Advances in Pharmacology and Pharmacy Vol. 11(4), pp. 239 - 244
DOI: 10.13189/app.2023.110401
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Albashir Tahir 1,*, Hauwau Abubakar 1, Aminu Umar Kura 1, Suleiman Yunusa 1, Yahaya M Katagum 2
1 Department of Pharmacology, Faculty of Basic Medical Sciences, Bauchi State University Gadau, Nigeria
2 Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Bauchi State University Gadau, Nigeria

ABSTRACT

The use of plants in traditional medicine entails the use of many substances in the cure of both chronic diseases as well as some acute infectious diseases. Herbal medicine is one of the oldest forms of healthcare known to mankind and has been an integral part of healthcare for many centuries, with many people depending on it as their primary form of treatment. Boswellia dalzielii is a plant belonging to the family Burseraceae, which has been widely used in African traditional medicine and was locally reported to have a wide array of medicinal values in folk medicine. The aim of this study is to assess the anticonvulsant potential of the methanolic stem bark extract of Boswellia dalzielii in mice. Phytochemical screening, acute toxicity studies were carried out. The result of the phytochemical screening of the methanol stem bark extract indicated the presence of alkaloids, glycosides, steroids, flavonoids and saponins, and the oral acute toxicity dose was found to be greater than 2000 mg/kg. The extract was tested for anticonvulsant activity against pentylenetetrazole, and strychnine-induced seizures at 100, 200, and 300 mg/kg doses in Swiss albino mice. The extract was observed to significantly (p

KEYWORDS
Anticonvulsant, Boswellia dalzielii, Boswellia dalzielii Methanol Extract, Epilepsy, Pentylenetetrazole, Strychnine

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Albashir Tahir , Hauwau Abubakar , Aminu Umar Kura , Suleiman Yunusa , Yahaya M Katagum , "The Anticonvulsant Potential of Boswellia dalzielii in Mice – Pilot Study," Advances in Pharmacology and Pharmacy, Vol. 11, No. 4, pp. 239 - 244, 2023. DOI: 10.13189/app.2023.110401.

(b). APA Format:
Albashir Tahir , Hauwau Abubakar , Aminu Umar Kura , Suleiman Yunusa , Yahaya M Katagum (2023). The Anticonvulsant Potential of Boswellia dalzielii in Mice – Pilot Study. Advances in Pharmacology and Pharmacy, 11(4), 239 - 244. DOI: 10.13189/app.2023.110401.