Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/62218

metadata.dc.identifier.doi: https://doi.org/10.56042/ijeb.v61i07.2214Title: Serum triacylglycerol: A putative early biomarker of disease severity of Type 2 diabetes mellitus compared to microalbuminuriaAuthors: Sarma, Nibedita
Dawn, Somali
Dhar, Aninda
Chatterjee, Namrata
Hadem, Ibanylla Kyanjai Hynniewta
Asmita Hazra, Asmita
Pal, Amit
Sahoo, Sibasish
Dutta, Atanu Kumar
Goswami, Kalyan
SahaKeywords: Diabetic nephropathy;Glycaemia, HbA1c;Hyperglycemia;Hypertriglyceridemia;Post prandial plasma glucose;Receiver operating characteristic curveIssue Date: Jun-2023Publisher: NIScPR-CSIR, IndiaAbstract: Poorly controlled type 2 diabetes mellitus progresses to several complications including nephropathy. While glycated hemoglobin demarcates severity, urinary microalbumin indicates renal involvement. Considering nephropathy is a late manifestation of the disease, here, we explored whether serum triacylglycerol (TAG) can be used as an early disease severity biomarker. About 100 Type 2 diabetes mellitus patients were recruited and categorized as moderate (n=43) and severe (n=57) based on glycated haemoglobin (8%) level. Duration of the disease, BMI, systolic and diastolic BP, fasting and Post Prandial plasma glucose, glycated haemoglobin, serum lipid profile and urinary microalbumin were measured. Results obtained were compared between the groups and correlated. Taking glycated haemoglobin as reference, receiver operating characteristic curves were constructed for serum triacylglycerol and urinary microalbumin excretion to check their efficacy as classifier of disease severity. Significant differences (P Page(s): 499-504ISSN: 0975-1009 (Online); 0019-5189 (Print)Appears in Collections:IJEB Vol.61(07) [July 2023]

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