Yoshio T, Okamoto H, Hirohata S, Minota S. IgG anti-NR2 glutamate receptor autoantibodies from patients with systemic lupus erythematosus activate endothelial cells. Arthritis Rheum. 2013;65(2):457–63.
Article CAS PubMed Google Scholar
Ballok DA, Millward JM, Sakic B. Neurodegeneration in autoimmune MRL-lpr mice as revealed by Fluoro Jade B staining. Brain Res. 2003;964(2):200–10.
Article CAS PubMed Google Scholar
Popescu A, Kao AH. Neuropsychiatric systemic lupus erythematosus. Curr Neuropharmacol. 2011;9(3):449–57.
Article CAS PubMed PubMed Central Google Scholar
Nishimura K, Harigai M, Omori M, Sato E, Hara M. Blood-brain barrier damage as a risk factor for corticosteroid-induced psychiatric disorders in systemic lupus erythematosus. Psychoneuroendocrinology. 2008;33(3):395–403.
Article CAS PubMed Google Scholar
Morales JY, Young-Stubbs CM, Shimoura CG, Kem WR, Uteshev VV, Mathis KW. Systemic administration of α7-nicotinic acetylcholine receptor ligands does not improve renal injury or behavior in mice with advanced systemic lupus erythematosus. Front Med. 2021;8:642960.
Zhai Q, Lai D, Cui P, Zhou R, Chen Q, Hou J, et al. Selective activation of basal forebrain cholinergic neurons attenuates polymicrobial sepsis-Induced inflammation via the cholinergic anti-inflammatory pathway. Crit Care Med. 2017;45(10):e1075–82.
Article CAS PubMed PubMed Central Google Scholar
Zaghloul N, Addorisio ME, Silverman HA, Patel HL, Valdés-Ferrer SI, Ayasolla KR, et al. Forebrain Cholinergic dysfunction and systemic and brain inflammation in murine Sepsis survivors. Front Immunol. 2017;8:1673.
Article PubMed PubMed Central Google Scholar
Nizri E, Irony-Tur-Sinai M, Lory O, Orr-Urtreger A, Lavi E, Brenner T. Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses. J Immunol. 2009;183(10):6681–8.
Article CAS PubMed Google Scholar
Goldstein RS, Bruchfeld A, Yang L, Qureshi AR, Gallowitsch-Puerta M, Patel NB, et al. Cholinergic anti-inflammatory pathway activity and high mobility group box-1 (HMGB1) serum levels in patients with rheumatoid arthritis. Mol Med 2007;13(3–4):210–5.
Article CAS PubMed PubMed Central Google Scholar
Pham GS, Shimoura CG, Chaudhari S, Kulp DV, Mathis KW. Chronic unilateral cervical vagotomy reduces renal inflammation, blood pressure, and renal injury in a mouse model of lupus. Am J Physiol Ren Physiol. 2020;319(2):F155–f61.
Mathis KW. An impaired neuroimmune pathway promotes the development of hypertension in systemic lupus erythematosus. Am J Physiol Regul Integr Comp Physiol. 2015;309(9):R1074–7.
Article CAS PubMed PubMed Central Google Scholar
Fairley AS, Mathis KW. Cholinergic agonists reduce blood pressure in a mouse model of systemic lupus erythematosus. Physiological Rep. 2017;5(7):e13213.
Huang F, Tang B, Jiang H. Optogenetic investigation of neuropsychiatric diseases. Int J Neurosci. 2013;123(1):7–16.
Karnopp TE, Chapacais GF, Freitas EC, Monticielo OA. Lupus animal models and neuropsychiatric implications. Clin Rheumatol. 2021;40(7):2535–45.
Yun Y, Wang X, Xu J, Jin C, Chen J, Wang X, et al. Pristane induced lupus mice as a model for neuropsychiatric lupus (NPSLE). Behav brain functions: BBF. 2023;19(1):3.
Article CAS PubMed PubMed Central Google Scholar
Luciano-Jaramillo J, Sandoval-García F, Vázquez-Del Mercado M, Gutiérrez-Mercado YK, Navarro-Hernández RE, Martínez-García EA, et al. Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice. PLoS ONE. 2019;14(9):e0217190.
Article CAS PubMed PubMed Central Google Scholar
Karnopp TE, Freitas EC, Rieger A, Chapacais GF, Monticielo OA. Higher IgG level correlated with vitamin D receptor in the hippocampus of a pristane-induced lupus model. Clin Rheumatol. 2022;41(6):1859–66.
Sato A, Sato Y, Uchida S. Activation of the intracerebral cholinergic nerve fibers originating in the basal forebrain increases regional cerebral blood flow in the rat’s cortex and hippocampus. Neurosci Lett. 2004;361(1–3):90–3.
Article CAS PubMed Google Scholar
Saeed RW, Varma S, Peng-Nemeroff T, Sherry B, Balakhaneh D, Huston J, et al. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med. 2005;201(7):1113–23.
Article CAS PubMed PubMed Central Google Scholar
LaLumiere RT. A new technique for controlling the brain: optogenetics and its potential for use in research and the clinic. Brain Stimul. 2011;4(1):1–6.
Krook-Magnuson E, Armstrong C, Bui A, Lew S, Oijala M, Soltesz I. In vivo evaluation of the dentate gate theory in epilepsy. J Physiol. 2015;593(10):2379–88.
Article CAS PubMed PubMed Central Google Scholar
Soper C, Wicker E, Kulick CV, N’Gouemo P, Forcelli PA. Optogenetic activation of superior colliculus neurons suppresses seizures originating in diverse brain networks. Neurobiol Dis. 2016;87:102–15.
Sohal VS, Zhang F, Yizhar O, Deisseroth K. Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature. 2009;459(7247):698–702.
Article CAS PubMed PubMed Central Google Scholar
Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 2013;493(7433):532–6.
Article CAS PubMed Google Scholar
Pavlov VA, Ochani M, Gallowitsch-Puerta M, Ochani K, Huston JM, Czura CJ, et al. Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia. Proc Natl Acad Sci USA. 2006;103(13):5219–23.
Article CAS PubMed PubMed Central Google Scholar
van Maanen MA, Lebre MC, van der Poll T, LaRosa GJ, Elbaum D, Vervoordeldonk MJ, et al. Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice. Arthritis Rheum. 2009;60(1):114–22.
van Maanen MA, Stoof SP, Larosa GJ, Vervoordeldonk MJ, Tak PP. Role of the cholinergic nervous system in rheumatoid arthritis: aggravation of arthritis in nicotinic acetylcholine receptor α7 subunit gene knockout mice. Ann Rheum Dis. 2010;69(9):1717–23.
Pham GS, Wang LA, Mathis KW. Pharmacological potentiation of the efferent vagus nerve attenuates blood pressure and renal injury in a murine model of systemic lupus erythematosus. Am J Physiol Regul Integr Comp Physiol. 2018;315(6):R1261–r71.
Article PubMed PubMed Central Google Scholar
Sato A, Sato Y, Uchida S. Regulation of cerebral cortical blood flow by the basal forebrain cholinergic fibers and aging. Auton neuroscience: basic Clin. 2002;96(1):13–9.
Abbruscato TJ, Lopez SP, Mark KS, Hawkins BT, Davis TP. Nicotine and cotinine modulate cerebral microvascular permeability and protein expression of ZO-1 through nicotinic acetylcholine receptors expressed on brain endothelial cells. J Pharm Sci. 2002;91(12):2525–38.
Article CAS PubMed Google Scholar
Hawkins BT, Egleton RD, Davis TP. Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors. Am J Physiol Heart Circ Physiol. 2005;289(1):H212–9.
Article CAS PubMed Google Scholar
Heeschen C, Weis M, Aicher A, Dimmeler S, Cooke JP. A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors. J Clin Investig. 2002;110(4):527–36.
Article CAS PubMed PubMed Central Google Scholar
Wang Y, Pereira EF, Maus AD, Ostlie NS, Navaneetham D, Lei S, et al. Human bronchial epithelial and endothelial cells express alpha7 nicotinic acetylcholine receptors. Mol Pharmacol. 2001;60(6):1201–9.
Article CAS PubMed Google Scholar
Li YZ, Liu XH, Rong F, Hu S, Sheng ZY. Carbachol inhibits TNF-α-induced endothelial barrier dysfunction through alpha 7 nicotinic receptors. Acta Pharmacol Sin. 2010;31(10):1389–94.
Article CAS PubMed PubMed Central Google Scholar
Huang H, Lavoie-Lamoureux A, Lavoie JP. Cholinergic stimulation attenuates the IL-4 induced expression of E-selectin and vascular endothelial growth factor by equine pulmonary artery endothelial cells. Vet Immunol Immunopathol. 2009;132(2–4):116–21.
Comments (0)