Kirkpatrick B, Fenton WS, Carpenter WT Jr, Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull. 2006;32:214–9. https://doi.org/10.1093/schbul/sbj053.

Article  PubMed  PubMed Central  Google Scholar 

Galderisi S, Mucci A, Buchanan RW, Arango C. Negative symptoms of schizophrenia: new developments and unanswered research questions. Lancet Psychiatry. 2018;5:664–77. https://doi.org/10.1016/S2215-0366(18)30050-6.

Article  PubMed  Google Scholar 

Marder SR, Galderisi S. The current conceptualization of negative symptoms in schizophrenia. World Psychiatry. 2017;16:14–24. https://doi.org/10.1002/wps.20385.

Article  PubMed  PubMed Central  Google Scholar 

Upthegrove R, Marwaha S, Birchwood M. Depression and Schizophrenia: Cause, Consequence, or Trans-diagnostic Issue? Schizophr Bull. 2017;43:240–4. https://doi.org/10.1093/schbul/sbw097.

Article  PubMed  Google Scholar 

Demyttenaere K, Anthonis E, Acsai K, Correll CU. Depressive symptoms and panss symptom dimensions in patients with predominant negative symptom schizophrenia: a network analysis. Front Psychiatry. 2022;13: 795866. https://doi.org/10.3389/fpsyt.2022.795866.

Article  PubMed  PubMed Central  Google Scholar 

Ahangari M, Bustamante D, Kirkpatrick R, Nguyen TH, Verrelli BC, Fanous A, et al. Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophrenia. Br J Psychiatry. 2022. https://doi.org/10.1192/bjp.2022.179.

Article  Google Scholar 

Kirschner M, Schmidt A, Hodzic-Santor B, Burrer A, Manoliu A, Zeighami Y, et al. Orbitofrontal-striatal structural alterations linked to negative symptoms at different stages of the schizophrenia spectrum. Schizophr Bull. 2021;47:849–63. https://doi.org/10.1093/schbul/sbaa169.

Article  PubMed  Google Scholar 

Galderisi S, Mucci A, Dollfus S, Nordentoft M, Falkai P, Kaiser S, et al. EPA guidance on assessment of negative symptoms in schizophrenia. Eur Psychiatry. 2021;64: e23. https://doi.org/10.1192/j.eurpsy.2021.11.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Meiseberg J, Moritz S. Biases in diagnostic terminology: clinicians choose different symptom labels depending on whether the same case is framed as depression or schizophrenia. Schizophr Res. 2020;222:444–9. https://doi.org/10.1016/j.schres.2020.03.050.

Article  PubMed  Google Scholar 

Chaturvedi SK, Sarmukaddam S. Negative symptoms in depression. Indian J Psychiatry. 1985;27:139–44.

CAS  PubMed  PubMed Central  Google Scholar 

Galynker II, Cohen LJ, Cai J. Negative symptoms in patients with major depressive disorder: a preliminary report. Neuropsychiatry Neuropsychol Behav Neurol. 2000;13:171–6.

CAS  PubMed  Google Scholar 

Bottlender R, Sato T, Groll C, Jager M, Kunze I, Moller HJ. Negative symptoms in depressed and schizophrenic patients: how do they differ? J Clin Psychiatry. 2003;64:954–8. https://doi.org/10.4088/jcp.v64n0816.

Article  PubMed  Google Scholar 

Chuang JY, Murray GK, Metastasio A, Segarra N, Tait R, Spencer J, et al. Brain structural signatures of negative symptoms in depression and schizophrenia. Front Psychiatry. 2014;5:116. https://doi.org/10.3389/fpsyt.2014.00116.

Article  PubMed  PubMed Central  Google Scholar 

Richter J, Holz L, Hesse K, Wildgruber D, Klingberg S. Measurement of negative and depressive symptoms: Discriminatory relevance of affect and expression. Eur Psychiatry. 2019;55:23–8. https://doi.org/10.1016/j.eurpsy.2018.09.008.

Article  PubMed  Google Scholar 

Krynicki CR, Upthegrove R, Deakin JFW, Barnes TRE. The relationship between negative symptoms and depression in schizophrenia: a systematic review. Acta Psychiatr Scand. 2018;137:380–90. https://doi.org/10.1111/acps.12873.

Article  CAS  PubMed  Google Scholar 

Kim YK, Park SC. An alternative approach to future diagnostic standards for major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2021;105: 110133. https://doi.org/10.1016/j.pnpbp.2020.110133.

Article  PubMed  Google Scholar 

Kring AM, Gur RE, Blanchard JJ, Horan WP, Reise SP. The Clinical Assessment Interview for Negative Symptoms (CAINS): final development and validation. Am J Psychiatry. 2013;170:165–72. https://doi.org/10.1176/appi.ajp.2012.12010109.

Article  PubMed  PubMed Central  Google Scholar 

Haguiara B, Koga G, Diniz E, Fonseca L, Higuchi CH, Kagan S, et al. What is the best latent structure of negative symptoms in schizophrenia? A systematic review. Schizophr Bull Open. 2021;2:sgab013. https://doi.org/10.1093/schizbullopen/sgab013.

Article  PubMed  PubMed Central  Google Scholar 

Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59(Suppl 20):22–33 (quiz 4-57).

PubMed  Google Scholar 

Boden R, Bengtsson J, Thornblom E, Struckmann W, Persson J. Dorsomedial prefrontal theta burst stimulation to treat anhedonia, avolition, and blunted affect in schizophrenia or depression—a randomized controlled trial. J Affect Disord. 2021;290:308–15. https://doi.org/10.1016/j.jad.2021.04.053.

Article  CAS  PubMed  Google Scholar 

Persson J, Struckmann W, Gingnell M, Fallmar D, Boden R. Intermittent theta burst stimulation over the dorsomedial prefrontal cortex modulates resting-state connectivity in depressive patients: a sham-controlled study. Behav Brain Res. 2020;394: 112834. https://doi.org/10.1016/j.bbr.2020.112834.

Article  CAS  PubMed  Google Scholar 

Llerena K, Park SG, McCarthy JM, Couture SM, Bennett ME, Blanchard JJ. The Motivation and Pleasure Scale-Self-Report (MAP-SR): reliability and validity of a self-report measure of negative symptoms. Compr Psychiatry. 2013;54:568–74. https://doi.org/10.1016/j.comppsych.2012.12.001.

Article  PubMed  PubMed Central  Google Scholar 

Shafer A, Dazzi F, Ventura J. Factor structure of the Brief Psychiatric Rating Scale - Expanded (BPRS-E) in a large hospitalized sample. J Psychiatr Res. 2017;93:79–86. https://doi.org/10.1016/j.jpsychires.2017.05.011.

Article  PubMed  Google Scholar 

Guy W. ECDEU assessment manual for psychopharmacology publication. Washington: Department of health, education and welfare; 1976.

Google Scholar 

Ahmad I, Sandberg M, Brus O, Ekman CJ, Hammar Å, Landén M, et al. Validity of diagnoses, treatment dates, and rating scales in the Swedish national quality register for electroconvulsive therapy. Nord J Psychiatry. 2022;76:96–103. https://doi.org/10.1080/08039488.2021.1939416.

Article  PubMed  Google Scholar 

Svanborg P, Asberg M. A comparison between the Beck Depression Inventory (BDI) and the self-rating version of the Montgomery Asberg Depression Rating Scale (MADRS). J Affect Disord. 2001;64:203–16. https://doi.org/10.1016/s0165-0327(00)00242-1.

Article  CAS  PubMed  Google Scholar 

Parker RD, Flint EP, Bosworth HB, Pieper CF, Steffens DC. A three-factor analytic model of the MADRS in geriatric depression. Int J Geriatr Psychiatry. 2003;18:73–7. https://doi.org/10.1002/gps.776.

Article  CAS  PubMed  Google Scholar 

Watanabe K, Fujimoto S, Marumoto T, Kitagawa T, Ishida K, Nakajima T, et al. Therapeutic potential of vortioxetine for anhedonia-like symptoms in depression: a post hoc analysis of data from a clinical trial conducted in Japan. Neuropsychiatr Dis Treat. 2022;18:363–73. https://doi.org/10.2147/NDT.S340281.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Diaz AP, Fernandes BS, Teixeira AL, Mwangi B, Hasan KM, Wu MJ, et al. White matter microstructure associated with anhedonia among individuals with bipolar disorders and high-risk for bipolar disorders. J Affect Disord. 2022;300:91–8. https://doi.org/10.1016/j.jad.2021.12.037.

Article  PubMed  Google Scholar 

Zheng W, Gu LM, Sun CH, Zhou YL, Wang CY, Lan XF, et al. Comparative effectiveness of repeated ketamine infusions in treating anhedonia in bipolar and unipolar depression. J Affect Disord. 2022;300:109–13. https://doi.org/10.1016/j.jad.2021.12.105.

Article  CAS  PubMed  Google Scholar 

Fekadu A, Wooderson S, Donaldson C, Markopoulou K, Masterson B, Poon L, et al. A multidimensional tool to quantify treatment resistance in depression: the Maudsley staging method. J Clin Psychiatry. 2009;70:177–84. https://doi.org/10.4088/jcp.08m04309.

Article  PubMed  Google Scholar 

The EuroQol Group. A new facility for the measurement of health-related quality of life. Health Policy. 1990;16:199–208.

Article  Google Scholar 

Teni FS, Burström K, Devlin N, Parkin D, Rolfson O. Experience-based health state valuation using the EQ VAS: a register-based study of the EQ-5D-3L among nine patient groups in Sweden. Health Qual Life Outcomes. 2023;21:34. https://doi.org/10.1186/s12955-023-02115-z.

Article  PubMed  PubMed Central  Google Scholar 

Burström K, Johannesson M, Diderichsen F. Health-related quality of life by disease and socio-economic group in the general population in Sweden. Health Policy. 2001;55:51–69. https://doi.org/10.1016/S0168-8510(00)00111-1.

Article  PubMed  Google Scholar 

Johansson R, Carlbring P, Heedman A, Paxling B, Andersson G. Depression, anxiety and their comorbidity in the Swedish general population: point prevalence and the effect on health-related quality of life. PeerJ. 2013;1: e98. https://doi.org/10.7717/peerj.98.

Article  PubMed  PubMed Central