aAcademic Department of Gastroenterology & Liver Unit, Royal Hallamshire Hospital

bDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK

Correspondence to Professor Reena Sidhu, Consultant Gastroenterologist & Hon Professor, Room P12, P Floor, Department of Gastroenterology, Royal Hallamshire Hospital, Glossop Road, Room P11 Sheffield S10 2JF, United Kingdom. Tel: +44 114 2261180; e-mail: [email protected]