Caffrey MF, James DC. Human lymphocyte antigen association in ankylosing spondylitis. Nature. 1973;242(5393):121. https://doi.org/10.1038/242121a0.
Article CAS PubMed Google Scholar
Brewerton DA, Hart FD, Nicholls A, Caffrey M, James DC, Sturrock RD. Ankylosing spondylitis and HL-A 27. Lancet. 1973;1(7809):904–7. https://doi.org/10.1016/s0140-6736(73)91360-3.
Article CAS PubMed Google Scholar
Schlosstein L, Terasaki PI, Bluestone R, Pearson CM. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med. 1973;288(14):704–6. https://doi.org/10.1056/NEJM197304052881403.
Article CAS PubMed Google Scholar
Rudwaleit M, Khan MA, Sieper J. The challenge of diagnosis and classification in early ankylosing spondylitis: do we need new criteria? Arthritis Rheum. 2005;52(4):1000–8. https://doi.org/10.1002/art.20990.
Akkoc N, Khan MA. Radiographic axial spondyloarthritis versus ankylosing spondylitis. Clin Exp Rheumatol. 2016;34(1 Suppl 95):S7.
Khan MA, van der Linden S. Axial spondyloarthritis: a better name for an old disease: a step toward uniform reporting. ACR Open Rheumatol. 2019;1(5):336–9. https://doi.org/10.1002/acr2.11044.
Article PubMed PubMed Central Google Scholar
Robinson PC, van der Linden S, Khan MA, et al. Axial spondyloarthritis: concept, construct, classification, and implications for therapy. Nat Rev Rheumatol. 2021;17:109–18. https://doi.org/10.1038/s41584-020-00552-4.
Thorsby E. HL-A antigens and genes. I. A study of unrelated Norwegians. Vox Sang. 1969;17(2):81–92. https://doi.org/10.1111/j.1423-0410.1969.tb00377.x.
Article CAS PubMed Google Scholar
Allen E, Amos DB, Batchelor R. Joint report of 4th International Histocompatibility Workshop. In: Terasaki PI, editor. Histocompatibility Testing Copenhagen 1970;17–47.: Munksgaard; 1970.
Robinson J, Barker DJ, Georgiou X, Cooper MA, Flicek P, Marsh SGE. IPD-IMGT/HLA database. Nucleic Acids Res. 2020;48(D1):D948–55. https://doi.org/10.1093/nar/gkz950.
Article CAS PubMed Google Scholar
Brewerton DA. Discovery: HLA and disease. Curr Opin Rheumatol. 2003;15(4):369–73. https://doi.org/10.1097/00002281-200307000-00001.
James DC. HLA-B27 in clinical medicine–historical reflections on the discovery of the disease association. Br J Rheumatol. 1983;22(4 Suppl 2):20–4. https://doi.org/10.1093/rheumatology/xxii.suppl_2.20.
Article CAS PubMed Google Scholar
Sturrock RD. Human leukocyte antigen B27. Clin Med (Lond). 2010;10(2):162–3. https://doi.org/10.7861/clinmedicine.10-2-162.
Spencer DG, Sturrock RD, Buchanan WW. Ankylosing spondylitis: yesterday and today. Med Hist. 1980;24(1):60–9. https://doi.org/10.1017/s0025727300039788.
Article CAS PubMed PubMed Central Google Scholar
Stecher RM, Hauser H. Ankylosing spondylitis; report of occurrence in 2 brothers. Am J Roentgenol Radium Ther. 1946;56(5):601–6.
Stecher RM, Hersh AH. Familial occurrence of ankylosing spondylitis. Br J Phys Med. 1955;18(8):176–83.
Brewerton DA, Caffrey M, Nicholls A, Walters D, James DC. Acute anterior uveitis and HL-A 27. Lancet. 1973;302(7836):994–6. https://doi.org/10.1016/s0140-6736(73)91090-8.
Article CAS PubMed Google Scholar
Brewerton DA, Caffrey M, Nicholls A, Walters D, Oates JK, James DC. Reiter’s disease and HL-A 27. Lancet. 1973;302(7836):996–8. https://doi.org/10.1016/s0140-6736(73)91091-x.
Article CAS PubMed Google Scholar
Khan MA. HLA-B27 and its pathogenic role. J Clin Rheumatol. 2008;14(1):50–2. https://doi.org/10.1097/RHU.0b013e3181637a38.
Khan MA, Kushner I, Braun WE. Comparison of clinical features in HLA-B27 positive and negative patients with ankylosing spondylitis. Arthritis Rheum. 1977;20(4):909–12. https://doi.org/10.1002/art.1780200401.
Article CAS PubMed Google Scholar
Khan MA, Braun WE, Kushner I, Grecek DE, Muir WA, Steinberg AG. HLA B27 in ankylosing spondylitis: differences in frequency and relative risk in American Blacks and Caucasians. J Rheumatol Suppl. 1977;3:39–43.
Khan MA, Kushner I, Braun WE. Genetic heterogeneity in primary ankylosing spondylitis. J Rheumatol. 1980;7(3):383–6.
Feldtkeller E, Khan A, van der Heijde D, van der Linden S, Braun J. Age at disease onset and diagnosis delay in HLA-B27 negative vs. positive patients with ankylosing spondylitis. Rheumatol Int. 2003;23(2):61–6. https://doi.org/10.1007/s00296-002-0237-4.
Akkoc N, Yarkan H, Kenar G, Khan MA. Ankylosing spondylitis: HLA-B*27-positive versus HLA-B*27-negative disease. Curr Rheumatol Rep. 2017;19(5):26. https://doi.org/10.1007/s11926-017-0654-8.
Article CAS PubMed Google Scholar
Cui Z, Hou G, Meng X, Feng H, He B, Tian Y. Bidirectional causal associations between inflammatory bowel disease and ankylosing spondylitis: a two-sample Mendelian randomization analysis. Front Genet. 2020;19(11):587876. https://doi.org/10.3389/fgene.2020.587876.
Arévalo M, Gratacós Masmitjà J, Moreno M, Calvet J, Orellana C, Ruiz D, et al; REGISPONSER group. Influence of HLA-B27 on the ankylosing spondylitis phenotype: results from the REGISPONSER database. Arthritis Res Ther. 2018;20(1):221. https://doi.org/10.1186/s13075-018-1724-7. Erratum in: Arthritis Res Ther. 2020 Jun 11;22(1):140.
• Li Z, van der Linden SM, Khan MA, Baumberger H, Zandwijk HV, Khan MK, Villiger PM, Brown MA. Heterogeneity of axial spondyloarthritis: genetics, sex, and structural damage matter. RMD Open. 2022;8(1):e002302. https://doi.org/10.1136/rmdopen-2022-002302. (This study provides evidence for a high degree of heterogeneity of primary AS and recommends that stratified or adjusted analysis of effectiveness studies be performed, taking genetics, sex, and radiographic damage (sacroiliitis) into account.)
Article PubMed PubMed Central Google Scholar
Brown MA, Xu H, Li Z. Genetics and the axial spondyloarthritis spectrum. Rheumatology (Oxford). 2020;59(Suppl4):iv58–66. https://doi.org/10.1093/rheumatology/keaa464.
Zhang S, Peng L, Li Q, Zhao J, Xu D, Zhao J, et al. Spectrum of spondyloarthritis among Chinese populations. Curr Rheumatol Rep. 2022;24(8):247–58. https://doi.org/10.1007/s11926-022-01079-1.
Article CAS PubMed PubMed Central Google Scholar
Fröhlich F, Micheroli R, Hebeisen M, Kissling S, Bürki K, Exer P, et al. HLA-B27 as a predictor of effectiveness of treatment with TNF inhibitors in axial spondyloarthritis: data from the Swiss Clinical Quality Management Registry. Clin Rheumatol. 2023;42(5):1267–74. https://doi.org/10.1007/s10067-022-06490-8.
Stovall R, van der Horst-Bruinsma IE, Liu SH, Rusman T, Gensler LS. Sexual dimorphism in the prevalence, manifestation and outcomes of axial spondyloarthritis. Nat Rev Rheumatol. 2022;18(11):657–69. https://doi.org/10.1038/s41584-022-00833-0.
Khan MA, van der Linden SM, Kushner I, Valkenburg HA, Cats A. Spondylitic disease without radiologic evidence of sacroiliitis in relatives of HLA-B27 positive ankylosing spondylitis patients. Arthritis Rheum. 1985;28(1):40–3. https://doi.org/10.1002/art.1780280107.
Article CAS PubMed Google Scholar
Khan MA, van der Linden SM. A wider spectrum of spondyloarthropathies. Semin Arthritis Rheum. 1990;20(2):107–13. https://doi.org/10.1016/0049-0172(90)90023-9.
Article CAS PubMed Google Scholar
Malaviya AN, Kalyani A, Rawat R, Gogia SB. Comparison of patients with ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA) from a single rheumatology clinic in New Delhi. Int J Rheum Dis. 2015;18(7):736–41. https://doi.org/10.1111/1756-185X.12579.
Bittar M, Yong WC, Magrey M, Khan MA. Worldwide differences in clinical phenotype of axial spondyloarthritis. Curr Rheumatol Rep. 2021;23(10):76. https://doi.org/10.1007/s11926-021-01043-5.
Burgos-Varga R, Wei JC, Rahman MU, Akkoc N, Haq SA, Hammoudeh M, et al. The prevalence and clinical characteristics of nonradiographic axial spondyloarthritis among patients with inflammatory back pain in rheumatology practices: a multinational, multicenter study. Arthritis Res Ther. 2016;18(1):132. https://doi.org/10.1186/s13075-016-1027-9.
Article CAS PubMed PubMed Central Google Scholar
Haroon NN, Paterson JM, Li P, Haroon N. Increasing proportion of female patients with ankylosing spondylitis: a population-based study of trends in the incidence and prevalence of AS. BMJ Open. 2014;4(12):e006634. https://doi.org/10.1136/bmjopen-2014-006634.
Comments (0)