Morley JE, Vellas B, van Kan GA, Anker SD, Bauer JM, Bernabei R, et al. Frailty consensus: a call to action. J Am Med Dir Assoc. 2013;14:392–7.

Article  PubMed  PubMed Central  Google Scholar 

Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146–56.

Article  CAS  PubMed  Google Scholar 

Ensrud KE, Ewing SK, Cawthon PM, Fink HA, Taylor BC, Cauley JA, et al. A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men. J Am Geriatr Soc. 2009;57:492–8.

Article  PubMed  PubMed Central  Google Scholar 

Mitnitski AB, Song X, Rockwood K. The estimation of relative fitness and frailty in community-dwelling older adults using self-report data. J Gerontol A Biol Sci Med Sci. 2004;59:M627–32.

Article  PubMed  Google Scholar 

Church S, Rogers E, Rockwood K, Theou O. A scoping review of the clinical frailty scale. BMC Geriatr. 2020;20:393.

Article  PubMed  PubMed Central  Google Scholar 

Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc. 2012;60:1487–92.

Article  PubMed  Google Scholar 

Wu W, Hu SC. Prevalence of frailty in Taiwanese elderly: A comparison of Taiwan urban and rural areas. Innov Aging. 2017;1:385.

Article  PubMed Central  Google Scholar 

Chen CY, Wu SC, Chen LJ, Lue BH. The prevalence of subjective frailty and factors associated with frailty in Taiwan. Arch Gerontol Geriatr. 2010;50(Suppl 1):S43–7.

Article  PubMed  Google Scholar 

Chen LJ, Chen CY, Lue BH, Tseng MY, Wu SC. Prevalence and associated factors of frailty among elderly people in Taiwan. Int J Gerontol. 2014;8:114–9.

Article  Google Scholar 

Vermeiren S, Vella-Azzopardi R, Beckwée D, Habbig AK, Scafoglieri A, Jansen B, et al. Frailty and the prediction of negative health outcomes: a meta-analysis. J Am Med Dir Assoc. 2016;17:1163.e1–e17.

Article  PubMed  Google Scholar 

Chi J, Chen F, Zhang J, Niu X, Tao H, Ruan H, et al. Impacts of frailty on health care costs among community-dwelling older adults: A meta-analysis of cohort studies. Arch Gerontol Geriatr. 2021;94:104344.

Article  PubMed  Google Scholar 

de Rezende LF, Rodrigues Lopes M, Rey-López JP, Matsudo VK, Luiz OC. Sedentary behavior and health outcomes: an overview of systematic reviews. PLoS One. 2014;9:e105620.

Article  PubMed  PubMed Central  Google Scholar 

Pate RR, O’Neill JR, Lobelo F. The evolving definition of “sedentary.” Exerc Sport Sci Rev. 2008;36:173–8.

Article  PubMed  Google Scholar 

Atkin AJ, Gorely T, Clemes SA, Yates T, Edwardson C, Brage S, et al. Methods of measurement in epidemiology: sedentary behaviour. Int J Epidemiol. 2012;41:1460–71.

Article  PubMed  PubMed Central  Google Scholar 

Harvey JA, Chastin SF, Skelton DA. How sedentary are older people? a systematic review of the amount of sedentary behavior. J Aging Phys Act. 2015;23:471–87.

Article  PubMed  Google Scholar 

Hsueh MC, Liao Y, Chang SH. Are total and domain-specific sedentary time associated with overweight in older Taiwanese adults. Int J Environ Res Public Health. 2015;12:12697–705.

Article  PubMed  PubMed Central  Google Scholar 

Chang SH, Rutherford R, Hsueh MC, Yu YC, Park JH, Wang S, et al. Neighborhood environment and objectively measured sedentary behavior among older adults: a cross-sectional study. Front Public Health. 2020;8:552198.

Article  PubMed  Google Scholar 

Kehler DS, Hay JL, Stammers AN, Hamm NC, Kimber DE, Schultz ASH, et al. A systematic review of the association between sedentary behaviors with frailty. Exp Gerontol. 2018;114:1–12.

Article  PubMed  Google Scholar 

Tolley APL, Ramsey KA, Rojer AGM, Reijnierse EM, Maier AB. Objectively measured physical activity is associated with frailty in community-dwelling older adults: a systematic review. J Clin Epidemiol. 2021;137:218–30.

Article  PubMed  Google Scholar 

Blodgett J, Theou O, Kirkland S, Andreou P, Rockwood K. The association between sedentary behaviour, moderate-vigorous physical activity and frailty in NHANES cohorts. Maturitas. 2015;80:187–91.

Article  PubMed  Google Scholar 

Nagai K, Tamaki K, Kusunoki H, Wada Y, Tsuji S, Ito M, et al. Isotemporal substitution of sedentary time with physical activity and its associations with frailty status. Clin Interv Aging. 2018;13:1831–6.

Article  PubMed  PubMed Central  Google Scholar 

Mañas A, Pozo-Cruz BD, Rodríguez-Gómez I, Losa-Reyna J, Rodríguez-Mañas L, García-García FJ, et al. Can physical activity offset the detrimental consequences of sedentary time on frailty? a moderation analysis in 749 older adults measured with accelerometers. J Am Med Dir Assoc. 2019;20:634–8.e1.

Article  PubMed  Google Scholar 

Higueras-Fresnillo S, de la Cámara M, Cabanas-Sánchez V, Martínez-Gómez D. Associations of Frailty and Physical Function with a Daily Activities Measured by a Pattern-Recognition Activity Monitor: An Isotemporal Substitution Analysis in the IMPACT65+ Study. J Nutr Health Aging. 2020;24:55–62.

Article  CAS  PubMed  Google Scholar 

Razjouyan J, Naik AD, Horstman MJ, Kunik ME, Amirmazaheri M, Zhou H, et al. Wearable sensors and the assessment of frailty among vulnerable older adults: an observational cohort study. Sensors (Basel). 2018;18:1336.

Article  PubMed  Google Scholar 

da Silva Coqueiro R, de Queiroz BM, Oliveira DS, das Merces MC, Oliveira Carneiro JA, Pereira R, et al. Cross-sectional relationships between sedentary behavior and frailty in older adults. J Sports Med Phys Fitness. 2017;57:825–30.

Article  PubMed  Google Scholar 

Del Pozo-Cruz B, Mañas A, Martín-García M, Marín-Puyalto J, García-García FJ, Rodriguez-Mañas L, et al. Frailty is associated with objectively assessed sedentary behaviour patterns in older adults: Evidence from the Toledo Study for Healthy Aging (TSHA). PLoS One. 2017;12:e0183911.

Article  PubMed  PubMed Central  Google Scholar 

Chen S, Chen T, Kishimoto H, Yatsugi H, Kumagai S. Associations of objectively measured patterns of sedentary behavior and physical activity with frailty status screened by the frail scale in Japanese community-dwelling older adults. J Sports Sci Med. 2020;19:166–74.

PubMed  PubMed Central  Google Scholar 

Castaneda-Gameros D, Redwood S, Thompson JL. Physical activity, sedentary time, and frailty in older migrant women from ethnically diverse backgrounds: a mixed-methods study. J Aging Phys Act. 2018;26:194–203.

Article  PubMed  Google Scholar 

Kehler DS, Clara I, Hiebert B, Stammers AN, Hay JL, Schultz A, et al. The association between bouts of moderate to vigorous physical activity and patterns of sedentary behavior with frailty. Exp Gerontol. 2018;104:28–34.

Article  PubMed  Google Scholar 

Tsai JS, Wu CH, Chen SC, Huang KC, Chen CY, Chang CI, et al. Plasma adiponectin levels correlate positively with an increasing number of components of frailty in male elders. PLoS One. 2013;8:e56250.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Orme JG, Reis J, Herz EJ. Factorial and discriminant validity of the Center for Epidemiological Studies Depression (CES-D) scale. J Clin Psychol. 1986;42:28–33.

Article  CAS  PubMed  Google Scholar 

Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc. 2020;21:300–7.e2.

Article  PubMed  Google Scholar 

Topolski TD, LoGerfo J, Patrick DL, Williams B, Walwick J, Patrick MB. The Rapid Assessment of Physical Activity (RAPA) among older adults. Prev Chronic Dis. 2006;3:A118.

PubMed  PubMed Central  Google Scholar 

Chou YC, Tsou HH, Chan DD, Wen CJ, Lu FP, Lin KP, et al. Validation of clinical frailty scale in Chinese translation. BMC Geriatr. 2022;22:604.

Article  PubMed  PubMed Central  Google Scholar 

Li HY, Mao HF, Chen YM, Chen CY. Comparison of four frailty Indices with multiple aging functional risks in healthy elderly (content in Chinese). Formos J Med. 2020;24:371–82.

Google Scholar 

Heesch KC, Hill RL, Aguilar-Farias N, van Uffelen JGZ, Pavey T. Validity of objective methods for measuring sedentary behaviour in older adults: a systematic review. Int J Behav Nutr Phys Act. 2018;15:119.

Article  PubMed  PubMed Central  Google Scholar 

Honda T, Chen S, Yonemoto K, Kishimoto H, Chen T, Narazaki K, et al. Sedentary bout durations and metabolic syndrome among working adults: a prospective cohort study. BMC Public Health. 2016;16:888.

Article  PubMed  PubMed Central  Google Scholar 

Li T, Pan Y, He Q, Du L, Chen K, Ren X, et al. Associations between sedentary behaviour, physical activity and frailty in older Chinese women: a cross-sectional study. J Clin Nurs. 2023;32:825–33.

Article  PubMed  Google Scholar 

Park KN, Kim SH. Consumer wearable device-based measures of physical activity and energy expenditure in community-dwelling older adults with different levels of frailty: a STROBE compliant study. Medicine (Baltimore). 2022;101:e31863.

Article