A SYSTEMATIC REVIEW : CARDIOVASCULAR EFFECTS OF SYSTEMIC SCLEROSIS

Abstract

Systemic sclerosis is a connective autoimmune disorder characterized by the deposition of an extracellular matrix in the internal organs leading to fibrosis and damage to internal organs.Cardiovascular effects of systemic sclerosis include arrhythmias,coronary artery disease,valvular diseases,pericardial diseases,atherosclerosis,myocardial diseases .Thus it also has a fatal effect on the cardiovascular system making it significant to know its epidemiology, pathophysiology, screening techniques, and investigations which help in early diagnosis of the cardiac lesions of systemic sclerosis. Cardiovascular effects of systemic sclerosis is a multidisciplinary approach by a rheumatologist, cardiologist and radiologist . We reviewed 182 articles from renowned journals taken from google scholar and pubmed published between 2010 and 2023 of which 8 articles are focused for in depth review .This systematic review summarizes the effects of systemic sclerosis on cardiovascular system ranging from arrhythmias to pericardial diseases in brief including the pathogenesis , investigations and epidemiology.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

THIS STUDY DID NOT RECEIVE ANY FUNDING

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

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The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

THE STUDY USED ONLY OPENLY AVAILABLE DATA THAT ARE ORIGINALLY LOCATED IN PUB MED AND GOOGLE SCHOLAR

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I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

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Data Availability

ALL DATA PRODUCED IN THE PRESENT WORK ARE CONTAINED IN THE MANUSCRIPT

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