, Shrestha S, Kagiyama N, Hu L, Ghaffar YA, Casaclang-Verzosa G, Zeb I, Sengupta PP (2020) A network-based “phenomics” approach for discovering patient subtypes from high-throughput cardiac imaging data. JACC Cardiovasc Imag 13:1655–1670

Article  Google Scholar 

Matsuura K, Shiraishi K, Sato K, Shimada K, Goya S, Uemura A, Ifuku M, Iso T, Takahashi K, Tanaka R (2019) Left ventricular vortex and intraventricular pressure difference in dogs under various loading conditions. Am J Physiol Heart Circ Physiol 316:H882–H888

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsuura K, Shiraishi K, Mandour AS, Sato K, Shimada K, Goya S, Yoshida T, Kitpipatkun P, Hamabe L, Uemura A, Yilmaz Z, Ifuku M, Iso T, Takahashi K, Tanaka R (2021) The utility of intraventricular pressure gradient for early detection of chemotherapy-induced subclinical cardiac dysfunction in dogs. Animals (Basel) 11:1122

Article  PubMed  Google Scholar 

Iwano H, Kamimura D, Fox E, Hall M, Vlachos P, Little WC (2015) Altered spatial distribution of the diastolic left ventricular pressure difference in heart failure. J Am Soc Echocardiogr 28:597-605.e591

Article  PubMed  PubMed Central  Google Scholar 

Tsujinaga S, Iwano H, Sarashina M, Hayashi T, Murayama M, Ichikawa A, Nakabachi M, Nishino H, Yokoyama S, Fukushima A, Yokota T, Okada K, Kaga S, Vlachos PP, Anzai T (2019) Diastolic intra-left ventricular pressure difference during exercise: strong determinant and predictor of exercise capacity in patients with heart failure. J Card Fail 25:268–277

Article  PubMed  Google Scholar 

Chiba Y, Iwano H, Tsuneta S, Tsujinaga S, Meyers B, Vlachos P, Ishizaka S, Motoi K, Aoyagi H, Tamaki Y, Tanemura A, Murayama M, Yokoyama S, Nakabachi M, Nishino H, Kaga S, Kamiya K, Ohira H, Tsujino I, Anzai T (2022) Determinants of altered left ventricular suction in pre-capillary pulmonary hypertension. Eur Heart J Cardiovasc Imag 23:1399–1406

Article  Google Scholar 

Greenberg NL, Vandervoort PM, Firstenberg MS, Garcia MJ, Thomas JD (2001) Estimation of diastolic intraventricular pressure gradients by Doppler M-mode echocardiography. Am J Physiol Heart Circ Physiol 280:H2507-2515

Article  CAS  PubMed  Google Scholar 

Popović ZB, Richards KE, Greenberg NL, Rovner A, Drinko J, Cheng Y, Penn MS, Fukamachi K, Mal N, Levine BD, Garcia MJ, Thomas JD (2006) Scaling of diastolic intraventricular pressure gradients is related to filling time duration. Am J Physiol Heart Circ Physiol 291:H762-769

Article  PubMed  Google Scholar 

Yazaki K, Takahashi K, Shigemitsu S, Yamada M, Iso T, Kobayashi M, Akimoto K, Tamaichi H, Fujimura J, Saito M, Nii M, Shimizu T (2018) In-depth insight into the mechanisms of cardiac dysfunction in patients with childhood cancer after anthracycline treatment using layer-specific strain analysis. Circ J 82:715–723

Article  CAS  PubMed  Google Scholar 

Iso T, Takahashi K, Yazaki K, Ifuku M, Nii M, Fukae T, Yazawa R, Ishikawa A, Haruna H, Takubo N, Kurita M, Ikeda F, Watada H, Shimizu T (2019) In-depth insight into the mechanisms of cardiac dysfunction in patients with type 1 diabetes mellitus using layer-specific strain analysis. Circ J 83:1330–1337

Article  CAS  PubMed  Google Scholar 

Takahashi K, Nii M, Takigiku K, Toyono M, Iwashima S, Inoue N, Tanaka N, Matsui K, Shigemitsu S, Yamada M, Kobayashi M, Yazaki K, Itatani K, Shimizu T (2019) Development of suction force during early diastole from the left atrium to the left ventricle in infants, children, and adolescents. Heart Vessels 34:296–306

Article  PubMed  Google Scholar 

Shigemitsu S, Takahashi K, Yazaki K, Kobayashi M, Yamada M, Akimoto K, Tamaichi H, Fujimura J, Saito M, Nii M, Itatani K, Shimizu T (2019) New insight into the intraventricular pressure gradient as a sensitive indicator of diastolic cardiac dysfunction in patients with childhood cancer after anthracycline therapy. Heart Vessels 34:992–1001

Article  PubMed  Google Scholar 

Seidman A, Hudis C, Pierri MK, Shak S, Paton V, Ashby M, Murphy M, Stewart SJ (2002) Keefe D (2002) Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol 20:1215–1221

Article  CAS  PubMed  Google Scholar 

Llesuy SF, Milei J, Gonzalez Flecha BS, Boveris A (1990) Myocardial damage induced by doxorubicins: hydroperoxide-initiated chemiluminescence and morphology. Free Radic Biol Med 8:259–264

Article  CAS  PubMed  Google Scholar 

Milei J, Boveris A, Llesuy S, Molina HA, Storino R, Ortega D, Milei SE (1986) Amelioration of adriamycin-induced cardiotoxicity in rabbits by prenylamine and vitamins A and E. Am Heart J 111:95–102

Article  CAS  PubMed  Google Scholar 

Perel RD, Slaughter RE, Strugnell WE (2006) Subendocardial late gadolinium enhancement in two patients with anthracycline cardiotoxicity following treatment for Ewing’s sarcoma. J Cardiovasc Magn Reson 8:789–791

Article  PubMed  Google Scholar 

Sanchez-Quintana D, Anderson RH, Ho SY (1996) Ventricular myoarchitecture in tetralogy of Fallot. Heart 76:280–286

Article  CAS  PubMed  PubMed Central  Google Scholar 

Streeter DD Jr, Spotnitz HM, Patel DP, Ross J Jr, Sonnenblick EH (1969) Fiber orientation in the canine left ventricle during diastole and systole. Circ Res 24:339–347

Article  PubMed  Google Scholar 

Attias D, Macron L, Dreyfus J, Monin JL, Brochet E, Lepage L, Hekimian G, Iung B, Vahanian A, Messika-Zeitoun D (2013) Relationship between longitudinal strain and symptomatic status in aortic stenosis. J Am Soc Echocardiogr 26:868–874

Article  PubMed  Google Scholar 

Ohara T, Niebel CL, Stewart KC, Charonko JJ, Pu M, Vlalchos PP, Little WC (2012) Loss of adrenergic augmentation of diastolic intra-LV pressure difference in patients with diastolic dysfunction: evaluation by color M-mode echocardiography. JACC Cardiovasc Imag 5:861–870

Article  Google Scholar 

Steine K, Stugaard M, Smiseth OA (1999) Mechanisms of retarded apical filling in acute ischemic left ventricular failure. Circulation 99:2048–2054

Article  CAS  PubMed  Google Scholar 

Nikolic SD, Feneley MP, Pajaro OE, Rankin JS, Yellin EL (1995) Origin of regional pressure gradients in the left ventricle during early diastole. Am J Physiol 268:H550-557

CAS  PubMed  Google Scholar 

Firstenberg MS, Smedira NG, Greenberg NL, Prior DL, McCarthy PM, Garcia MJ, Thomas JD (2001) Relationship between early diastolic intraventricular pressure gradients, an index of elastic recoil, and improvements in systolic and diastolic function. Circulation 104:I330-335

Article  CAS  PubMed  Google Scholar 

Kremer LC, van Dalen EC, Offringa M, Ottenkamp J, Voûte PA (2001) Anthracycline-induced clinical heart failure in a cohort of 607 children: long-term follow-up study. J Clin Oncol 19:191–196

Article  CAS  PubMed  Google Scholar 

Feijen E, Font-Gonzalez A, Van der Pal HJH, Kok WEM, Geskus RB, Ronckers CM, Bresters D, van Dalen EC, van Dulmen-den Broeder E, van den Berg MH, van der Heiden-van der Loo M, van den Heuvel-Eibrink MM, van Leeuwen FE, Loonen JJ, Neggers Sjcmm, Versluys ABB, Tissing WJE, Kremer LCM (2019) Risk and temporal changes of heart failure among 5-year childhood cancer survivors: a DCOG-LATER Study. J Am Heart Assoc 8:e009122

Notomi Y, Martin-Miklovic MG, Oryszak SJ, Shiota T, Deserranno D, Popovic ZB, Garcia MJ, Greenberg NL, Thomas JD (2006) Enhanced ventricular untwisting during exercise: a mechanistic manifestation of elastic recoil described by Doppler tissue imaging. Circulation 113:2524–2533

Article  PubMed  Google Scholar 

Garcia MJ, Thomas JD, Klein AL (1998) New Doppler echocardiographic applications for the study of diastolic function. J Am Coll Cardiol 32:865–875

Article  CAS