Does it matter that standard preparedness indices did not predict COVID-19 outcomes?

But do the analyses comparing mortality to SPAR and JEE scores and the GHSI really prove that these measures are not valid measures of a country’s preparedness [9, 10]? Predictive validity, the degree to which a measure statistically predicts desirable outcomes, is a common way to assess performance measures. For example, measures of a hospital’s adherence to infection control protocols should be associated with lower surgical mortality rates. Nevertheless, there are several reasons that these instruments should not be so easily rejected as preparedness measures.

First, as Stoto and colleagues [11] note, the comparability of such data (which come from the Johns Hopkins University COVID-19 Dashboard, Worldometer, and similar sources) over time and among jurisdictions is questionable due to highly variable completeness and representativeness [12, 13]. Indeed, countries that have stronger public health systems—and thus higher scores for surveillance in particular and preparedness overall— may be more likely to count COVID-19 cases and deaths completely. This would create a correlation in the wrong direction.

Second, these studies use relatively simple outcome measures, mostly based on cumulative numbers of cases and deaths at the country level and at a fixed point of time. However, a country’s “success” in dealing with the pandemic is highly multidimensional – both in the health outcomes and type and timing of interventions and policies. Performance as measure by cumulative numbers of cases or deaths early in the pandemic might be contradicted by performance in later stages (e.g. when the vaccine became available). Total cases and deaths also do not reflect differences within countries by socio-economic groups, geography, or other factors. In addition, limiting social and economic disruption is an important policy aim that is not addressed by case/death counts. In other words, the impact of capabilities that were highly effective for some groups at a specific time might not be observed in cumulative mortality figures.

Third, the analyses to assess predictive validity use cross-sectional designs with outcome data aggregated over multiple epidemic phases, which is poorly suited for evaluating the impact of interventions, especially for COVID-19 policies, where part of the challenge was to adjust policies to the emergence of new variables and new socio-economic impacts over the long course of the pandemic [11, 14]. Cross-sectional studies are even more problematical where, as in the case of COVID-19, both outcomes and interventions are highly multidimensional, as discussed in the previous paragraph.

Beyond questions of data quality and study design, there is a serious conceptual issue: a major reason that current preparedness measures fail to predict pandemic outcomes is that they do not adequately capture variations in the presence of effective political leadership needed to activate and implement existing system, instill confidence in the government’s response; or background levels of interpersonal trust and trust in government institutions and country ability needed to mount fast and adaptable responses. As Bell, Fukayama, and others have noted, these factors are crucial; capacity alone is insufficient if that capacity isn’t effectively leveraged [15, 16]. These factors might be labeled “social capital, and represent the difference between preparedness and resilience [17].

Ledesma and colleagues [18] recently analyzed the relationship between GHSI scores and COVID-19 outcomes and found a quite different result than the others cited in this section: higher GHSI scores were associated with lower COVID-19 deaths18. Part of the reason for the difference is that these authors avoided problems of undercounting by focusing on excess mortality estimates. They also adjusted for population age and looked at mortality over two years (2020 and 2021) rather than a limited window. Ledesma and colleagues further analyzed the results in a multivariate regression exploring the impact of the six components of the GHSI. Controlling for the other components, they found that the “risk environment score” had a stronger relationship to COVID-19 mortality than any of the others. This score includes government effectiveness, public confidence in governance, trust in medical and health advice, and related factors. Thus, it differs conceptually from the other five components, which are more traditional preprepared measures. This suggests that the GHSI is a good measure of resilience, measuring both preparedness and social capital.

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