A major factor in health disparities in the United States is the body's response to chronic stress. Weathering is a concept to describe how everyday exposures to social inequities stemming from structural racism and poverty produces wear and tear on the body at the cellular level, damaging telomeres, and cardiovascular, neuroendocrine, and metabolic systems. In our guest editorial, Dr. SmithBattle, describes the implications of weathering on maternal health disparities.