ACROSS

1. Unexciting people, as coined by TikTok

5. Large punch bowl

10. "There is no Mystery so great ___." Wilde

18. Turow book about law school

19. About to explode

20. Tibial region

21. Small molecule disease target

23. Personal perspective

24. Wean, at times

25. Small molecule monitoring tests

27. Stomach muscles, briefly

28. "View of Toledo" artist

32. Aloof

33. "Hogwash!"

35. "___ rang?"

36. Cousin of a clog

39. Small mol. screening test target

42. Small molecule blocker target

46. Greet a Welsh lad

47. "To ___ is human ..."

48. Zilch

49. Potions

51. Small mol. blocking target

55. Small molecule complications

57. Pests in the yard

58. Sea bird

59. Normal school, briefly

60. Ambulance team, for short

61. Even if, commonly

63. Mechanics' org.

64. "Touched By an Angel" co-star

66. Tread in Toledo

68. Comes to room temperature, as butter

70. Culprit description in "The Fugitive"

72. Actress Tyler

74. Drone, e.g.

75. ___ liquor

76. Small molecule disease target

82. Cousin of -trix

83. Mound

84. IRS time

85. Ponzi scheme, e.g.

86. 52, in old Rome

87. Formel offspring

91. Mendes or Longoria

92. Small molecule mechanisms, with 100 across

97. Toys with tails

99. Wheelchair bound TV detective

100. See 92 across

104. Drove nuts

105. Caribbean cruise stop

106. "Green Gables" girl

107. Charges

108. Destitute

109. Detective's need

DOWN

1. Most "Bewitched" characters

2. Live

3. Diving sometimes

4. Veer

5. Small mol. disease target

6. Crumb

7. 1990's Indian P.M.

8. Handy

9. "M*A*S*H" extra

10. World-wide Korean grocer

11. Tool site, often

12. Tons

13. Expose to illness

14. Smart

15. Ashtabula's lake

16. Casting need

17. Swerves at sea

22. G.I. chow in WWII

26. Announce

29. Elastane fabrics

30. Caught

31. Spoil

34. Jean and Catherine

37. "___ it the truth!"

38. Lifts up

39. Pudding-like dessert

40. Eardrum combining form

41. Heads

43. More chichi

44. Lying and cheating

45. Certain boarding schools

46. Swimsuit part

50. Double

51. Broadway composer Kern

52. Bowls

53. Gets down

54. Mississippi city where Elvis was born

56. "Hamlet" courtier

62. Tasmanian capital

65. Hung around

67. "American ___"

69. Caddie's bagful

71. Full body simulators for training

73. Container for nitroglycerin

77. "Guilty," e.g.

78. "Tarzan" extra

79. Common solvent

80. Greek cafe

81. Collected together

83. Some chocolates

86. Norwegian puffin

88. Pear

89. Romance, e.g.

90. Schuss, e.g.

92. Iwo ___

93. Long Caucasus river that flows to the Kura River

94. Acceptances

95. ___ fixe

96. Beatty and Eisenberg

98. Emphatic type: Abbr.

101. Cast

102. Small mol. disease target

103. Aircraft compartment