The Impact of a Short-Term Ketogenic Low-Carbohydrate High-Fat Diet on Biomarkers of Intestinal Epithelial Integrity and Gastrointestinal Symptoms

Figure 2

—Blood markers of gastrointestinal injury pre-, post-, and 1 hr postexercise trials in CON, LCHF, and LEA groups across the Baseline (light) and Adaptation (dark) trials. Absolute concentrations of I-FABP (A) LBP (C), and sCD14 (E) have been presented (mean ± SD), alongside delta change scores for pre- to postexercise (B, D, and F; data presented as 25th–75th percentile + min/max). *A significant Diet × Trial interaction effect. #The post hoc analysis, where differences compared to Baseline are evident. ^The post hoc analysis, where differences compared to LCHF are evident. CON = high carbohydrate/high energy control diet; LCHF = low-carbohydrate, high-fat diet; LEA = low energy availability diet; I-FABP = intestinal fatty acid-binding protein; LBP = lipopolysaccharide-binding protein; sCD14 = soluble CD14.

Citation: International Journal of Sport Nutrition and Exercise Metabolism 33, 6; 10.1123/ijsnem.2023-0009

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