Hypothyroidism can rarely lead to myopathy and pseudohypertrophy of calf muscles. Hypothyroidism-induced myositis is a type of inflammatory myopathy that causes proximal muscular weakness, fatigue, stiffness, myalgia/ tenderness, and delayed tendon reflexes. This condition can be confirmed by elevated levels of muscle enzymes like creatine kinase (up to 10 times the normal levels), nonspecific electromyographic (EMG) abnormalities, and pathological findings in muscle biopsy. Patients are usually treated with thyroid hormone and corticosteroids in some cases. It may take several months for muscle symptoms to resolve. In this case series, we present a comprehensive analysis of nine patients diagnosed with hypothyroid myositis, evaluating their clinical features, diagnostic workup, treatment outcomes, and follow-up.