Parkinson Disease Dementia Management: an Update of Current Evidence and Future Directions

Braak H, Ghebremedhin E, Rüb U, Bratzke H, Del Tredici K. Stages in the development of Parkinson’s disease-related pathology. Cell Tissue Res. 2004;318(1):121–34. https://doi.org/10.1007/s00441-004-0956-9.

Article  PubMed  Google Scholar 

Pringsheim T, Jette N, Frolkis A, Steeves TD. The prevalence of Parkinson’s disease: a systematic review and meta-analysis. Mov Disord. 2014;29(13):1583–90. https://doi.org/10.1002/mds.25945.

Article  PubMed  Google Scholar 

Bohnen NI, Kaufer DI, Hendrickson R, Ivanco LS, Lopresti BJ, Constantine GM, et al. Cognitive correlates of cortical cholinergic denervation in Parkinson’s disease and parkinsonian dementia. J Neurol. 2006;253(2):242–7. https://doi.org/10.1007/s00415-005-0971-0.

Article  CAS  PubMed  Google Scholar 

Braak H, Rüb U, Jansen Steur EN, Del Tredici K, de Vos RA. Cognitive status correlates with neuropathologic stage in Parkinson disease. Neurology. 2005;64(8):1404–10. https://doi.org/10.1212/01.Wnl.0000158422.41380.82.

Article  CAS  PubMed  Google Scholar 

Irwin DJ, White MT, Toledo JB, Xie SX, Robinson JL, Van Deerlin V, et al. Neuropathologic substrates of Parkinson disease dementia. Ann Neurol. 2012;72(4):587–98. https://doi.org/10.1002/ana.23659.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Siderowf A, Xie SX, Hurtig H, Weintraub D, Duda J, Chen-Plotkin A, et al. CSF amyloid beta 1–42 predicts cognitive decline in Parkinson disease. Neurology. 2010;75(12):1055–61. https://doi.org/10.1212/WNL.0b013e3181f39a78.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alves G, Lange J, Blennow K, Zetterberg H, Andreasson U, Førland MG, et al. CSF Aβ42 predicts early-onset dementia in Parkinson disease. Neurology. 2014;82(20):1784–90. https://doi.org/10.1212/wnl.0000000000000425.

Article  CAS  PubMed  Google Scholar 

Leroi I, McDonald K, Pantula H, Harbishettar V. Cognitive impairment in Parkinson disease: impact on quality of life, disability, and caregiver burden. J Geriatr Psychiatry Neurol. 2012;25(4):208–14. https://doi.org/10.1177/0891988712464823.

Article  PubMed  Google Scholar 

Irwin DJ, Grossman M, Weintraub D, Hurtig HI, Duda JE, Xie SX, et al. Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis. Lancet Neurol. 2017;16(1):55–65. https://doi.org/10.1016/s1474-4422(16)30291-5.

Article  PubMed  PubMed Central  Google Scholar 

Jellinger KA. Are there morphological differences between Parkinson’s disease-dementia and dementia with Lewy bodies? Parkinsonism Relat Disord. 2022;100:24–32. https://doi.org/10.1016/j.parkreldis.2022.05.024.

Article  CAS  PubMed  Google Scholar 

Friedman JH. Dementia with Lewy bodies and Parkinson disease dementia: it is the same disease! Parkinsonism Relat Disord. 2018;46(Suppl 1):S6–9. https://doi.org/10.1016/j.parkreldis.2017.07.013.

Article  PubMed  Google Scholar 

Jellinger KA. Dementia with Lewy bodies and Parkinson’s disease-dementia: current concepts and controversies. J Neural Transm (Vienna). 2018;125(4):615–50. https://doi.org/10.1007/s00702-017-1821-9.

Article  CAS  PubMed  Google Scholar 

McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, et al. Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the DLB Consortium. Neurology. 2017;89(1):88–100. https://doi.org/10.1212/wnl.0000000000004058.

Article  PubMed  PubMed Central  Google Scholar 

Aarsland D, Zaccai J, Brayne C. A systematic review of prevalence studies of dementia in Parkinson’s disease. Mov Disord. 2005;20(10):1255–63. https://doi.org/10.1002/mds.20527.

Article  PubMed  Google Scholar 

Muslimovic D, Post B, Speelman JD, Schmand B. Cognitive profile of patients with newly diagnosed Parkinson disease. Neurology. 2005;65(8):1239–45. https://doi.org/10.1212/01.wnl.0000180516.69442.95.

Article  PubMed  Google Scholar 

Aarsland D, Kurz MW. The epidemiology of dementia associated with Parkinson disease. J Neurol Sci. 2010;289(1–2):18–22. https://doi.org/10.1016/j.jns.2009.08.034.

Article  PubMed  Google Scholar 

Emre M, Aarsland D, Brown R, Burn DJ, Duyckaerts C, Mizuno Y, et al. Clinical diagnostic criteria for dementia associated with Parkinson’s disease. Mov Disord. 2007;22(12):1689–707. https://doi.org/10.1002/mds.21507.

Guo Y, Liu FT, Hou XH, Li JQ, Cao XP, Tan L, et al. Predictors of cognitive impairment in Parkinson’s disease: a systematic review and meta-analysis of prospective cohort studies. J Neurol. 2021;268(8):2713–22. https://doi.org/10.1007/s00415-020-09757-9.

Article  CAS  PubMed  Google Scholar 

Guo Y, Xu W, Liu FT, Li JQ, Cao XP, Tan L, et al. Modifiable risk factors for cognitive impairment in Parkinson’s disease: a systematic review and meta-analysis of prospective cohort studies. Mov Disord. 2019;34(6):876–83. https://doi.org/10.1002/mds.27665.

Article  PubMed  Google Scholar 

Pigott K, Rick J, Xie SX, Hurtig H, Chen-Plotkin A, Duda JE, et al. Longitudinal study of normal cognition in Parkinson disease. Neurology. 2015;85(15):1276–82. https://doi.org/10.1212/wnl.0000000000002001.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Phongpreecha T, Cholerton B, Mata IF, Zabetian CP, Poston KL, Aghaeepour N, et al. Multivariate prediction of dementia in Parkinson’s disease. NPJ Parkinsons Dis. 2020;6:20. https://doi.org/10.1038/s41531-020-00121-2.

Article  PubMed  PubMed Central  Google Scholar 

Parsons TD, Rogers SA, Braaten AJ, Woods SP, Tröster AI. Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson’s disease: a meta-analysis. Lancet Neurol. 2006;5(7):578–88. https://doi.org/10.1016/s1474-4422(06)70475-6.

Article  PubMed  Google Scholar 

Wyman-Chick KA. Verbal Fluency in Parkinson’s patients with and without bilateral deep brain stimulation of the subthalamic nucleus: a meta-analysis. J Int Neuropsychol Soc. 2016;22(4):478–85. https://doi.org/10.1017/s1355617716000035.

Article  PubMed  Google Scholar 

Follett KA, Weaver FM, Stern M, Hur K, Harris CL, Luo P, et al. Pallidal versus subthalamic deep-brain stimulation for Parkinson’s disease. N Engl J Med. 2010;362(22):2077–91. https://doi.org/10.1056/NEJMoa0907083.

Article  CAS  PubMed  Google Scholar 

Weaver FM, Follett KA, Stern M, Luo P, Harris CL, Hur K, et al. Randomized trial of deep brain stimulation for Parkinson disease: thirty-six-month outcomes. Neurology. 2012;79(1):55–65. https://doi.org/10.1212/WNL.0b013e31825dcdc1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Massano J, Garrett C. Deep brain stimulation and cognitive decline in Parkinson’s disease: a clinical review. Front Neurol. 2012;3:66. https://doi.org/10.3389/fneur.2012.00066.

Article  PubMed  PubMed Central  Google Scholar 

• Bove F, Fraix V, Cavallieri F, Schmitt E, Lhommée E, Bichon A, et al. Dementia and subthalamic deep brain stimulation in Parkinson disease: a long-term overview. Neurology. 2020;95(4):e384–92. https://doi.org/10.1212/wnl.0000000000009822. An important analysis of a large cohort of subthalamic nucleus DBS PD patients indicating that dementia is not more common in this population than in general PD population.

Aybek S, Gronchi-Perrin A, Berney A, Chiuvé SC, Villemure JG, Burkhard PR, et al. Long-term cognitive profile and incidence of dementia after STN-DBS in Parkinson’s disease. Mov Disord. 2007;22(7):974–81. https://doi.org/10.1002/mds.21478.

Article  PubMed  Google Scholar 

Odekerken VJ, Boel JA, Geurtsen GJ, Schmand BA, Dekker IP, de Haan RJ, et al. Neuropsychological outcome after deep brain stimulation for Parkinson disease. Neurology. 2015;84(13):1355–61. https://doi.org/10.1212/wnl.0000000000001419.

Article  CAS  PubMed  Google Scholar 

Boel JA, Odekerken VJ, Schmand BA, Geurtsen GJ, Cath DC, Figee M, et al. Cognitive and psychiatric outcome 3 years after globus pallidus pars interna or subthalamic nucleus deep brain stimulation for Parkinson’s disease. Parkinsonism Relat Disord. 2016;33:90–5. https://doi.org/10.1016/j.parkreldis.2016.09.018.

Article  PubMed  Google Scholar 

Combs HL, Folley BS, Berry DT, Segerstrom SC, Han DY, Anderson-Mooney AJ, et al. Cognition and depression following deep brain stimulation of the subthalamic nucleus and globus pallidus pars internus in Parkinson’s disease: a meta-analysis. Neuropsychol Rev. 2015;25(4):439–54. https://doi.org/10.1007/s11065-015-9302-0.

Article  PubMed  Google Scholar 

Hoops S, Nazem S, Siderowf AD, Duda JE, Xie SX, Stern MB, et al. Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease. Neurology. 2009;73(21):1738–45. https://doi.org/10.1212/WNL.0b013e3181c34b47.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dalrymple-Alford JC, MacAskill MR, Nakas CT, Livingston L, Graham C, Crucian GP, et al. The MoCA: well-suited screen for cognitive impairment in Parkinson disease. Neurology. 2010;75(19):1717–25. https://doi.org/10.1212/WNL.0b013e3181fc29c9.

Article  CAS  PubMed  Google Scholar 

Snyder A, Gruber-Baldini AL, Rainer von Coelln F, Savitt JM, Reich SG, Armstrong MJ, et al. Comparison of Mini-Mental State Examination and Montreal Cognitive Assessment ratings across levels of Parkinson’s disease severity. J Parkinsons Dis. 2021;11(4):1995–2003. https://doi.org/10.3233/jpd-212705.

Goldman JG, Holden S, Ouyang B, Bernard B, Goetz CG, Stebbins GT. Diagnosing PD-MCI by MDS Task Force criteria: how many and which neuropsychological tests? Mov Disord. 2015;30(3):402–6. https://doi.org/10.1002/mds.26084.

Article  PubMed  Google Scholar 

Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, et al. Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001;56(9):1143–53. https://doi.org/10.1212/wnl.56.9.1143.

Galvin JE, Pollack J, Morris JC. Clinical phenotype of Parkinson disease dementia. Neurology. 2006;67(9):1605–11. https://doi.org/10.1212/01.wnl.0000242630.52203.8f.

Article  PubMed  Google Scholar 

Reijnders JS, Ehrt U, Weber WE, Aarsland D, Leentjens AF. A systematic review of prevalence studies of depression in Parkinson’s disease. Mov Disord. 2008;23(2):183–9; quiz 313. https://doi.org/10.1002/mds.21803.

Torbey E, Pachana NA, Dissanayaka NN. Depression rating scales in Parkinson’s disease: a critical review updating recent literature. J Affect Disord. 2015;184:216–24. https://doi.org/10.1016/j.jad.2015.05.059.

Article 

留言 (0)

沒有登入
gif