*Edinger Institute, Institute of Neurology, University of Frankfurt am Main

‡‡‡Frankfurt Cancer Institute (FCI), Frankfurt am Main

Departments of †Neuropathology

#Neurosurgery

***Radiation Oncology and Radiotherapy, Charité—Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin

¶¶Cluster of Excellence, NeuroCure

##German Center for Neurodegenerative Diseases (DZNE)

¶Schlosspark-Klinik Charlottenburg, Abteilung für Neurochirurgie

**Department of Neurosurgery, Schlosspark-Klinik Charlottenburg, Berlin

‡Department of Neurosurgery, University Hospital Münster

§§Institute of Neuropathology, University Hospital Münster, Münster

§Institute of Neuropathology, University Hospital Leipzig, Leipzig

∥Department of Neurosurgery, Klinikum Chemnitz, Chemnitz

‡‡Department of Neuropathology, University Hospital Heidelberg

∥∥German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ)

†††German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, German Cancer Research Center (DKFZ), Heidelberg, Germany

††Queen Square Brain Bank, UCL Queen Square Institute of Neurology, University College London, London, UK

C.T. and L.S. shared senior authorship.

Conception and design: C.T. and L.S. Acquisition of data: A.M., D.T., D.S., P.K., E.P., S.-A.M., W.C.M., T.K., S.N.-D., J.O., P.V., G.N., A.v.D., W.P., F.L.H., A.K., C.B., D.C., D.K., C.T., and L.S. Analysis and interpretation: A.M., D.T., C.T., and L.S. Drafting and revision of the manuscript: A.M., D.C., C.T., and L.S.

Conflicts of Interest and Source of Funding: Supported by a Deutsches Konsortium für Translationale Krebsforschung (DKTK) Young Investigator grant to L.S. The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article.

Correspondence: Leonille Schweizer, MD, Johann Wolfgang Goethe University Medical School, Institute of Neurology (Edinger Institute), Heinrich-Hoffmann Strasse 7, 60528 Frankfurt am Main, Germany (e-mail: [email protected]).

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