LETTER TO EDITOR Year : 2023  |  Volume : 71  |  Issue : 5  |  Page : 1076

COVID-19 Vaccine, Safety in a Case with Underlying Pituitary Adenoma

Amnuay Kleebayoon1, Viroj Wiwanitkit2
1 Private Academic Consultant, Samraong, Cambodia
2 Adjunct Professor, Joesph Ayobabalola University, Ikeji-Arakeji, Nigeria

Date of Submission28-May-2023Date of Decision02-Jun-2023Date of Acceptance02-Jun-2023Date of Web Publication18-Oct-2023

Correspondence Address:
Amnuay Kleebayoon
Private Academic Consultant, Samraong
Cambodia

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0028-3886.388052

How to cite this article:
Kleebayoon A, Wiwanitkit V. COVID-19 Vaccine, Safety in a Case with Underlying Pituitary Adenoma. Neurol India 2023;71:1076

Sir,

The main issue that everyone considers about vaccination is the vaccine's safety. There are several unanswered questions regarding coronavirus disease 2019 (COVID-19) vaccine, which is a novel vaccine. A 58-year-old Asian woman presented to us with pituitary adenoma and had undergone transnasal surgery for the tumor 4 months ago. She inquired as to whether getting the COVID-19 vaccine was safe for her. According to a literature search, there are no published studies examining the precise impact of the COVID-19 and influenza vaccines on the pituitary gland, though some researchers contend that inflammation of the pituitary gland, which can result in hormonal imbalances, is a rare side effect of vaccines in general.

The studies on pituitary apoplexy following COVID-19 immunization are currently available.[1],[2] There is a counterargument that the vaccine is not clearly to blame for the issue, and that it is impossible to rule out other potential factors.[3],[4] The woman decided to get vaccinated with the COVID-19 vaccine after the consultation. She has already received all the recommended doses of the vaccine and there were no issues after the vaccination. Also, the patient's follow-up hormone profile during the clinical follow-up appointment after pituitary surgery showed no abnormalities. This may be an instance showing that COVID-19 vaccination is likely to be safe for people who have an underlying pituitary tumor and it does not cause any harmful side effects for the vaccine recipient.

Authors' contribution

AK writing, analyzing, approval for submission

VW supervision

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 

  References 
1.Piñar-Gutiérrez A, Remón-Ruiz P, Soto-Moreno A. Case report: Pituitary apoplexy after COVID-19 vaccination. Med Clin (Engl Ed) 2022;158:498-9.  
    2.Zainordin NA, Hatta SFWM, Ab Mumin N, Shah FZM, Ghani RA. Pituitary apoplexy after COVID-19 vaccination: A case report. J Clin Transl Endocrinol Case Rep 2022;25:100123. doi: 10.3389/fendo. 2022.1035482.  
    3.Mungmunpuntipantip R, Wiwanitkit V. Pituitary apoplexy and COVID-19 vaccination. Med Clin (Barc) 2022;159:e11. doi: 10.1016/j.medcli.2021.12.015.  
    4.Taieb A, Asma BA, Mounira EE. Evidences that SARS-CoV-2 vaccine-induced apoplexy may not be solely due to ASIA or VITT syndrome', Commentary on pituitary apoplexy and COVID-19 vaccination: A case report and literature review. Front Endocrinol (Lausanne) 2023;14:1111581. doi: 10.3389/fendo. 2023.1111581.