AbbreviationAAK1

AP2 Associated Kinase 1

AOAH

Acyloxyacyl hydrolase

CARD

Caspase recruitment and activation domain

cGAS

Cyclic GMP-AMP synthase

CLP

Cecal ligation and puncture

COVID-19

Coronavirus Disease 2019

CPA

Chimeric peptidomimetic antibiotic

CSS

cytokine storm syndrome

DAMPs

Damage-associated molecular patterns

DIC

Disseminated intravascular coagulation

ECP

Eosinophil cationic protein

Galectin-3

β-galactoside-binding proteins 3

GBPs

Guanylate binding proteins

GPX4

Glutathione peroxidase 4

GPX8

Glutathione peroxidase 8

hCAP18

Human cationic antimicrobial polypeptide of 18-kDa

HMGB1

High mobility group box-1

HSPA12A

Heat shock protein 12A

ITPR1

Inositol 1,4,5-Trisphosphate Receptor Type 1

JNK

c-Jun N-terminal kinase

LPC

Lysophosphatidylcholine

NT-GSDMD

N-terminal domains liberated from GSDMD

OMVs

Outer membrane vesicles

oxPAPC

oxidized phospholipid 1-palmitoyl-2-arachidonoyl-sn-glycerol-3-phosphorylcholine

PAMP

Pathogen-associated molecular patterns

Pep19–2.5

Synthetic LPS-binding peptide 19–2.5

PGC-1α

Proliferator-activated receptor γ coactivator 1α

PHZ-OH

7-(diethylamino)− 1-hydroxy-phenothiazin-3-ylidene-diethylazanium chloride

RAGE

Receptors for advanced glycation end-products

ROS

Reactive oxygen species

SERPINB1

Serpin family B member 1

TBK1

TANK binding kinase 1

T3SS

Type III secretion system

TMEM16F

transmembrane protein 16 F

TMEM173

transmembrane protein 173

TPNs

Tea polyphenols nanoparticles

Keywords

Noncanonical inflammasome

Pyroptosis

Sepsis

Caspase-4\5\11

Gasdermin D

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