Diagnostic and prognostic values of abdominal ultrasound combined with urinary intestinal fatty acid binding protein for neonatal necrotizing enterocolitis

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metadata.dc.identifier.doi: https://doi.org/10.56042/ijeb.v61i07.2467Title: Diagnostic and prognostic values of abdominal ultrasound combined with urinary intestinal fatty acid binding protein for neonatal necrotizing enterocolitisAuthors: Tu, Xiaoqiong
Jia, DezhaoKeywords: Neonates;Receiver operating characteristic (ROC) curvesIssue Date: Jun-2023Publisher: NIScPR-CSIR, IndiaAbstract: Necrotizing enterocolitis (NEC) triggers extensive or localized necrosis of the small intestine and colon in neonates. Here, we studied the diagnostic and prognostic values of abdominal ultrasound combined with urinary intestinal fatty acid binding protein (I-FABP) for NEC. Ninety-eight NEC neonates were divided into a suspected NEC group (n=57) and a confirmed NEC group (n=41). They were further divided into an internal medicine treatment group (n=54) and an operation group (n=44) according to disease progression. The influencing factors were explored by multivariate analysis. The diagnostic values of abdominal ultrasound and I-FABP alone or in combination were analyzed by receiver operating characteristic (ROC) curves. Further, 1-year survival rates were analyzed by Kaplan-Meier survival curves. Premature birth, meconium-stained amniotic fluid, neonatal septicemia, maternal gestational diabetes mellitus, non-exclusive breastfeeding, non-prophylactic application of probiotics and I-FABP >6.25 ng/mL were risk factors for NEC (P Page(s): 493-498ISSN: 0975-1009 (Online); 0019-5189 (Print)Appears in Collections:IJEB Vol.61(07) [July 2023]

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