The Immunomodulatory Effects of Dexamethasone on Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer

Phillips RS, Friend AJ, Gibson F, et al. Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood. Cochrane Database Syst Rev. 2016. https://doi.org/10.1002/14651858.CD007786.pub3.

Article  PubMed  PubMed Central  Google Scholar 

Janinis J, Giannakakis T, Athanasiades A, et al. A randomized open-label parallel-group study comparing ondansetron with ondansetron plus dexamethasone in patients with metastatic breast cancer receiving high-dose epirubicin. A Hellenic Cooperative Oncology Group study. Tumori. 2000;86:37–41 (2000/04/25).

Article  CAS  PubMed  Google Scholar 

Brugnatelli S, Gattoni E, Grasso D, et al. Single-dose palonosetron and dexamethasone in preventing nausea and vomiting induced by moderately emetogenic chemotherapy in breast and colorectal cancer patients. Tumori. 2011;97:362–6. https://doi.org/10.1700/912.10035. (2011/07/27).

Article  CAS  PubMed  Google Scholar 

Clemons M, Simos D, Sienkiewicz M, et al. A prospective multi-centre, randomized study comparing the addition of tapering dexamethasone to other standard of care therapies for taxane-associated pain syndrome (TAPS) in breast cancer patients. Support Care Cancer. 2021;29:5787–95. https://doi.org/10.1007/s00520-021-06142-8. (2021/03/21).

Article  PubMed  Google Scholar 

Paulsen Ø, Aass N, Kaasa S, et al. Do corticosteroids provide analgesic effects in cancer patients? A systematic literature review. J Pain Symptom Manag. 2013;46:96–105. https://doi.org/10.1016/j.jpainsymman.2012.06.019. (2012/11/15).

Article  CAS  Google Scholar 

Lossignol D. A little help from steroids in oncology. J Transl Int Med. 2016;4:52–4. https://doi.org/10.1515/jtim-2016-0011. (2017/02/14).

Article  PubMed  PubMed Central  Google Scholar 

Yood MU, Wells KE, Alford SH, et al. Cardiovascular outcomes in women with advanced breast cancer exposed to chemotherapy. Pharmacoepidemiol Drug Saf. 2012;21:818–27. https://doi.org/10.1002/pds.3239. (2012/03/16).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wei L, MacDonald TM, Walker BR. Taking glucocorticoids by prescription is associated with subsequent cardiovascular disease. Ann Intern Med. 2004;141:764–70. https://doi.org/10.7326/0003-4819-141-10-200411160-00007. (2004/11/17).

Article  PubMed  Google Scholar 

Skalka HW, Prchal JT. Effect of corticosteroids on cataract formation. Arch Ophthalmol. 1980;98:1773–7. https://doi.org/10.1001/archopht.1980.01020040625007. (1980/10/01).

Article  CAS  PubMed  Google Scholar 

Messer J, Reitman D, Sacks HS, et al. Association of adrenocorticosteroid therapy and peptic-ulcer disease. N Engl J Med. 1983;309:21–4. https://doi.org/10.1056/nejm198307073090105. (1983/07/07).

Article  CAS  PubMed  Google Scholar 

Sui M, Chen F, Chen Z, et al. Glucocorticoids interfere with therapeutic efficacy of paclitaxel against human breast and ovarian xenograft tumors. Int J Cancer. 2006;119:712–7. https://doi.org/10.1002/ijc.21743. (2006/02/24).

Article  CAS  PubMed  Google Scholar 

Jain S, Dash P, Minz AP, et al. Lipopolysaccharide (LPS) enhances prostate cancer metastasis potentially through NF-κB activation and recurrent dexamethasone administration fails to suppress it in vivo. Prostate. 2019;79:168–82. https://doi.org/10.1002/pros.23722. (2018/09/29).

Article  CAS  PubMed  Google Scholar 

Zhang C, Mattern J, Haferkamp A, et al. Corticosteroid-induced chemotherapy resistance in urological cancers. Cancer Biol Ther. 2006;5:59–64. https://doi.org/10.4161/cbt.5.1.2272. (2005/11/19).

Article  CAS  PubMed  Google Scholar 

Gassler N, Zhang C, Wenger T, et al. Dexamethasone-induced cisplatin and gemcitabine resistance in lung carcinoma samples treated ex vivo. Br J Cancer. 2005;92:1084–8. https://doi.org/10.1038/sj.bjc.6602453. (2005/03/10).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang C, Beckermann B, Kallifatidis G, et al. Corticosteroids induce chemotherapy resistance in the majority of tumour cells from bone, brain, breast, cervix, melanoma and neuroblastoma. Int J Oncol. 2006;29:1295–301 (2006/10/04).

CAS  PubMed  Google Scholar 

Chen YX, Wang Y, Fu CC, et al. Dexamethasone enhances cell resistance to chemotherapy by increasing adhesion to extracellular matrix in human ovarian cancer cells. Endocr Relat Cancer. 2010;17:39–50. https://doi.org/10.1677/erc-08-0296. (2009/09/25).

Article  CAS  PubMed  Google Scholar 

Fentiman IS, Howell A, Hamed H, et al. A controlled trial of adjuvant tamoxifen, with or without prednisolone, in post-menopausal women with operable breast cancer. Br J Cancer. 1994;70:729–31. https://doi.org/10.1038/bjc.1994.384. (1994/10/01).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keith BD. Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy. BMC Cancer. 2008;8:84. https://doi.org/10.1186/1471-2407-8-84. (2008/04/01).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang C, Kolb A, Mattern J, et al. Dexamethasone desensitizes hepatocellular and colorectal tumours toward cytotoxic therapy. Cancer Lett. 2006;242:104–11. https://doi.org/10.1016/j.canlet.2005.10.037. (2005/12/13).

Article  CAS  PubMed  Google Scholar 

Skor MN, Wonder EL, Kocherginsky M, et al. Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer. Clin Cancer Res. 2013;19:6163–72. https://doi.org/10.1158/1078-0432.Ccr-12-3826. (2013/09/11).

Article  CAS  PubMed  Google Scholar 

Toulouse A, Nolan YM. A role for mitogen-activated protein kinase phosphatase 1 (MKP1) in neural cell development and survival. Neural Regen Res. 2015;10:1748–9. https://doi.org/10.4103/1673-5374.169606. (2016/01/26).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Talarico C, Dattilo V, D’Antona L, et al. SGK1, the new player in the game of resistance: chemo-radio molecular target and strategy for inhibition. Cell Physiol Biochem. 2016;39(1863–1876):20161024. https://doi.org/10.1159/000447885.

Article  CAS  Google Scholar 

Li Z, Dong J, Zou T, et al. Dexamethasone induces docetaxel and cisplatin resistance partially through up-regulating Krüppel-like factor 5 in triple-negative breast cancer. Oncotarget. 2017;8:11555–65. https://doi.org/10.18632/oncotarget.14135. (2016/12/29).

Article  PubMed  Google Scholar 

Redondo M, Téllez T, Roldan MJ, et al. Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity. Breast Cancer Res. 2007;9:R86. https://doi.org/10.1186/bcr1835. (2007/12/15).

Article  PubMed  PubMed Central  Google Scholar 

Mattern J, Büchler MW, Herr I. Cell cycle arrest by glucocorticoids may protect normal tissue and solid tumors from cancer therapy. Cancer Biol Ther. 2007;6:1345–54. https://doi.org/10.4161/cbt.6.9.4765. (2007/12/19).

Article  CAS  PubMed  Google Scholar 

Rutz HP, Mariotta M, von Knebel Doeberitz M, et al. Dexamethasone-induced radioresistance occurring independent of human papilloma virus gene expression in cervical carcinoma cells. Strahlenther Onkol. 1998;174:71–4. https://doi.org/10.1007/bf03038478. (1998/03/06).

Article  CAS  PubMed  Google Scholar 

Obradović MMS, Hamelin B, Manevski N, et al. Glucocorticoids promote breast cancer metastasis. Nature. 2019;567:540–4. https://doi.org/10.1038/s41586-019-1019-4. (2019/03/15).

Article  CAS  PubMed  Google Scholar 

Karvonen H, Arjama M, Kaleva L, et al. Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness. Cell Death Dis. 2020;11:790. https://doi.org/10.1038/s41419-020-03009-4. (2020/09/30).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Greenstein AE, Hunt HJ. Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells. Oncotarget. 2021;12:1243–55. https://doi.org/10.18632/oncotarget.27989. (2021/07/02).

Article  PubMed  PubMed Central  Google Scholar 

Aston WJ, Hope DE, Cook AM, et al. Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment. Oncoimmunology. 2019;8:e1641390. https://doi.org/10.1080/2162402x.2019.1641390. (2019/10/28).

Article  CAS  PubMed  PubMed Central  Google Scholar 

O’Loughlin M, Andreu X, Bianchi S, Chemielik E, Cordoba A, Cserni G, Figueiredo P, Floris G, Foschini MP, Heikkilä P, Kulka J, Liepniece-Karele I, Regitnig P, Reiner A, Ryska A, Sapino A, Shalaby A, Stovgaard ES, Quinn C, Walsh EM, Zolota V, Glynn SA, Callagy G. Reproducibility and predictive value of scoring stromal tumour infiltrating lymphocytes in triple-negative breast cancer: a multi-institutional study. Breast Cancer Res Treat. 2018;171(1):1–9. https://doi.org/10.1007/s10549-018-4825-8. (Epub 2018 May 17 PMID: 29774470).

Article  PubMed  Google Scholar 

Loi S, et al. Tumour-infiltrating lymphocytes and prognosis: a pooled individual patient analysis of early-stage triple-negative breast cancers. J Clin Oncol. 2019;37:559–69.

Article  PubMed  PubMed Central  Google Scholar 

Denkert C, von Minckwitz G, Darb-Esfahani S, Lederer B, Heppner BI, Weber KE, Budczies J, Huober J, Klauschen F, Furlanetto J, Schmitt WD, Blohmer JU, Karn T, Pfitzner BM, Kümmel S, Engels K, Schneeweiss A, Hartmann A, Noske A, Fasching PA, Jackisch C, van Mackelenbergh M, Sinn P, Schem C, Hanusch C, Untch M, Loibl S. Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy. Lancet Oncol. 2018;19(1):40–50. https://doi.org/10.1016/S1470-2045(17)30904-X. (Epub 2017 Dec 7 PMID: 29233559).

Article  PubMed  Google Scholar 

Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)–a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81. https://doi.org/10.1016/j.jbi.2008.08.010. (PMID: 18929686; PMCID: PMC2700030).

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