Integrating ferroptosis-related genes (FRGs) and prognostic models to enhance UCEC outcome prediction and therapeutic insights

Abu-Zaid A, Alomar O, Abuzaid M, Baradwan S, Salem H, Al-Badawi IA (2021) Preoperative anemia predicts poor prognosis in patients with endometrial cancer: a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol 258:382–390

Article  PubMed  Google Scholar 

Argentiero A, Solimando AG, Krebs M, Leone P, Susca N, Brunetti O et al (2020) Anti-angiogenesis and immunotherapy: novel paradigms to envision tailored approaches in renal cell-carcinoma. J Clin Med 9(5):1594

Bednarz-Misa I, Fleszar MG, Fortuna P, Lewandowski L, Mierzchala-Pasierb M, Diakowska D et al (2021) Altered L-arginine metabolic pathways in gastric cancer: potential therapeutic targets and biomarkers. Biomolecules 11(8):1086

Bielfeld AP, Pour SJ, Poschmann G, Stuhler K, Krussel JS, Baston-Bust DM (2019)  A Proteome approach reveals differences between fertile women and patients with repeated implantation failure on endometrial level(-)does hCG render the endometrium of RIF patients? Int J Mol Sci 20(2):425

Brooks RA, Fleming GF, Lastra RR, Lee NK, Moroney JW, Son CH et al (2019) Current recommendations and recent progress in endometrial cancer. CA Cancer J Clin 69(4):258–279

Article  PubMed  Google Scholar 

Chen Y, Li H (2022) Prognostic and predictive models for left- and right- colorectal cancer patients: a bioinformatics analysis based on ferroptosis-related genes. Front Oncol 12:833834

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen X, Kang R, Kroemer G, Tang D (2021) Broadening horizons: the role of ferroptosis in cancer. Nat Rev Clin Oncol 18(5):280–296

Article  CAS  PubMed  Google Scholar 

Cheng T, Wu Y, Liu Z, Yu Y, Sun S, Guo M et al (2022) CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer. Front Immunol 13:970950

Article  CAS  PubMed  PubMed Central  Google Scholar 

de Queiroz RM, Moon SH, Prives C (2022) O-GlcNAc transferase regulates p21 protein levels and cell proliferation through the FoxM1-Skp2 axis in a p53-independent manner. J Biol Chem 298(9):102289

Article  PubMed  PubMed Central  Google Scholar 

Deng Y, Zhang F, Sun ZG, Wang S (2021) Development and validation of a prognostic signature associated with tumor microenvironment based on autophagy-related lncRNA analysis in hepatocellular carcinoma. Front Med (lausanne) 8:762570

Article  PubMed  Google Scholar 

Jiang P, Yang F, Zou C, Bao T, Wu M, Yang D et al (2021) The construction and analysis of a ferroptosis-related gene prognostic signature for pancreatic cancer. Aging (albany NY) 13(7):10396–10414

Article  CAS  PubMed  Google Scholar 

Liu J, Wang Y, Meng H, Yin Y, Zhu H, Ni T (2021) Identification of the prognostic signature associated with tumor immune microenvironment of uterine corpus endometrial carcinoma based on ferroptosis-related genes. Front Cell Dev Biol 9:735013

Article  PubMed  PubMed Central  Google Scholar 

Lortet-Tieulent J, Ferlay J, Bray F, Jemal A (2018) International patterns and trends in endometrial cancer incidence, 1978–2013. J Natl Cancer Inst 110(4):354–361

Article  PubMed  Google Scholar 

Ng SW, Norwitz SG, Taylor HS, Norwitz ER (2020) Endometriosis: the role of iron overload and ferroptosis. Reprod Sci 27(7):1383–1390

Article  CAS  PubMed  Google Scholar 

Steiner E, Eicher O, Sagemuller J, Schmidt M, Pilch H, Tanner B et al (2003) Multivariate independent prognostic factors in endometrial carcinoma: a clinicopathologic study in 181 patients: 10 years experience at the Department of Obstetrics and Gynecology of the Mainz University. Int J Gynecol Cancer 13(2):197–203

CAS  PubMed  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A et al (2021) Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209–249

Article  PubMed  Google Scholar 

Tao YF, Lu J, Du XJ, Sun LC, Zhao X, Peng L et al (2012) Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells. BMC Cancer 12:619

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang H, Peng S, Cai J, Bao S (2021a) Silencing of PTPN18 induced ferroptosis in endometrial cancer cells through p-p38-mediated GPX4/xCT down-regulation. Cancer Manag Res 13:1757–1765

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang H, Wu Y, Chen S, Hou M, Yang Y, Xie M (2021b) Construction and validation of a ferroptosis-related prognostic model for endometrial cancer. Front Genet 12:729046

Article  CAS  PubMed  PubMed Central  Google Scholar 

Weijiao Y, Fuchun L, Mengjie C, Xiaoqing Q, Hao L, Yuan L et al (2021) Immune infiltration and a ferroptosis-associated gene signature for predicting the prognosis of patients with endometrial cancer. Aging (albany NY) 13(12):16713–16732

Article  PubMed  Google Scholar 

Xiang Y, Lv D, Song T, Niu C, Wang Y (2022) Tumor suppressive role of microRNA-139-5p in bone marrow mesenchymal stem cells-derived extracellular vesicles in bladder cancer through regulation of the KIF3A/p21 axis. Cell Death Dis 13(7):599

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu W, Anwaier A, Liu W, Wei G, Su J, Tian X et al (2022) Genomic alteration of MTAP/CDKN2A predicts sarcomatoid differentiation and poor prognosis and modulates response to immune checkpoint blockade in renal cell carcinoma. Front Immunol 13:953721

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan Y, Cao W, Zhou H, Qian H, Wang H (2021) CLTRN, Regulated by NRF1/RAN/DLD protein complex, enhances radiation sensitivity of hepatocellular carcinoma cells through ferroptosis pathway. Int J Radiat Oncol Biol Phys 110(3):859–871

Article  PubMed  Google Scholar 

Zhang M, Zhang T, Song C, Qu J, Gu Y, Liu S et al (2021a) Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis. J Ethnopharmacol 274:114064

Article  CAS  PubMed  Google Scholar 

Zhang A, Yang J, Ma C, Li F, Luo H (2021b) Development and validation of a robust ferroptosis-related prognostic signature in lung adenocarcinoma. Front Cell Dev Biol 9:616271

Article  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif